Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
| [] | Rule 13d-1(b) |
| [X] | Rule 13d-1(c) |
| [] | Rule 13d-1(d) |
|
The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page. The information required in the remainder of this cover page shall not be deemed to be 'filed' for the purpose of Section 18 of the Securities Exchange Act of 1934 ('Act') or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes). |
| CUSIP No. 98973P101 | ||||
| Person 1 | ||||
| 1. | (a) Names of Reporting Persons. Henderson Group PLC, Henderson Global Investors (Holdings) PLC, Henderson Global Investors Limited | |||
| (b) Tax ID | ||||
| 2. | Check the Appropriate Box if a Member of a Group (See Instructions) | |||
| (a) [] | ||||
| (b) [] | ||||
| 3. | SEC Use Only . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . | |||
| 4. | Citizenship or Place of Organization United Kingdom | |||
| Number of Shares Beneficially Owned by Each Reporting Person With | ||||
| 5. Sole Voting Power 0 | ||||
| 6. Shared Voting Power 300,920 | ||||
| 7. Sole Dispositive Power 0 | ||||
| 8. Shared Dispositive Power 300,920 | ||||
| 9. | Aggregate Amount Beneficially Owned by Each Reporting Person 300,920 | |||
| 10. | Check if the Aggregate Amount in Row (9) Excludes Certain Shares (See Instructions) | |||
| 11. | Percent of Class Represented by Amount in Row (9) 1.18% | |||
| 12. | Type of Reporting Person (See Instructions) | |||
| HC | ||||
| Item 1. | ||||||
| (a) | Name of Issuer Ziopharm Oncology Inc | |||||
| (b) | Address of Issuer's Principal Executive Offices | |||||
| 197 Eighth Street, Suite 300, Charlestown, MA 02329 | ||||||
| Item 2. | ||||||
| (a) | Name of Person Filing Henderson Group PLC, Henderson Global Investors (Holdings) PLC, Henderson Global Investors Limited | |||||
| (b) | Address of Principal Business Office or, if none, Residence 201 Bishopsgate, London EC2M 3AE, UK | |||||
| (c) | Citizenship United Kingdom | |||||
| (d) | Title of Class of Securities Common Stock Par Value $0.001 |
|||||
| (e) | CUSIP Number 98973P101 | |||||
| Item 3. | If this statement is filed pursuant to 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a: | |
| (a) | [ ] | Broker or dealer registered under section 15 of the Act (15 U.S.C. 78c) |
| (b) | [ ] | Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c). |
| (c) | [ ] | Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c). |
| (d) | [ ] | Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C 80a-8). |
| (e) | [ ] | An investment adviser in accordance with 240.13d-1(b)(1)(ii)(E); |
| (f) | [ ] | An employee benefit plan or endowment fund in accordance with 240.13d-1(b)(1)(ii)(F); |
| (g) | [ ] | A parent holding company or control person in accordance with 240.13d-1(b)(1)(ii)(G); |
| (h) | [ ] | A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813); |
| (i) | [ ] | A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3); |
| (j) | [ ] | A non-U.S. institution in accordance with 240.13d-1(b)(1)(ii)(J);. |
| (k) | [ ] | Group, in accordance with 240.13d-1(b)(1)(ii)(K).If filing as a non-U.S. institution in accordance with 240.13d-1(b)(ii)(J), please specify the type of institution: |
| Item 4. | Ownership. | |||
| Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1. | ||||
| (a) | Amount beneficially owned: 300,920 | |||
| (b) | Percent of class: 0% | |||
| (c) | Number of shares as to which the person has: | |||
| (i) | Sole power to vote or to direct the vote 0 | |||
| (ii) | Shared power to vote or to direct the vote 300,920 | |||
| (iii) | Sole power to dispose or to direct the disposition of 0 | |||
| (iv) | Shared power to dispose or to direct the disposition of 300,920 | |||
| Item 5. | Ownership of Five Percent or Less of a Class | |||
| If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following.[X ]. | ||||
| Item 6. | Ownership of More than Five Percent on Behalf of Another Person. | |||
| Item 7. | Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person. | |||
| Item 8. | Identification and Classification of Members of the Group | |||
| Item 9. | Notice of Dissolution of Group | |||
| Item 10. | Certification | |||
|
By signing below I certify that, to the best of my knowledge
and belief, the securities referred to above were not acquired and are not held
for the purpose of or with the effect of changing or influencing the control of
the issuer of the securities and were not acquired and are not held in
connection with or as a participant in any transaction having that purpose or
effect. | ||||
| After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct. |
| February 12, 2010 | Date |
| /s/ Brian Rowe | Signature |
| Brian Rowe/Global Head of Compliance |
| Name/Title |
| Exhibit A |
| AGREEMENT REGARDING JOINT FILING The undersigned, Henderson Group PLC, Henderson Global Investors (Holdings) PLC and Henderson Global Investors limited, hereby agree and acknowledge that the statement containing the information required by Schedule 13G, to which this Agreement is attached as an exhibit, is filed on behalf of each of them. The undersigned further agree that any amendments or supplements thereto shall also be filed on behalf of each of them. Henderson Group PLC Date February 12, 2010 By /s/ Brian Rowe Name: Brian Rowe Title: Global Head of Compliance Henderson Global Investors (Holdings) PLC Date February 12, 2010 By /s/ Brian Rowe Name: Brian Rowe Title: Global Head of Compliance Henderson Global Investors Limited Date February 12, 2010 By /s/ Brian Rowe Name: Brian Rowe Title: Global Head of Compliance |
| Attention: | Intentional misstatements or omissions of fact constitute Federal
criminal violations (See 18 U.S.C. 1001) |
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