Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Expires: January 31, 2005
Estimated average burden hours per response... 0.5

(Print or Type Responses)
1. Name and Address of Reporting Person *
Carestio Daniel A
  2. Issuer Name and Ticker or Trading Symbol
Steris plc [STE]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Sr. V. P., Isomedix & Life Sci
(Last)
(First)
(Middle)
C/O CHANCERY HOUSE, 190 WATERSIDE ROAD, HAMILTON INDUSTRIAL PARK
3. Date of Earliest Transaction (Month/Day/Year)
12/08/2016
(Street)

LEICESTER, X0 LE5 1QZ
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Ordinary Shares, 0.10 par value 12/08/2016   M   2,225 A $ 29.94 20,025 D  
Ordinary Shares, 0.10 par value 12/08/2016   S   2,225 D $ 67.5383 (1) 17,800 (2) D  

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number. SEC 1474 (9-02)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Employee Stock Option (right to buy) $ 29.94 12/08/2016   M     2,225   (3) 05/30/2022 Ordinary Shares, 0.10 2,225 (3) 0 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
Carestio Daniel A
C/O CHANCERY HOUSE, 190 WATERSIDE ROAD
HAMILTON INDUSTRIAL PARK
LEICESTER, X0 LE5 1QZ
      Sr. V. P., Isomedix & Life Sci  

Signatures

 /s/ Ronald E. Snyder, Authorized Representative under Power of Attorney   12/09/2016
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) This represents the average sales price of the 2,225 shares sold in the open market. The actual sales prices ranged from $67.50 per share to $67.72 per share. Issuer, upon request by the SEC staff, will provide full information regarding the number of shares sold at each of these eight sales prices.
(2) 17,800 of these ordinary shares are restricted. The restrictions on these ordinary shares lapse as follows: 3,300 on May 31, 2017; 4,000 on May 30, 2018, 5,000 on May 28, 2019, 3,000 on October 1, 2019 and 2,500 on June 1, 2020.
(3) This option is fully exercisable. This option was received in the merger in exchange for an option to purchase 2,225 STERIS common shares for $29.94 per share, subject to the same terms and conditions as the original STERIS stock option.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.