Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0104
Expires: January 31, 2005
Estimated average burden hours per response... 0.5

(Print or Type Responses)
1. Name and Address of Reporting Person *
  MISYS PLC
 2. Date of Event Requiring Statement (Month/Day/Year)
10/10/2008		 3. Issuer Name and Ticker or Trading Symbol
ALLSCRIPTS-MISYS HEALTHCARE SOLUTIONS, INC. [MDRX]
(Last)
(First)
(Middle)
ONE KINGDOM STREET, PADDINGTON		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

LONDON, X0 W2 6BL		 6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock, $0.01 par value 82,886,017 (1)
I
by Misys plc (1)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
MISYS PLC
ONE KINGDOM STREET
PADDINGTON
LONDON, X0 W2 6BL		     X    
MISYS HOLDINGS INC
103 FOULK ROAD, SUITE 202
WILMINGTON, DE 19803		     X    
MISYS PATRIOT US HOLDINGS LLC
103 FOULK ROAD, SUITE 202
WILMINGTON, DE 19803		     X    
MISYS PATRIOT LTD
ONE KINGDOM STREET
PADDINGTON
LONDON, X0 W2 6BL		     X    

Signatures

Misys plc by: /s/ James C. Malone 10/20/2008
**Signature of Reporting Person Date
Misys Holdings Inc. by: /s/ Darryl E. Smith 10/20/2008
**Signature of Reporting Person Date
Misys Patriot US Holdings LLC by: /s/ Darryl E. Smith 10/20/2008
**Signature of Reporting Person Date
Misys Patriot Ltd. by: /s/ Glyn Fullelove 10/20/2008
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Misys plc is the indirect owner of 82,886,017 shares of common stock, par value $0.01, of Allscripts-Misys Healthcare Solutions, Inc. ("AM") through its wholly-owned subsidiaries, Misys Patriot Ltd. and Misys Patriot US Holdings LLC, which directly own 18,857,142 and 64,028,875 shares, respectively. On 10/10/2008, pursuant to the Agreement and Plan of Merger, dated as of 3/17/2008, between Misys plc ("Misys"), Allscripts Healthcare Solutions, Inc., Misys Healthcare Systems, LLC and Patriot Merger Company, LLC, Misys Patriot Ltd., a wholly-owned subsidiary of Misys, acquired 18,857,142 shares of common stock, par value $0.01, of Allscripts-Misys Healthcare Solutions, Inc. ("AM"), and Misys Holdings Inc. ("MHI"), a wholly-owned subsidiary of Misys, acquired 64,028,875 shares (the "MHI Shares") of common stock, par value $0.01 of AM. On 10/10/2008, MHI made a capital contribution to MPUSH of all of the MHI Shares in a transfer exempt under Rule 16a-13.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, See Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.