Ownership Submission
FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0104
Expires: January 31, 2005
Estimated average burden hours per response... 0.5

(Print or Type Responses)
1. Name and Address of Reporting Person *
  Michael A Kelly
2. Date of Event Requiring Statement (Month/Day/Year)
08/10/2005
3. Issuer Name and Ticker or Trading Symbol
AMGEN INC [AMGN]
(Last)
(First)
(Middle)
ONE AMGEN CENTER DRIVE
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
VP Corp Plng & Control & CAO
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

THOUSAND OAKS, CA 91320-1799
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock (1) 4,800
D
 
Common Stock 50
I
Michael & Bonnie Kelly Family Trust

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
ISO (Right to buy) 02/10/2004(2) 02/10/2010 Common Stock 3,774 $ 52.98 D  
ISO (Right to buy) 03/15/2009 03/15/2011 Common Stock 1,681 $ 59.48 D  
ISO (Right to buy) 07/01/2008 07/01/2010 Common Stock 1,518 $ 65.85 D  
NQSO (Right to Buy) 02/10/2004(3) 02/10/2010 Common Stock 27,452 $ 52.98 D  
NQSO (Right to Buy) 03/16/2005(4) 03/16/2012 Common Stock 8,500 $ 58.61 D  
NQSO (Right to Buy) 03/15/2005(5) 03/15/2011 Common Stock 9,851 $ 59.48 D  
NQSO (Right to Buy) 07/01/2004(6) 07/01/2010 Common Stock 14,482 $ 65.85 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Michael A Kelly
ONE AMGEN CENTER DRIVE
THOUSAND OAKS, CA 91320-1799
      VP Corp Plng & Control & CAO  

Signatures

/s/ Michael A. Kelly 08/10/2005
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Of the total, 4,700 shares were issued pursuant to Amended and Restated 1991 Equity Incentive Plan.
(2) This option is exercisable on February 10, 2006 for 1,887 shares and on February 10, 2007 for 1,887 shares.
(3) (MAK 2.10.03) This option is exercisable in four equal installments each beginning February 10, 2004.
(4) (MAK 3.15.05) This option is exercisable in four equal installments beginning March 15, 2006.
(5) (MAK 3.15.04) This option is exercisable as follows: 2,306 shares each on March 15, 2005 and on March 15, 2006; 2,307 shares on March 15, 2007; 2,306 shares on March 15, 2008; and 626 shares on March 15, 2009.
(6) (MAK 7.1.03) This option is exercisable in four equal installments of 3,200 beginning July 1, 2004 and a final installment on July 1, 2008 of 1, 682 shares.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, See Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.