Muse’s AI Platform Delivers Clinical-Grade Sleep and Brain Health Intelligence

June 03, 2025 at 07:00 AM EDT

With a foundation brain model trained on the world’s largest EEG dataset, Muse enables remote clinical-grade sleep intelligence and adaptive brain health monitoring.

Muse has reached a major milestone with the recent launch of Muse S Athena, the first wearable to integrate clinical-grade EEG, fNIRS, and SpO₂ in a lightweight, consumer-friendly form. This breakthrough marks a pivotal step toward Muse’s broader vision: transforming a wearable into a scalable, AI-powered platform for brain-based diagnostics.

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Muse S Athena Headband

By combining real-time biosignal data with foundation models inspired by the architecture behind GPTs, Athena delivers expert-level sleep staging and insights from home. This enables researchers, clinicians, and consumers to access precise, contextual, and longitudinal insights that were previously only available in a lab.

“We’re seeing powerful evidence that foundation models can transform how we interpret brain data,” said Chris Aimone, Muse co-founder and Chief Innovation Officer. “What GPTs did for language, this architecture is beginning to do for neural signals—revealing patterns that are both highly individualized and deeply generalizable.”

Muse Trains AI to Understand the Language of the Brain

Muse has built the world’s largest longitudinal EEG dataset—over 1 billion minutes of brain activity from more than 16 million sessions—spanning meditation, sleep, and cognitive use cases. This data underpins the Muse Foundational Brain Model (FBM): a deep-learning architecture akin to a large language model, but trained to decode the brain.

The FBM–a transformer-based neural network model like those that underlie Large Language models like ChatGPT–is trained on vast, contextual, multimodal datasets. Translation layers allow the FBM to interface with the latest generative AI intelligences to augment their capabilities with neural insights. This integrated AI stack enables:

Clustering individuals based on neural patterns that may reflect cognitive resilience or early decline
Detection of subtle anomalies in recovery that may indicate emerging neurological issues
Interpreting real-time brain states using multimodal data streams including EEG, SpO₂, and fNIRS

Because the FBM has been trained on such a wide variety of real-world brain sessions, the FBM can be fine-tuned for new applications—accelerating development in areas like cognitive decline, mental health, and digital therapeutics without costly new datasets.

“We’re no longer looking at EEG as static metrics,” said Nadia Kumentas, Muse’s Chief Marketing Officer.“To us, brain activity is a living, contextual language—one that foundation models can learn, interpret, and translate into actionable insight.”

Expert-Level Sleep Staging, Now On Your Nightstand

In a major clinical milestone, Muse has demonstrated sleep staging accuracy on par with expert sleep scorers using PSG-labeled datasets, validated across both retrospective and real-time testing. Going beyond human capabilities, Muse’s proprietary mEEG signal and Foundational Brain Model now deliver not only lab-grade scoring precision in a fully wearable form factor, but also deeper insights—such as staging macro and microarchitecture of sleep even in the presence of environmental noise.

“What we’ve achieved with Athena confirms that Muse is more than a consumer device—it’s a clinical-grade platform ready to support real-world research, decentralized trials, and the future of at-home diagnostics,” said Jean-Michel Fournier, Chief Executive Officer of Muse.

This level of accuracy enables frictionless, longitudinal sleep scoring in home environments—reducing cost and complexity in clinical trials while providing reliable, precision insights to end-users.

Smarter Sleep Apnea Research Starts at the Forehead

Muse now makes it possible to measure blood oxygen levels (SpO₂) from the forehead—bringing a critical tool for sleep apnea and respiratory research out of the lab and into the home.

Through its latest device, Muse S Athena, high-performance SpO₂ monitoring adds a vital respiratory layer to Muse’s neurotechnology platform. Unlike traditional fingertip sensors, the forehead placement enables faster response times and more stable readings throughout the night—especially important for detecting rapid changes in oxygen linked to sleep-disordered breathing.

This feature is now rolling out for research partners and, when paired with EEG and fNIRS, gives researchers unprecedented visibility into the brain, circulatory, and respiratory systems—all captured in real time, from a single wearable, at scale.

Already in use across studies in cognitive decline, long COVID, stroke recovery, and digital therapeutics, Muse’s infrastructure supports rapid experimentation, population-level insights, and plug-in potential for pharma, research, and health tech.

Muse is fast becoming the platform layer between biosignal-rich data and intelligent diagnostics—delivering real-time neuroscience at the edge of the home, the clinic, and the future of personalized medicine.

About Muse

Muse is pioneering brain health through its industry-leading mEEG platform, built on advanced AI algorithms. Muse spearheads decentralized research initiatives focused on enhancing mental health, optimizing sleep, and advancing cognitive performance through innovative neurotechnology. Muse’s AI-driven neurotech tools empower researchers, developers, and consumers worldwide, and are underpinned by over 200 third-party-led research studies from renowned institutions including the Mayo Clinic, MIT, and Harvard. Muse has collected and decoded over 1 billion minutes of brain data to date, comprising one of the largest EEG collections in the world. Muse is headquartered in Toronto, Canada.

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