Ardea
Biosciences, Inc.
|
||
(Name
of Issuer)
|
||
Common
Shares, no par value
|
||
(Title
of Class of Securities)
|
||
03969P107
|
||
(CUSIP
Number)
|
||
December
31, 2009
|
||
(Date
of Event Which Requires Filing of this Statement)
|
o |
Rule 13d-1(b)
|
|
x |
Rule 13d-1(c)
|
|
o |
Rule 13d-1(d)
|
|
CUSIP
No. 03969P107
|
13G/A
|
Page
2 of 13 Pages
|
1
|
NAME
OF REPORTING PERSON:
Andreeff
Equity Advisors, L.L.C.
|
||||||||||
2
|
CHECK
THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
|
||||||||||
3
|
SEC
USE ONLY
|
||||||||||
4
|
CITIZENSHIP
OR PLACE OF ORGANIZATION
|
||||||||||
Delaware
|
|||||||||||
5
|
SOLE
VOTING POWER
|
||||||||||
NUMBER
OF
|
0
|
||||||||||
SHARES
|
|||||||||||
BENEFICIALLY
|
6
|
SHARED
VOTING POWER
|
|||||||||
OWNED
|
575,636
|
||||||||||
BY
|
|||||||||||
EACH
|
7
|
SOLE
DISPOSITIVE POWER
|
|||||||||
REPORTING
|
0
|
||||||||||
PERSON
|
|||||||||||
WITH:
|
8
|
SHARED
DISPOSITIVE POWER
|
|||||||||
575,636
|
|||||||||||
9
|
AGGREGATE
AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
|
||||||||||
575,636
|
|||||||||||
10
|
CHECK
IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
SHARES*
|
o
|
|||||||||
11
|
PERCENT
OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
|
||||||||||
3.1%
|
|||||||||||
12
|
TYPE
OF REPORTING PERSON*
|
||||||||||
IA,
OO
|
CUSIP
No. 03969P107
|
13G/A
|
Page 3
of 13 Pages
|
1
|
NAME
OF REPORTING PERSON:
Dane
Andreeff
|
||||||||||
2
|
CHECK
THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
|
||||||||||
3
|
SEC
USE ONLY
|
||||||||||
4
|
CITIZENSHIP
OR PLACE OF ORGANIZATION
|
||||||||||
Canada
|
|||||||||||
5
|
SOLE
VOTING POWER
|
||||||||||
NUMBER
OF
|
583,205
|
||||||||||
SHARES
|
|||||||||||
BENEFICIALLY
|
6
|
SHARED
VOTING POWER
|
|||||||||
OWNED
|
575,636
|
||||||||||
BY
|
|||||||||||
EACH
|
7
|
SOLE
DISPOSITIVE POWER
|
|||||||||
REPORTING
|
583,205
|
||||||||||
PERSON
|
|||||||||||
WITH:
|
8
|
SHARED
DISPOSITIVE POWER
|
|||||||||
575,636
|
|||||||||||
9
|
AGGREGATE
AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
|
||||||||||
1,158,841
|
|||||||||||
10
|
CHECK
IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
SHARES*
|
o
|
|||||||||
11
|
PERCENT
OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
|
||||||||||
6.3%
|
|||||||||||
12
|
TYPE
OF REPORTING PERSON*
|
||||||||||
IN,
HC
|
CUSIP
No. 03969P107
|
13G/A
|
Page 4
of 13 Pages
|
1
|
NAME
OF REPORTING PERSON:
Maple
Leaf Capital I, L.L.C.
|
||||||||||
2
|
CHECK
THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
|
||||||||||
3
|
SEC
USE ONLY
|
||||||||||
4
|
CITIZENSHIP
OR PLACE OF ORGANIZATION
|
||||||||||
Delaware
|
|||||||||||
5
|
SOLE
VOTING POWER
|
||||||||||
NUMBER
OF
|
0
|
||||||||||
SHARES
|
|||||||||||
BENEFICIALLY
|
6
|
SHARED
VOTING POWER
|
|||||||||
OWNED
|
145,534
|
||||||||||
BY
|
|||||||||||
EACH
|
7
|
SOLE
DISPOSITIVE POWER
|
|||||||||
REPORTING
|
0
|
||||||||||
PERSON
|
|||||||||||
WITH:
|
8
|
SHARED
DISPOSITIVE POWER
|
|||||||||
145,534
|
|||||||||||
9
|
AGGREGATE
AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
|
||||||||||
145,534
|
|||||||||||
10
|
CHECK
IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
SHARES*
|
o
|
|||||||||
11
|
PERCENT
OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
|
||||||||||
0.8%
|
|||||||||||
12
|
TYPE
OF REPORTING PERSON*
|
||||||||||
CO,
HC
|
CUSIP
No. 03969P107
|
13G/A
|
Page 5
of 13 Pages
|
1
|
NAME
OF REPORTING PERSON:
Maple
Leaf Partners, L.P.
|
||||||||||
2
|
CHECK
THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
|
||||||||||
3
|
SEC
USE ONLY
|
||||||||||
4
|
CITIZENSHIP
OR PLACE OF ORGANIZATION
|
||||||||||
Delaware
|
|||||||||||
5
|
SOLE
VOTING POWER
|
||||||||||
NUMBER
OF
|
0
|
||||||||||
SHARES
|
|||||||||||
BENEFICIALLY
|
6
|
SHARED
VOTING POWER
|
|||||||||
OWNED
|
43,326
|
||||||||||
BY
|
|||||||||||
EACH
|
7
|
SOLE
DISPOSITIVE POWER
|
|||||||||
REPORTING
|
0
|
||||||||||
PERSON
|
|||||||||||
WITH:
|
8
|
SHARED
DISPOSITIVE POWER
|
|||||||||
43,326
|
|||||||||||
9
|
AGGREGATE
AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
|
||||||||||
43,326
|
|||||||||||
10
|
CHECK
IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
SHARES*
|
o
|
|||||||||
11
|
PERCENT
OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
|
||||||||||
0.2%
|
|||||||||||
12
|
TYPE
OF REPORTING PERSON*
|
||||||||||
PN
|
CUSIP
No. 03969P107
|
13G/A
|
Page 6
of 13 Pages
|
1
|
NAME
OF REPORTING PERSON:
Maple
Leaf Partners I, L.P.
|
||||||||||
2
|
CHECK
THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
|
||||||||||
3
|
SEC
USE ONLY
|
||||||||||
4
|
CITIZENSHIP
OR PLACE OF ORGANIZATION
|
||||||||||
Delaware
|
|||||||||||
5
|
SOLE
VOTING POWER
|
||||||||||
NUMBER
OF
|
0
|
||||||||||
SHARES
|
|||||||||||
BENEFICIALLY
|
6
|
SHARED
VOTING POWER
|
|||||||||
OWNED
|
52,508
|
||||||||||
BY
|
|||||||||||
EACH
|
7
|
SOLE
DISPOSITIVE POWER
|
|||||||||
REPORTING
|
0
|
||||||||||
PERSON
|
|||||||||||
WITH:
|
8
|
SHARED
DISPOSITIVE POWER
|
|||||||||
52,508
|
|||||||||||
9
|
AGGREGATE
AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
|
||||||||||
52,508
|
|||||||||||
10
|
CHECK
IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
SHARES*
|
o
|
|||||||||
11
|
PERCENT
OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
|
||||||||||
0.3%
|
|||||||||||
12
|
TYPE
OF REPORTING PERSON*
|
||||||||||
PN
|
CUSIP
No. 03969P107
|
13G/A
|
Page 7
of 13 Pages
|
1
|
NAME
OF REPORTING PERSON:
Maple
Leaf Discovery, L.P.
|
||||||||||
2
|
CHECK
THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
|
||||||||||
3
|
SEC
USE ONLY
|
||||||||||
4
|
CITIZENSHIP
OR PLACE OF ORGANIZATION
|
||||||||||
Delaware
|
|||||||||||
5
|
SOLE
VOTING POWER
|
||||||||||
NUMBER
OF
|
0
|
||||||||||
SHARES
|
|||||||||||
BENEFICIALLY
|
6
|
SHARED
VOTING POWER
|
|||||||||
OWNED
|
7,275
|
||||||||||
BY
|
|||||||||||
EACH
|
7
|
SOLE
DISPOSITIVE POWER
|
|||||||||
REPORTING
|
0
|
||||||||||
PERSON
|
|||||||||||
WITH:
|
8
|
SHARED
DISPOSITIVE POWER
|
|||||||||
7,275
|
|||||||||||
9
|
AGGREGATE
AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
|
||||||||||
7,275
|
|||||||||||
10
|
CHECK
IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
SHARES*
|
o
|
|||||||||
11
|
PERCENT
OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
|
||||||||||
0.04%
|
|||||||||||
12
|
TYPE
OF REPORTING PERSON*
|
||||||||||
PN
|
CUSIP
No. 03969P107
|
13G/A
|
Page 8
of 13 Pages
|
1
|
NAME
OF REPORTING PERSON:
Maple
Leaf Discovery I, L.P.
|
||||||||||
2
|
CHECK
THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
|
||||||||||
3
|
SEC
USE ONLY
|
||||||||||
4
|
CITIZENSHIP
OR PLACE OF ORGANIZATION
|
||||||||||
Delaware
|
|||||||||||
5
|
SOLE
VOTING POWER
|
||||||||||
NUMBER
OF
|
0
|
||||||||||
SHARES
|
|||||||||||
BENEFICIALLY
|
6
|
SHARED
VOTING POWER
|
|||||||||
OWNED
|
42,425
|
||||||||||
BY
|
|||||||||||
EACH
|
7
|
SOLE
DISPOSITIVE POWER
|
|||||||||
REPORTING
|
0
|
||||||||||
PERSON
|
|||||||||||
WITH:
|
8
|
SHARED
DISPOSITIVE POWER
|
|||||||||
42,425
|
|||||||||||
9
|
AGGREGATE
AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
|
||||||||||
42,425
|
|||||||||||
10
|
CHECK
IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
SHARES*
|
o
|
|||||||||
11
|
PERCENT
OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
|
||||||||||
0.2%
|
|||||||||||
12
|
TYPE
OF REPORTING PERSON*
|
||||||||||
PN
|
CUSIP
No. 03969P107
|
13G/A
|
Page 9
of 13 Pages
|
1
|
NAME
OF REPORTING PERSON:
Maple
Leaf Offshore, Ltd.
|
||||||||||
2
|
CHECK
THE APPROPRIATE BOX IF A MEMBER OF A GROUP*
|
||||||||||
3
|
SEC
USE ONLY
|
||||||||||
4
|
CITIZENSHIP
OR PLACE OF ORGANIZATION
|
||||||||||
Cayman
Islands
|
|||||||||||
5
|
SOLE
VOTING POWER
|
||||||||||
NUMBER
OF
|
0
|
||||||||||
SHARES
|
|||||||||||
BENEFICIALLY
|
6
|
SHARED
VOTING POWER
|
|||||||||
OWNED
|
430,102
|
||||||||||
BY
|
|||||||||||
EACH
|
7
|
SOLE
DISPOSITIVE POWER
|
|||||||||
REPORTING
|
0
|
||||||||||
PERSON
|
|||||||||||
WITH:
|
8
|
SHARED
DISPOSITIVE POWER
|
|||||||||
430,102
|
|||||||||||
9
|
AGGREGATE
AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
|
||||||||||
430,102
|
|||||||||||
10
|
CHECK
IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN
SHARES*
|
o
|
|||||||||
11
|
PERCENT
OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
|
||||||||||
2.3%
|
|||||||||||
12
|
TYPE
OF REPORTING PERSON*
|
||||||||||
CO
|
CUSIP
No. 03969P107
|
13G/A
|
Page 10
of 13 Pages
|
ITEM
1(a).
|
NAME
OF ISSUER:
|
Ardea
Biosciences, Inc.
|
ITEM
1(b).
|
ADDRESS
OF ISSUER'S PRINCIPAL EXECUTIVE OFFICES:
|
4939
Directors Place
|
|
San
Diego, CA 92121
|
|
ITEM
2(a).
|
NAME
OF PERSON FILING:
|
This
Schedule 13G/A is being filed on behalf of the following persons (the
“Reporting Persons”):
|
(i)
|
Andreeff
Equity Advisors, L.L.C. (“AEA”)
|
||
(ii)
|
Dane
Andreeff
|
||
(iii)
|
Maple
Leaf Capital I, L.L.C. (“Capital”)
|
||
(iv)
|
Maple
Leaf Partners, L.P. (“MLP”)
|
||
(v)
|
Maple
Leaf Partners I, L.P. (“MLPI”)
|
||
(vi)
|
Maple
Leaf Discovery, L.P. (“MLD”)
|
||
(vii)
|
Maple
Leaf Discovery I, L.P. (“MLDI”)
|
||
(viii)
|
Maple
Leaf Offshore, Ltd. (“MLO”)
|
ITEM
2(b).
|
ADDRESS
OF PRINCIPAL BUSINESS OFFICE:
|
The principal business
office of each of the Reporting Persons filing this Schedule 13G/A is
located at 140 East St. Lucia Lane, Santa Rosa Beach, FL
32459.
|
ITEM
2(c).
|
CITIZENSHIP:
|
(i)
|
AEA
|
Delaware
limited liability company
|
|
(ii)
|
Dane
Andreeff
|
Canada
|
|
(iii)
|
Capital
|
Delaware
limited liability company
|
|
(iv)
|
MLP
|
Delaware
limited partnership
|
|
(v)
|
MLPI
|
Delaware
limited partnership
|
|
(vi)
|
MLD
|
Delaware
limited partnership
|
|
(vii)
|
MLDI
|
Delaware
limited partnership
|
|
(viii)
|
MLO
|
Cayman
Islands company
|
ITEM
2(d).
|
TITLE
OF CLASS OF SECURITIES:
|
Common
Shares, no par value
|
ITEM
2(e).
|
CUSIP
Number:
|
03969P107
|
CUSIP
No. 03969P107
|
13G/A
|
Page 11
of 13 Pages
|
ITEM
3. IF
THIS STATEMENT IS FILED PURSUANT TO RULE 13d-1(b), or 13d-2(b) or
(c) CHECK WHETHER THE PERSON FILING IS A:
|
|
Not
applicable.
|
ITEM
4.
|
OWNERSHIP:
|
Provide
the following information regarding the aggregate number and percentage of
the class of securities of the issuer identified in Item
1.
|
(a)
|
Amount
beneficially owned:
|
||
See
the responses to Item 9 on the attached cover pages.
|
|||
(b)
|
Percent
of class:
|
||
See
the responses to Item 11 on the attached cover pages.
|
|||
(c)
|
Number
of shares as to which the person has:
|
||
(i)
|
Sole
power to vote or to direct the vote
|
||
See
the responses to Item 5 on the attached cover pages.
|
|||
(ii)
|
Shared
power to vote or to direct the vote
|
||
See
the responses to Item 6 on the attached cover pages.
|
|||
(iii)
|
Sole
power to dispose or to direct the disposition of
|
||
See
the responses to Item 7 on the attached cover pages.
|
|||
(iv)
|
Shared
power to dispose or to direct the disposition
of
|
||
See
the responses to Item 8 on the attached cover
pages.
|
ITEM
5.
|
OWNERSHIP
OF FIVE PERCENT OR LESS OF A CLASS:
|
If this
statement is being filed to report the fact that as of the date hereof the
Reporting Persons have ceased to be the beneficial owner of more than five
percent of the class of securities check the following.o
|
ITEM
6.
|
OWNERSHIP
OF MORE THAN FIVE PERCENT ON BEHALF OF ANOTHER PERSON:
|
Not
applicable.
|
CUSIP
No. 03969P107
|
13G/A
|
Page 12
of 13 Pages
|
ITEM
7. IDENTIFICATION
AND CLASSIFICATION OF THE SUBSIDIARY WHICH ACQUIRED THE SECURITY BEING
REPORTED ON BY THE PARENT HOLDING COMPANY:
|
|
Mr. Andreeff is
the Managing Member of Andreeff Equity Advisors, L.L.C. (“AEA”) and Maple
Leaf Capital I, L.L.C. (“Capital”). AEA is the Investment Adviser
and Capital is the General Partner of the following limited partnerships,
which now own, in the aggregate, less than 5% of the issuer’s
securities:
|
(i)
|
Maple
Leaf Partners, L.P.
|
|
(ii)
|
Maple
Leaf Partners I, L.P.
|
|
(iii)
|
Maple
Leaf Discovery, L.P.
|
|
(iv)
|
Maple
Leaf Discovery I, L.P.
|
ITEM
8.
|
IDENTIFICATION
AND CLASSIFICATION OF MEMBERS OF A GROUP:
|
Not
applicable.
|
ITEM
9.
|
NOTICE
OF DISSOLUTION OF GROUP:
|
Not
applicable.
|
CUSIP
No. 03969P107
|
13G/A
|
Page 13
of 13 Pages
|
ITEM
10.
|
CERTIFICATION
|
Dated:
|
February
9, 2010
|
MAPLE
LEAF PARTNERS I, L.P.*
By: Dane
Andreeff
|
|||
/s/
Dane Andreeff
|
/s/
Dane Andreeff
|
||
Name: Dane
Andreeff *
|
Name:
Dane Andreeff
|
||
Title: Director
|
Title: Director
|
||
ANDREEFF
EQUITY ADVISORS, L.L.C.*
By: Dane
Andreeff
|
MAPLE
LEAF DISCOVERY, L.P.*
By: Dane
Andreeff
|
||
/s/
Dane Andreeff
|
/s/
Dane Andreeff
|
||
Name: Dane
Andreeff *
|
Name:
Dane Andreeff
|
||
Title: Managing
Member
|
Title: Director
|
||
MAPLE
LEAF CAPITAL I, L.L.C.*
|
MAPLE
LEAF DISCOVERY I, L.P.*
|
||
By: Dane
Andreeff
|
By: Dane
Andreeff
|
||
/s/
Dane Andreeff
|
/s/
Dane Andreeff
|
||
Name: Dane
Andreeff *
|
Name:
Dane Andreeff
|
||
Title: Managing
Member
|
Title: Director
|
||
MAPLE
LEAF PARTNERS, L.P.*
By: Dane
Andreeff
|
MAPLE
LEAF OFFSHORE, LTD.*
By: Dane
Andreeff
|
||
/s/
Dane Andreeff
|
/s/
Dane Andreeff
|
||
Name: Dane
Andreeff *
|
Name:
Dane Andreeff
|
||
Title: Director
|
Title: Director
|
MAPLE
LEAF PARTNERS I, L.P.*
By: Dane
Andreeff
|
|||
/s/
Dane Andreeff
|
/s/
Dane Andreeff
|
||
Name: Dane
Andreeff *
|
Name:
Dane Andreeff
|
||
Title: Director
|
Title: Director
|
||
ANDREEFF
EQUITY ADVISORS, L.L.C.*
By: Dane
Andreeff
|
MAPLE
LEAF DISCOVERY, L.P.*
By: Dane
Andreeff
|
||
/s/
Dane Andreeff
|
/s/
Dane Andreeff
|
||
Name: Dane
Andreeff *
|
Name:
Dane Andreeff
|
||
Title: Managing
Member
|
Title: Director
|
||
MAPLE
LEAF CAPITAL I, L.L.C.*
|
MAPLE
LEAF DISCOVERY I, L.P.*
|
||
By: Dane
Andreeff
|
By: Dane
Andreeff
|
||
/s/
Dane Andreeff
|
/s/
Dane Andreeff
|
||
Name: Dane
Andreeff *
|
Name:
Dane Andreeff
|
||
Title: Managing
Member
|
Title: Director
|
||
MAPLE
LEAF PARTNERS, L.P.*
By: Dane
Andreeff
|
MAPLE
LEAF OFFSHORE, LTD.*
By: Dane
Andreeff
|
||
/s/
Dane Andreeff
|
/s/
Dane Andreeff
|
||
Name: Dane
Andreeff *
|
Name:
Dane Andreeff
|
||
Title: Director
|
Title: Director
|
||