Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Expires: January 31, 2005
Estimated average burden hours per response... 0.5

(Print or Type Responses)
1. Name and Address of Reporting Person *
Rosebrough Walter M Jr
  2. Issuer Name and Ticker or Trading Symbol
STERIS CORP [STE]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
President & CEO
(Last)
(First)
(Middle)
5960 HEISLEY ROAD
3. Date of Earliest Transaction (Month/Day/Year)
10/01/2010
(Street)

MENTOR, OH 44060
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Shares, No Par Value 10/01/2010   S(1)   2,600 D $ 33.2401 109,400 D  
Common Shares, No Par Value 10/01/2010   S(2)   9,000 D $ 33.0373 100,400 D  
Common Shares, No Par Value 10/01/2010   M(3)   11,000 A $ 33.43 111,400 D  
Common Shares, No Par Value 10/01/2010   M(4)   12,000 A $ 33.43 123,400 (5) D  

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number. SEC 1474 (9-02)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Conversion of Restricted Stock Units (6) 10/01/2010   M     11,000   (7)   (7) Common Shares, No Par Value 11,000 $ 0 0 D  
Conversion of Restricted Stock Units (6) 10/01/2010   M     12,000   (8)   (8) Common Shares, No Par Value 12,000 $ 0 0 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
Rosebrough Walter M Jr
5960 HEISLEY ROAD
MENTOR, OH 44060
  X     President & CEO  

Signatures

 Dennis P. Patton, Authorized Representative under Power of Attorney   10/01/2010
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) This open market sale of a total of 2,600 Common Shares is for the purpose of providing for the taxes payable upon the vesting of 23,000 restricted stock units and is made pursuant to a Rule 10b5-1 Stock Trading Plan entered into by the Reporting Person on May 9, 2010.
(2) This open market sale of a total of 9,000 Common Shares is for the purpose of providing for the taxes payable upon the vesting of 23,000 restricted stock units and is made pursuant to a Rule 10b5-1 Stock Trading Plan entered into by the Reporting Person on May 9, 2010.
(3) This acquisition of 11,000 Common Shares represents the vesting on October 1, 2010 of 11,000 Restricted Stock Units granted pursuant to an agreement effective October 15, 2007.
(4) This acquisition of 12,000 Common Shares represents the vesting on October 1, 2010 of 12,000 Restricted Stock Units granted pursuant to an agreement effective October 15, 2007.
(5) 83,000 of these Common Shares are restricted. The restrictions on these Common Shares lapse as follows: 24,000 on May 23, 2011, 24,000 on May 21, 2012 and 35,000 on May 20, 2014.
(6) Each Restricted Stock Unit represents a contingent right to receive one STERIS Common Share.
(7) These Restricted Stock Units vested on October 1, 2010. The 11,000 vested Common Shares will be delivered to the reporting person promptly.
(8) These Restricted Stock Units vested on October 1, 2010. The 12,000 vested Common Shares will be delivered to the reporting person promptly.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.