FORM 10-Q
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 10-Q
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þ |
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QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 |
For
the quarterly period ended December 31, 2006
OR
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o |
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TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 |
Commission file number: 001-04389
APPLERA CORPORATION
(Exact Name of Registrant as Specified in Its Charter)
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Delaware
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06-1534213 |
(State or Other Jurisdiction of
Incorporation or Organization)
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(I.R.S. Employer
Identification No.) |
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301 Merritt 7, Norwalk, Connecticut
(Address of Principal Executive Offices)
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06851-1070
(Zip Code) |
(203) 840-2000
(Registrants Telephone Number, Including Area Code)
Indicate by check mark whether the registrant (1) has filed all reports required to be filed by
Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for
such shorter period that the registrant was required to file such reports), and (2) has been
subject to such filing requirements for the past 90 days.
Yes þ No o
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer,
or a non-accelerated filer. See definition of accelerated filer and large accelerated filer in
Rule 12b-2 of the Exchange Act. (Check one):
Large accelerated filer
þ Accelerated filer o Non-accelerated filer o
Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the
Exchange Act).
Yes o No þ
As of the close of business on February 5, 2007, there were 183,551,517 shares of Applera
Corporation-Applied Biosystems Group Common Stock and 78,547,743 shares of Applera Corporation-Celera Group
Common Stock outstanding.
APPLERA CORPORATION
INDEX
PART I FINANCIAL INFORMATION
Item 1. Financial Statements.
APPLERA CORPORATION
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
(unaudited)
(Dollar amounts in thousands except per share amounts)
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Three Months Ended |
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Six Months Ended |
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December 31, |
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December 31, |
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2006 |
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2005 |
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2006 |
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2005 |
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Products |
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$ |
442,846 |
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$ |
403,109 |
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$ |
833,928 |
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$ |
741,638 |
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Services |
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60,782 |
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55,189 |
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118,922 |
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107,456 |
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Other |
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38,221 |
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31,389 |
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74,408 |
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62,821 |
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Total Net Revenues |
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541,849 |
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489,687 |
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1,027,258 |
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911,915 |
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Products |
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209,802 |
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194,869 |
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406,461 |
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363,076 |
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Services |
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26,539 |
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24,582 |
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51,137 |
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48,571 |
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Other |
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3,055 |
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3,425 |
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5,882 |
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7,059 |
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Total Cost of Sales |
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239,396 |
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222,876 |
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463,480 |
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418,706 |
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Gross Margin |
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302,453 |
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266,811 |
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563,778 |
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493,209 |
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Selling, general and administrative |
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154,842 |
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144,619 |
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297,227 |
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276,484 |
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Research, development and
engineering |
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62,160 |
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73,077 |
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120,062 |
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142,774 |
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Amortization of purchased
intangible assets |
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2,842 |
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680 |
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5,579 |
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1,719 |
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Employee-related charges, asset
impairments and other |
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2,513 |
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360 |
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6,013 |
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1,231 |
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Asset dispositions and legal
settlements |
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(10,145 |
) |
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3,032 |
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(1,058 |
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26,541 |
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Acquired research and development |
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114,251 |
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Operating Income |
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90,241 |
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45,043 |
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21,704 |
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44,460 |
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Gain on investments, net |
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209 |
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4,503 |
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Interest expense |
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193 |
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(78 |
) |
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(304 |
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(165 |
) |
Interest income |
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10,152 |
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9,233 |
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19,862 |
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18,990 |
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Other income (expense), net |
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1,039 |
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1,001 |
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2,456 |
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2,708 |
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Income before Income Taxes |
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101,625 |
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55,199 |
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43,927 |
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70,496 |
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Provision for income taxes |
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27,136 |
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41,114 |
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35,450 |
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31,232 |
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Net Income |
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$ |
74,489 |
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$ |
14,085 |
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$ |
8,477 |
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$ |
39,264 |
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Applied Biosystems Group (see Note
4) |
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Net Income per Share |
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Basic |
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$ |
0.41 |
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$ |
0.17 |
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$ |
0.09 |
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$ |
0.38 |
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Diluted |
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$ |
0.39 |
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$ |
0.17 |
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$ |
0.08 |
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$ |
0.38 |
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Dividends Declared per Share |
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$ |
0.0425 |
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$ |
0.0425 |
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$ |
0.0850 |
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$ |
0.0850 |
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Celera Group (see Note 4) |
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Net Loss per Share |
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Basic and diluted |
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$ |
(0.01 |
) |
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$ |
(0.23 |
) |
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$ |
(0.10 |
) |
|
$ |
(0.46 |
) |
See accompanying notes to the Applera Corporation unaudited condensed consolidated financial
statements.
1
APPLERA CORPORATION
CONDENSED CONSOLIDATED STATEMENTS OF FINANCIAL POSITION
(unaudited)
(Dollar amounts in thousands)
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At December 31, |
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At June 30, |
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2006 |
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2006 |
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Assets |
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Current assets |
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Cash and cash equivalents |
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$ |
319,345 |
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$ |
434,191 |
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Short-term investments |
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591,265 |
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509,252 |
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Accounts receivable, net |
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389,336 |
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382,509 |
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Inventories, net |
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151,449 |
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137,651 |
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Prepaid expenses and other current assets |
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169,228 |
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163,362 |
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Total current assets |
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1,620,623 |
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1,626,965 |
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Property, plant and equipment, net |
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389,999 |
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396,436 |
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Goodwill and intangible assets, net |
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314,058 |
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322,097 |
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Other long-term assets |
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665,768 |
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667,477 |
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Total Assets |
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$ |
2,990,448 |
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$ |
3,012,975 |
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Liabilities and Stockholders Equity |
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Current liabilities |
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Accounts payable |
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$ |
169,011 |
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$ |
201,691 |
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Accrued salaries and wages |
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72,229 |
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98,938 |
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Current deferred tax liability |
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17,045 |
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17,560 |
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Accrued taxes on income |
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36,314 |
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50,944 |
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Other accrued expenses |
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242,734 |
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239,157 |
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Total current liabilities |
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537,333 |
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|
608,290 |
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Other long-term liabilities |
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209,845 |
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200,351 |
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Total Liabilities |
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747,178 |
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|
808,641 |
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Stockholders Equity |
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Capital stock |
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Applera CorporationApplied Biosystems Group |
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2,133 |
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|
2,132 |
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Applera CorporationCelera Group |
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|
784 |
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|
773 |
|
Capital in excess of par value |
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|
2,218,062 |
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2,192,559 |
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Retained earnings |
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|
717,379 |
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|
714,137 |
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Accumulated other comprehensive income |
|
|
51,291 |
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|
40,947 |
|
Treasury stock, at cost |
|
|
(746,379 |
) |
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(746,214 |
) |
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|
|
|
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Total Stockholders Equity |
|
|
2,243,270 |
|
|
|
2,204,334 |
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|
|
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Total Liabilities and Stockholders Equity |
|
$ |
2,990,448 |
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$ |
3,012,975 |
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|
|
|
|
|
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|
See accompanying notes to the Applera Corporation unaudited condensed consolidated financial
statements.
2
APPLERA CORPORATION
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
(Unaudited)
(Dollar amounts in thousands)
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Six months ended |
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December 31, |
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|
2006 |
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2005 |
|
Operating Activities of Continuing Operations |
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Net income |
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$ |
8,477 |
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$ |
39,264 |
|
Adjustments to reconcile net income to net cash
provided by operating activities: |
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|
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Depreciation and amortization |
|
|
42,646 |
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|
46,048 |
|
Asset impairments |
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3,000 |
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|
1,090 |
|
Employee-related charges and other |
|
|
3,013 |
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(1,409 |
) |
Share-based compensation programs |
|
|
8,895 |
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|
4,437 |
|
Sale of assets and legal settlements, net |
|
|
(209 |
) |
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|
22,938 |
|
Deferred income taxes |
|
|
709 |
|
|
|
(6,327 |
) |
Acquired research and development |
|
|
114,251 |
|
|
|
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Changes in operating assets and liabilities: |
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Accounts receivable |
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|
(2,538 |
) |
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|
31,394 |
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Inventories |
|
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(11,033 |
) |
|
|
(7,626 |
) |
Prepaid expenses and other assets |
|
|
(13,500 |
) |
|
|
(2,408 |
) |
Accounts payable and other liabilities |
|
|
(45,144 |
) |
|
|
(2,762 |
) |
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|
Net Cash Provided by Operating Activities
of Continuing Operations |
|
|
108,567 |
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|
124,639 |
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Investing Activities of Continuing Operations |
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Additions to property, plant and equipment, net |
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|
(28,451 |
) |
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|
(25,747 |
) |
Proceeds from maturities of available-for-sale investments |
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|
130,745 |
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|
75,983 |
|
Proceeds from sales of available-for-sale investments |
|
|
277,608 |
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|
|
227,145 |
|
Purchases of available-for-sale investments |
|
|
(487,771 |
) |
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|
(250,100 |
) |
Acquisitions and investments |
|
|
(121,403 |
) |
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|
(1,235 |
) |
Proceeds from the sale of assets, net |
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|
322 |
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|
|
4,503 |
|
|
|
|
|
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Net Cash
Provided (Used) by Investing Activities
of Continuing Operations |
|
|
(228,950 |
) |
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|
30,549 |
|
|
|
|
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Financing Activities |
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|
|
|
|
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Dividends |
|
|
(15,411 |
) |
|
|
(8,253 |
) |
Purchases of common stock for treasury |
|
|
(59,856 |
) |
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|
(457,120 |
) |
Proceeds from stock issued for stock plans and other |
|
|
74,584 |
|
|
|
70,432 |
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|
|
|
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|
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Net Cash Used by Financing Activities |
|
|
(683 |
) |
|
|
(394,941 |
) |
|
|
|
|
|
|
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Effect of Exchange Rate Changes on Cash |
|
|
6,220 |
|
|
|
(8,668 |
) |
|
|
|
|
|
|
|
Net Change in Cash and Cash Equivalents |
|
|
(114,846 |
) |
|
|
(248,421 |
) |
Cash and Cash Equivalents Beginning of Period |
|
|
434,191 |
|
|
|
779,401 |
|
|
|
|
|
|
|
|
Cash and Cash Equivalents End of Period |
|
$ |
319,345 |
|
|
$ |
530,980 |
|
|
|
|
|
|
|
|
See accompanying notes to the Applera Corporation unaudited condensed consolidated financial
statements.
3
APPLERA CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
Note 1 Interim Condensed Consolidated Financial Statements
Basis of Presentation
We prepare our unaudited interim condensed consolidated financial statements and related
disclosures in conformity with accounting principles generally accepted in the United States of
America, or GAAP. In preparing these statements, we are required to use estimates and assumptions.
While we believe we have considered all available information, actual results could affect the
reported amounts of assets and liabilities, disclosure of contingent assets and liabilities at the
date of the financial statements, and the reported amounts of revenues and expenses during the
reporting period. The results for the interim periods are not necessarily indicative of trends or
future financial results. When used in these notes, the terms Applera, Company, we, us, or
our mean Applera Corporation and its subsidiaries.
Through December 31, 2005, we were comprised of three business segments: the Applied Biosystems
group, the Celera group, and Celera Diagnostics, a 50/50 joint venture between the Applied
Biosystems group and the Celera group. Effective December 1, 2006, we changed the name of our
Celera Genomics group to Celera group to better reflect the Celera groups focus and business
strategy. Effective January 1, 2006, the Celera group acquired the Applied Biosystems groups 50
percent interest in the Celera Diagnostics joint venture such that it now owns 100 percent of
Celera Diagnostics. As a result of this restructuring and the manner by which our management now
operates and assesses our businesses, Celera Diagnostics is no longer a separate segment within
Applera and we have restated prior period consolidating financial information to reflect this
change. See Note 15 to our consolidated financial statements included in our 2006 Annual Report to
Stockholders for a detailed description of the Celera Diagnostic restructuring.
We consistently applied the accounting policies described in our 2006 Annual Report to Stockholders
in preparing these unaudited interim financial statements. We made all adjustments that are
necessary, in our opinion, for a fair statement of the results for the interim periods. These
adjustments are of a normal recurring nature. We condensed or omitted from these interim financial
statements several notes and other information included in our 2006 Annual Report to Stockholders.
You should read these unaudited interim condensed consolidated financial statements in conjunction
with our consolidated financial statements presented in our 2006 Annual Report to Stockholders. We
have reclassified some prior year amounts in the condensed consolidated financial statements and
notes for comparative purposes.
Recently Issued Accounting Pronouncements
In September 2006, the Financial Accounting Standards Board (FASB) issued Statement of Financial
Accounting Standards (SFAS) No. 157, Fair Value Measurements. SFAS No. 157 defines fair value,
establishes a framework for measuring fair value under GAAP, and expands disclosures about fair
value measurements. The provisions of SFAS No. 157 are effective for our 2009 fiscal year
beginning July 1, 2008, and interim periods within that fiscal year. We are currently evaluating
the provisions of SFAS No. 157 and the resulting impact of adoption on our financial statements.
Also in September 2006, the FASB issued SFAS No. 158, Employers Accounting for Defined Benefit
Pension and Other Postretirement Plans, an amendment of FASB Statements No. 87, 88, 106, and
132(R). SFAS No. 158 requires an employer to recognize the overfunded or underfunded status of a
defined benefit postretirement plan as an asset or liability in its statement of financial position
and recognize changes in the funded status in the year in which the changes occur through
comprehensive income. The recognition and disclosure provisions of SFAS No. 158 are effective for
our fiscal year ending June 30, 2007. Since we measure plan assets and obligations on an annual
basis, we can not estimate the impact of SFAS No. 158 in advance of our June 30, 2007 measurement
date. The amount we will record in our statement of financial position related to this Statement
depends on numerous future events and circumstances, such as the assumptions used to value our
pension plan liabilities and determine future funding requirements
Also in September 2006, the Securities and Exchange Commission staff issued Staff Accounting
Bulletin (SAB) No. 108, Considering the Effects of Prior Year Misstatements when Quantifying
Misstatements in Current Year Financial
Statements. SAB 108 established an approach that requires quantification of financial statement
errors based on the effects of an error on a companys balance sheet and income statement and
related disclosures. Historically, we have used the rollover approach for quantifying identified
financial statement misstatements. This approach quantifies misstatements based on the amount of
the error originating in the current year. We are required to apply the provisions of SAB 108 in
connection with the preparation of our annual financial statements for our fiscal year ended June
30, 2007.
4
APPLERA CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
continued
We are currently evaluating the provisions of SAB 108 but do not expect the resulting impact of
adoption to have a material impact on our financial statements.
Note 2 Events Impacting Comparability
We are providing the following information on some actions taken by us or events that occurred in
the periods indicated:
|
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|
|
|
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|
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|
|
|
|
Three months ended |
|
Six months ended |
Income/(charge) |
|
December 31, |
|
December 31, |
(Dollar amounts in millions) |
|
2006 |
|
2005 |
|
2006 |
|
2005 |
|
Severance and benefit costs |
|
$ |
|
|
|
$ |
(1.5 |
) |
|
$ |
|
|
|
$ |
(1.5 |
) |
Asset impairments |
|
|
(3.0 |
) |
|
|
|
|
|
|
(3.0 |
) |
|
|
(1.1 |
) |
Other |
|
|
(0.1 |
) |
|
|
|
|
|
|
(3.6 |
) |
|
|
|
|
Reduction of expected costs |
|
|
0.6 |
|
|
|
1.2 |
|
|
|
0.6 |
|
|
|
1.4 |
|
|
Total employee-related charges, asset impairments and other |
|
$ |
(2.5 |
) |
|
$ |
(0.3 |
) |
|
$ |
(6.0 |
) |
|
$ |
(1.2 |
) |
|
Other events impacting comparability: |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Revenue from sale of small molecule program |
|
$ |
2.5 |
|
|
$ |
|
|
|
$ |
2.5 |
|
|
$ |
|
|
Asset dispositions and legal settlements |
|
|
10.2 |
|
|
|
(3.1 |
) |
|
|
1.1 |
|
|
|
(26.6 |
) |
Acquired research and development |
|
|
|
|
|
|
|
|
|
|
(114.3 |
) |
|
|
|
|
Investment gains |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
4.5 |
|
Tax items |
|
|
1.0 |
|
|
|
(28.0 |
) |
|
|
9.8 |
|
|
|
(14.5 |
) |
|
Employee-Related Charges, Asset Impairments and Other
The following items have been recorded in the condensed consolidated statements of operations in
employee-related charges, asset impairments and other, except as noted.
Applied Biosystems group
Fiscal 2006
In the second quarter of fiscal 2006, the Applied Biosystems group recorded pre-tax charges of $1.5
million for employee terminations related to the Applied Biosystems/MDS Sciex Instruments joint
venture, a 50/50 joint venture between the Applied Biosystems group and MDS Inc. MDS recorded a
restructuring charge for a reduction in workforce as part of its strategy to focus on the life
sciences market. The $1.5 million represented the Applied Biosystems groups share of the
restructuring charge.
The Applied Biosystems group recorded pre-tax benefits of $1.2 million in the second quarter and
$1.4 million in the first six months of fiscal 2006 for reductions in anticipated employee-related
costs associated with severance and benefit charges recorded in fiscal 2005.
In the first quarter of fiscal 2006, the Applied Biosystems group recorded a $1.1 million pre-tax
impairment charge to write-down the carrying amount of its San Jose, California facility to its
estimated market value at that time less estimated selling costs. This charge was in addition to a
charge recorded in fiscal 2005. In the fourth quarter of fiscal 2006, the Applied Biosystems group
completed the sale and recognized a $0.9 million pre-tax favorable adjustment to the charges
previously recorded based on the actual sales price.
Other fiscal
2007 cash payments
During the first six months of fiscal 2007, the Applied Biosystems group made cash payments of $0.8
million for severance and employee benefits and office closures related to charges recorded prior
to fiscal 2006. The following table summarizes the remaining cash payments by event and the
expected payment dates as of December 31, 2006.
5
APPLERA CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
continued
|
|
|
|
|
|
|
|
|
(Dollar amounts in millions) |
Remaining cash payments |
|
|
Expected payment dates |
|
Fiscal 2003 employee-related charge |
|
$ |
0.3 |
|
|
Fiscal 2008 |
Fiscal 2005 employee-related charge |
|
|
0.1 |
|
|
Fiscal 2007 |
Fiscal 2005 excess lease space and other charges |
|
|
1.1 |
|
|
Fiscal 2007 Fiscal 2011 |
|
|
|
|
|
$ |
1.5 |
|
|
|
|
|
|
Celera group
Fiscal 2007
During the second quarter of fiscal 2007, the Celera group recorded a pre-tax charge of $2.5
million, which was primarily comprised of a $3.0 million pre-tax charge for the write-down of the
carrying amount of an owned facility that was impaired initially in fiscal 2006, partially offset
by a pre-tax benefit of $0.6 million for a reduction in anticipated employee-related costs
associated with severance and benefit charges recorded in the third and fourth quarters of fiscal
2006. Both of these items are discussed below.
During the first quarter of fiscal 2007, the Celera group recorded a pre-tax charge of $3.5 million
for its estimated share of a damage award in continuing litigation between Abbott Laboratories, our
alliance partner, and Innogenetics N.V. In September 2006, a jury found that the sale of hepatitis
C virus (HCV) genotyping analyte specific reagents (ASRs) products by Abbott willfully
infringed a U.S. patent owned by Innogenetics and awarded Innogenetics $7.0 million in damages. In
January 2007, the U.S. District Court for the Western District of Wisconsin ruled in favor of
Innogenetics request for a permanent injunction, and as such, ordered Abbott to withdraw its
products from the market. The Court also reversed the jury verdict of willful infringement and
ruled that Abbott did not willfully infringe Innogenetics patent and denied Innogenetics request
for enhanced damages and attorneys fees. Innogenetics did not name the Celera group as a party in
this lawsuit, but the Celera group has an interest in these products and in the outcome of the
litigation because the enjoined products are manufactured by the Celera group and sold through its
alliance with Abbott. Also, as these products are part of its alliance with Abbott, the Celera
group has agreed to share the cost of this litigation, including the damage award described above.
Abbott has informed the Celera group that it will appeal the judgment as both Abbott and the Celera
group believe that Innogenetics patent is invalid and that the alliances HCV genotyping ASRs do
not infringe Innogenetics patent. Abbott has filed an emergency motion with the Court of Appeals
for the Federal Circuit seeking a stay of the permanent injunction during the appeal process.
Also, on January 19, 2007, Abbott obtained a temporary stay of the injunction from the Court
pending the Courts consideration of the emergency motion for a stay of the permanent injunction.
6
APPLERA CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
continued
Fiscal 2006
During fiscal 2006, the Celera group recorded pre-tax charges related to its decision to exit its
small molecule drug discovery and development programs and the integration of Celera Diagnostics
into the Celera group. These charges consisted of the following components:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Employee- |
|
|
|
|
|
|
Excess |
|
|
Other |
|
|
|
|
|
|
Related |
|
|
Asset |
|
|
Lease |
|
|
Disposal |
|
|
|
|
(Dollar amounts in millions) |
|
Charges |
|
|
Impairments |
|
|
Space |
|
|
Costs |
|
|
Total |
|
|
Third quarter |
|
$ |
10.7 |
|
|
$ |
8.0 |
|
|
$ |
0.8 |
|
|
$ |
1.4 |
|
|
$ |
20.9 |
|
Fourth quarter |
|
|
2.1 |
|
|
|
1.8 |
|
|
|
0.4 |
|
|
|
1.2 |
|
|
|
5.5 |
|
|
Total charges |
|
|
12.8 |
|
|
|
9.8 |
|
|
|
1.2 |
|
|
|
2.6 |
|
|
|
26.4 |
|
|
Cash payments |
|
|
7.9 |
|
|
|
|
|
|
|
0.2 |
|
|
|
2.4 |
|
|
|
10.5 |
|
Non-cash activity |
|
|
|
|
|
|
9.3 |
|
|
|
|
|
|
|
0.2 |
|
|
|
9.5 |
|
|
Balance at June 30, 2006 |
|
|
4.9 |
|
|
|
0.5 |
|
|
|
1.0 |
|
|
|
|
|
|
|
6.4 |
|
|
Additional charge |
|
|
|
|
|
|
3.0 |
|
|
|
|
|
|
|
|
|
|
|
3.0 |
|
|
Non-cash activity |
|
|
|
|
|
|
3.0 |
|
|
|
|
|
|
|
|
|
|
|
3.0 |
|
Cash payments |
|
|
4.1 |
|
|
|
|
|
|
|
0.7 |
|
|
|
|
|
|
|
4.8 |
|
Reduction of expected costs |
|
|
0.6 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
0.6 |
|
|
Balance at December 31, 2006 |
|
$ |
0.2 |
|
|
$ |
0.5 |
|
|
$ |
0.3 |
|
|
$ |
|
|
|
$ |
1.0 |
|
|
The employee-related charges were severance costs primarily for staff reductions in small molecule
drug discovery and development. All of the affected employees were notified and terminated by
September 30, 2006. In the second quarter of fiscal 2007, the Celera group recorded a pre-tax
benefit of $0.6 million for a reduction in anticipated employee-related costs associated with the
severance and benefit charges recorded in the third and fourth quarters of fiscal 2006.
The asset impairment charges primarily related to a write-down of the carrying amount of an owned
facility to its current estimated market value less estimated selling costs, as well as write-offs
of leasehold improvements and equipment. This facility was reclassified into assets held for sale
in fiscal 2006. In the second quarter of fiscal 2007, the Celera group recorded an additional $3.0
million pre-tax, non-cash charge to write-down the carrying amount of this facility.
Cash expenditures for these charges were funded by available cash. The remaining cash expenditures
related to these charges are expected to be disbursed by December 31, 2007.
Other fiscal 2007 cash payments
During the first six months of fiscal 2007, the Celera group made net cash payments of
approximately $0.8 million related to an excess facility lease space charge that was recorded prior
to fiscal 2006. The remaining net cash expenditures of approximately $3.5 million related to this
charge, which reflected an adjustment in the second quarter of fiscal 2007, are expected to be
disbursed by fiscal 2011.
Other Events Impacting Comparability
Revenue from sale of small molecule program
In the second quarter of fiscal 2007, the Celera group recorded a pre-tax gain of $2.5 million in
net revenues from the sale of a small molecule drug discovery and development program to Schering
AG, which represented the remaining balance for this transaction. The Celera group recorded $2.5
million in the fourth quarter of fiscal 2006 when the agreement for
the sale of the program was executed.
Asset dispositions and legal settlements
The following items have been recorded in the condensed consolidated statements of operations in
asset dispositions and legal settlements.
7
APPLERA CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
continued
Fiscal 2007
In the second quarter of fiscal 2007, the Applied Biosystems group recorded a $4.8 million pre-tax
benefit related to the settlement of a patent infringement claim and a $3.0 million pre-tax benefit
related to our collection from a third party of a portion of its liability relative to our
settlement of a prior legal dispute. Additionally in the second quarter of fiscal 2007, the Celera
group recorded a $2.4 million pre-tax benefit related to the settlement of a litigation matter
associated with the former Online/Information Business, an information products and service
business.
In the first quarter of fiscal 2007, the Applied Biosystems group recorded a $9.1 million pre-tax
charge related to a settlement agreement entered into with another company which resolved
outstanding legal disputes with that company.
Fiscal 2006
In the first quarter of fiscal 2006, we recorded a $23.5 million pre-tax charge related to a
litigation matter and an award in an arbitration proceeding with Amersham Biosciences, now GE
Healthcare. We recorded the pre-tax charge as follows: $22.8 million at the Applied Biosystems
group and $0.7 million at the Celera group. The arbitrator awarded Amersham past damages based on
an increase in royalty rates for some of its DNA sequencing enzymes and kits that contain those
enzymes, plus interest, fees, and other costs. As a result of this decision, the Applied
Biosystems group recorded a pre-tax charge of $20.4 million in the first quarter of fiscal 2006,
$19.5 million of which was recorded in asset dispositions and legal settlements. In the second
quarter of fiscal 2006, we recorded an additional pre-tax charge of $3.1 million at the Applied
Biosystems group as a result of the final determination of interest related to the arbitration
award. We paid all amounts related to the arbitration matter in January 2006.
Acquired research and development
In the first quarter of fiscal 2007, the Applied Biosystems group recorded a $114.3 million charge
to write-off the value of acquired in-process research and development (IPR&D) in connection with
the acquisition of Agencourt Personal Genomics, Inc. (APG). As of the acquisition date, the
technological feasibility of the acquired project had not been established, and it was determined
that the acquired project had no future alternative use. The determination of the amount
attributed to acquired IPR&D took into consideration an independent appraisal performed by an
outside consultant. See Note 3 for more information on this acquisition.
Investments
In the first quarter of fiscal 2006, the Celera group recorded a pre-tax gain of $4.5 million in
the condensed consolidated statements of operations in gain on investments, net from the sale of a
non-strategic minority equity investment.
Tax items
Fiscal 2007
In December 2006, the President of the U.S. signed the Tax Relief and Health Care Act of 2006,
which extended the R&D tax credit from January 1, 2006 through December 31, 2007. The Celera group
included the estimated benefit of the current year R&D tax credit in the second quarter of fiscal
2007 estimated annual effective tax rate. In addition, the Celera group recorded a tax benefit of
$1.0 million in the second quarter of fiscal 2007 related to the R&D tax credit generated between
January 1, 2006 to June 30, 2006. In the first quarter of fiscal 2007, the Applied Biosystems
group recorded a tax benefit of $8.8 million related to a reduction in the valuation allowance for
some German net operating loss carryforwards.
Fiscal 2006
In the first quarter of fiscal 2006, the Applied Biosystems group recorded a tax benefit of $13.5
million related to the resolution of transfer pricing matters in Japan. During the second quarter
of fiscal 2006, the Applied Biosystems group recorded tax charges of $28.0 million related to
repatriation of cash balances held outside the U.S.
Note 3 Acquisition
In July 2006, we acquired APG for approximately $121 million in cash, including transaction costs.
At the time of the purchase, APG was a privately-held developer of next-generation genetic analysis
technology. APGs proprietary technology was based on stepwise ligation, a novel and very high
throughput approach to DNA analysis.
8
APPLERA CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
continued
In accordance with SFAS No. 141, Business Combinations, we accounted for this transaction as a
purchase of assets rather than a business combination since APG did not meet the definition of a
business as defined by Emerging Issues Task Force (EITF) Abstracts Issue 98-3, Determining
Whether a Nonmonetary Transaction Involves Receipt of Productive Assets or of a Business. The key
considerations impacting our accounting determination were that APG was primarily focused on
research and development activities, had not commenced principal operations, and did not have
products, customers or revenues. We allocated the purchase price as follows:
|
|
|
|
|
(Dollar amounts in millions) |
|
Fair Value |
|
|
Property, plant and equipment |
|
$ |
1.4 |
|
|
|
|
|
|
Intangible asset workforce |
|
|
1.5 |
|
Acquired IPR&D |
|
|
114.3 |
|
|
|
|
|
|
Deferred tax asset |
|
|
4.7 |
|
Deferred tax liability |
|
|
(0.5 |
) |
|
Total purchase price |
|
$ |
121.4 |
|
|
We allocated this transaction to the Applied Biosystems group. The estimated fair value
attributed to the workforce was determined based on the estimated cost to recruit, hire, and train
a workforce comparable to that in existence at APG at the time of our purchase of its assets. At
the time of the acquisition, approximately 20 employees of APG became employees of the Applied
Biosystems group. The recorded fair value of the workforce intangible asset is being amortized
over its expected period of benefit of 3 years.
At the time of the acquisition, APG was in the process of prosecuting certain patents, but none had
been issued. Any licenses APG had were not exclusive and did not provide it a measurable
technological advantage. As a result, neither the patents or licenses were deemed to be
identifiable assets and no value was assigned.
As of the acquisition date, the technological feasibility of the acquired IPR&D project had not
been established, and it was determined that the project had no future alternative use. The amount
attributed to acquired IPR&D took into consideration an independent appraisal performed by an
outside consultant and was developed using an income approach. The project was valued using a
discounted cash flow model and a discount rate of 30%. This discount rate was based on an
estimated weighted average cost of capital given APGs stage and development lifecycle. The
projected cash flows from the project were based on an estimate of future revenues and expenses
attributable to the project. The valuation assumptions were made solely for the purpose of
calculating projected cash flows and valuing the intangible assets acquired at the date of
acquisition. Additionally, the amount of purchase price which was in excess of the identifiable
assets was allocated to IPR&D, as goodwill could not result from an acquisition of assets. Actual
results may vary from the projected results.
The following table briefly describes the APG IPR&D project.
|
|
|
|
|
|
|
|
|
|
|
|
|
|
At Acquisition Date |
(Dollar amounts in millions) |
|
Fair Value |
|
|
Estimated Costs to Complete |
|
|
Approximate Percentage Completed |
|
Instruments |
|
$ |
66.6 |
|
|
$ |
10.0 |
|
|
35% |
|
|
|
|
|
|
|
|
|
|
|
Reagents |
|
|
47.7 |
|
|
|
6.0 |
|
|
25% |
|
|
|
|
|
|
|
|
|
|
|
|
Total |
|
$ |
114.3 |
|
|
$ |
16.0 |
|
|
|
|
The
instruments and reagents being developed are intended for very high throughput genetic
analysis applications, including DNA sequencing and expression profiling. The
initial instrument and reagents are expected to begin
9
APPLERA CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
continued
generating revenue in fiscal 2008. Enhanced
platforms are expected to begin generating revenues in fiscal 2010 and fiscal 2013.
Note 4 Earnings (Loss) per Share
The following table presents a reconciliation of basic and diluted earnings (loss) per share for
the three months ended December 31:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Applied Biosystems Group |
|
|
Celera Group |
(Dollar amounts in millions, except per share amounts) |
|
2006 |
|
|
2005 |
|
|
2006 |
|
|
2005 |
|
|
Net income (loss) |
|
$ |
74.8 |
|
|
$ |
30.9 |
|
|
$ |
(0.5 |
) |
|
$ |
(17.3 |
) |
Allocated intercompany sale of assets |
|
|
(0.1 |
) |
|
|
|
|
|
|
|
|
|
|
|
|
Allocated interperiod taxes |
|
|
0.3 |
|
|
|
0.5 |
|
|
|
|
|
|
|
|
|
|
Total net income (loss) allocated |
|
|
75.0 |
|
|
|
31.4 |
|
|
|
(0.5 |
) |
|
|
(17.3 |
) |
Less dividends declared on common stock |
|
|
7.8 |
|
|
|
7.8 |
|
|
|
|
|
|
|
|
|
|
Undistributed earnings (loss) |
|
$ |
67.2 |
|
|
$ |
23.6 |
|
|
$ |
(0.5 |
) |
|
$ |
(17.3 |
) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Allocation of basic earnings (loss) per share |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Basic distributed earnings per share(1) |
|
$ |
0.04 |
|
|
$ |
0.04 |
|
|
$ |
|
|
|
$ |
|
|
Basic undistributed earnings (loss) per share |
|
|
0.37 |
|
|
|
0.13 |
|
|
|
(0.01 |
) |
|
|
(0.23 |
) |
|
Total basic earnings (loss) per share |
|
$ |
0.41 |
|
|
$ |
0.17 |
|
|
$ |
(0.01 |
) |
|
$ |
(0.23 |
) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Allocation of diluted earnings (loss) per share |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Diluted distributed earnings per share(1) |
|
$ |
0.04 |
|
|
$ |
0.04 |
|
|
$ |
|
|
|
$ |
|
|
Diluted undistributed earnings (loss) per share |
|
|
0.35 |
|
|
|
0.13 |
|
|
|
(0.01 |
) |
|
|
(0.23 |
) |
|
Total diluted earnings (loss) per share |
|
$ |
0.39 |
|
|
$ |
0.17 |
|
|
$ |
(0.01 |
) |
|
$ |
(0.23 |
) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Weighted average number of common shares |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Basic |
|
|
183.5 |
|
|
|
185.9 |
|
|
|
78.2 |
|
|
|
74.8 |
|
Common stock equivalents |
|
|
7.9 |
|
|
|
4.3 |
|
|
|
|
|
|
|
|
|
|
Diluted |
|
|
191.4 |
|
|
|
190.2 |
|
|
|
78.2 |
|
|
|
74.8 |
|
|
|
|
|
(1) Amounts represent actual dividends per share distributed. |
10
APPLERA CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
continued
The following table presents a reconciliation of basic and diluted earnings (loss) per share for
the six months ended December 31:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Applied Biosystems Group |
|
|
Celera Group |
(Dollar amounts in millions, except per share amounts) |
|
2006 |
|
|
2005 |
|
|
2006 |
|
|
2005 |
|
|
Net income (loss) |
|
$ |
16.1 |
|
|
$ |
74.0 |
|
|
$ |
(7.5 |
) |
|
$ |
(34.1 |
) |
Allocated intercompany sale of assets |
|
|
(0.2 |
) |
|
|
|
|
|
|
|
|
|
|
|
|
Allocated interperiod taxes |
|
|
0.1 |
|
|
|
(0.7 |
) |
|
|
|
|
|
|
|
|
|
Total net income (loss) allocated |
|
|
16.0 |
|
|
|
73.3 |
|
|
|
(7.5 |
) |
|
|
(34.1 |
) |
Less dividends declared on common stock |
|
|
15.6 |
|
|
|
16.1 |
|
|
|
|
|
|
|
|
|
|
Undistributed earnings (loss) |
|
$ |
0.4 |
|
|
$ |
57.2 |
|
|
$ |
(7.5 |
) |
|
$ |
(34.1 |
) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Allocation of basic earnings (loss) per share |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Basic distributed earnings per share(1) |
|
$ |
0.09 |
|
|
$ |
0.09 |
|
|
$ |
|
|
|
$ |
|
|
Basic undistributed earnings (loss) per share |
|
|
|
|
|
|
0.29 |
|
|
|
(0.10 |
) |
|
|
(0.46 |
) |
|
Total basic earnings (loss) per share |
|
$ |
0.09 |
|
|
$ |
0.38 |
|
|
$ |
(0.10 |
) |
|
$ |
(0.46 |
) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Allocation of diluted earnings (loss) per share |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Diluted distributed earnings per share(1) |
|
$ |
0.08 |
|
|
$ |
0.09 |
|
|
$ |
|
|
|
$ |
|
|
Diluted undistributed earnings (loss) per share |
|
|
|
|
|
|
0.29 |
|
|
|
(0.10 |
) |
|
|
(0.46 |
) |
|
Total diluted earnings (loss) per share |
|
$ |
0.08 |
|
|
$ |
0.38 |
|
|
$ |
(0.10 |
) |
|
$ |
(0.46 |
) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Weighted average number of common shares |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Basic |
|
|
182.8 |
|
|
|
190.7 |
|
|
|
78.0 |
|
|
|
74.6 |
|
Common stock equivalents |
|
|
7.5 |
|
|
|
3.5 |
|
|
|
|
|
|
|
|
|
|
Diluted |
|
|
190.3 |
|
|
|
194.2 |
|
|
|
78.0 |
|
|
|
74.6 |
|
|
|
|
|
(1) Amounts represent actual dividends per share distributed. |
Options to purchase shares at exercise prices greater than the average market prices were excluded
from the computation of diluted earnings per share because the effect was antidilutive.
Additionally, options to purchase shares of Applera Corporation-Celera Group Common Stock
(Applera-Celera stock) were excluded from the computation of diluted loss per share because the
effect was antidilutive. The following table presents the number of shares excluded from the
diluted earnings and loss per share computations at December 31:
|
|
|
|
|
|
|
|
|
(Shares in millions) |
|
2006 |
|
|
2005 |
|
|
Applera-Applied Biosystems stock |
|
|
4.4 |
|
|
|
11.6 |
|
Applera-Celera stock |
|
|
7.0 |
|
|
|
11.0 |
|
|
11
APPLERA CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
continued
Note 5 Comprehensive Gain
The components of comprehensive gain (loss) are reflected net of tax, except for foreign currency
translation adjustments, which are generally not adjusted for income taxes as they relate to
indefinite investments in nonU.S. subsidiaries. Comprehensive gain was as follows:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Three months ended |
|
|
Six months ended |
|
|
|
December 31, |
|
|
December 31, |
|
(Dollar amounts in millions) |
|
2006 |
|
|
2005 |
|
|
2006 |
|
|
2005 |
|
|
Net income |
|
$ |
74.5 |
|
|
$ |
14.1 |
|
|
$ |
8.5 |
|
|
$ |
39.3 |
|
Other comprehensive gain (loss): |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Net unrealized gains (losses) on investments |
|
|
1.1 |
|
|
|
0.4 |
|
|
|
3.2 |
|
|
|
(0.1 |
) |
Net unrealized gains on investments reclassified into earnings |
|
|
(0.1 |
) |
|
|
|
|
|
|
(0.3 |
) |
|
|
|
|
Net unrealized gains (losses) on hedge contracts |
|
|
(1.5 |
) |
|
|
5.4 |
|
|
|
0.5 |
|
|
|
7.0 |
|
Net unrealized (gains) losses on hedge contracts reclassified
into earnings |
|
|
0.5 |
|
|
|
(3.1 |
) |
|
|
0.5 |
|
|
|
(1.0 |
) |
Foreign currency translation adjustments |
|
|
3.9 |
|
|
|
(11.2 |
) |
|
|
6.4 |
|
|
|
(14.5 |
) |
|
Total other comprehensive gain (loss) |
|
|
3.9 |
|
|
|
(8.5 |
) |
|
|
10.3 |
|
|
|
(8.6 |
) |
|
Total comprehensive gain |
|
$ |
78.4 |
|
|
$ |
5.6 |
|
|
$ |
18.8 |
|
|
$ |
30.7 |
|
|
Note 6 Inventories
Inventories included the following components:
|
|
|
|
|
|
|
|
|
|
|
December 31, |
|
|
June 30, |
|
(Dollar amounts in millions) |
|
2006 |
|
|
2006 |
|
|
Raw materials and supplies |
|
$ |
57.3 |
|
|
$ |
44.3 |
|
Work-in-process |
|
|
7.3 |
|
|
|
12.8 |
|
Finished products |
|
|
86.8 |
|
|
|
80.6 |
|
|
Total inventories, net |
|
$ |
151.4 |
|
|
$ |
137.7 |
|
|
Note 7 Assets Held for Sale
In connection with the Celera groups decision to exit its small molecule drug discovery and
development programs during the third quarter of fiscal 2006, the Celera group decided to pursue
the sale of its South San Francisco, California facility. See Note 8 to our consolidated financial
statements included in our 2006 Annual Report to Stockholders. As a result of this decision, we
reclassified $11.5 million of property, plant and equipment into assets held for sale in the third
quarter of fiscal 2006 and recorded a $5.8 million pre-tax charge that represented the write-down
of the carrying amount of this facility to its then current estimated market value less estimated
selling costs. As discussed in Note 2, the Celera group recorded an additional $3.0 million
pre-tax impairment charge for this facility during the second quarter of fiscal 2007. The sale of
this facility is expected to occur by December 31, 2007.
12
APPLERA CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
continued
Note 8 Goodwill and Intangible Assets
The carrying amounts of our intangible assets were as follows:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
December 31, 2006 |
|
|
June 30, 2006 |
|
|
|
Gross |
|
|
|
|
|
|
Gross |
|
|
|
|
|
|
Carrying |
|
|
Accumulated |
|
|
Carrying |
|
|
Accumulated |
|
(Dollar amounts in millions) |
|
Amount |
|
|
Amortization |
|
|
Amount |
|
|
Amortization |
|
|
Amortized intangible assets |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Acquired technology |
|
$ |
83.5 |
|
|
$ |
51.3 |
|
|
$ |
83.3 |
|
|
$ |
44.5 |
|
Patents |
|
|
29.9 |
|
|
|
24.1 |
|
|
|
29.9 |
|
|
|
22.9 |
|
Customer relationships |
|
|
27.1 |
|
|
|
3.2 |
|
|
|
27.1 |
|
|
|
1.6 |
|
Other |
|
|
1.8 |
|
|
|
0.4 |
|
|
|
0.3 |
|
|
|
0.3 |
|
|
Total amortized intangible assets |
|
$ |
142.3 |
|
|
$ |
79.0 |
|
|
$ |
140.6 |
|
|
$ |
69.3 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Unamortized intangible assets |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Trade name |
|
|
4.9 |
|
|
|
|
|
|
|
4.9 |
|
|
|
|
|
|
Total |
|
$ |
147.2 |
|
|
$ |
79.0 |
|
|
$ |
145.5 |
|
|
$ |
69.3 |
|
|
Aggregate amortization expense was as follows:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Three months ended |
|
|
Six months ended |
|
|
|
December 31, |
|
|
December 31, |
|
(Dollar amounts in millions) |
|
2006 |
|
|
2005 |
|
|
2006 |
|
|
2005 |
|
|
Applied Biosystems group |
|
$ |
4.5 |
|
|
$ |
1.7 |
|
|
$ |
8.9 |
|
|
$ |
3.5 |
|
Celera group |
|
|
0.6 |
|
|
|
1.0 |
|
|
|
1.2 |
|
|
|
2.2 |
|
|
Consolidated |
|
$ |
5.1 |
|
|
$ |
2.7 |
|
|
$ |
10.1 |
|
|
$ |
5.7 |
|
|
We record amortization expense in cost of sales. However, amortization of acquisition-related
intangible assets is recorded in the amortization of purchased intangible assets in the condensed
consolidated statements of operations. At December 31, 2006, we estimated annual amortization
expense of our intangible assets for each of the next five fiscal years as shown in the following
table. Future acquisitions or impairment events could cause these amounts to change.
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Applied |
|
|
|
|
|
|
|
|
|
Biosystems |
|
|
Celera |
|
|
|
|
(Dollar amounts in millions) |
|
Group |
|
|
Group |
|
|
Consolidated |
|
|
Remainder of fiscal 2007 |
|
$ |
8.4 |
|
|
$ |
1.0 |
|
|
$ |
9.4 |
|
2008 |
|
|
14.4 |
|
|
|
0.6 |
|
|
|
15.0 |
|
2009 |
|
|
13.1 |
|
|
|
0.2 |
|
|
|
13.3 |
|
2010 |
|
|
10.4 |
|
|
|
0.2 |
|
|
|
10.6 |
|
2011 |
|
|
6.6 |
|
|
|
0.2 |
|
|
|
6.8 |
|
|
The carrying amount of goodwill at December 31, 2006 and June 30, 2006, was $245.9 million, of
which $243.2 million was allocated to the Applied Biosystems group and $2.7 million was allocated
to the Celera group.
13
APPLERA CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
continued
Note 9 Supplemental Cash Flow Information
Significant non-cash financing activity for the six months ended December 31 was as follows:
|
|
|
|
|
|
|
|
|
(Dollar amounts in millions) |
|
2006 |
|
|
2005 |
|
|
Dividends declared but not paid |
|
$ |
7.8 |
|
|
$ |
7.9 |
|
Tax benefit related to employee stock options |
|
|
14.0 |
|
|
|
5.1 |
|
|
Note 10 Guarantees
Leases
We provide lease-financing options to our customers through third party financing companies. For
some leases, the financing companies have recourse to us for any unpaid principal balance on
default by the customer. The leases typically have terms of two to three years and are secured by
the underlying instrument. In the event of default by a customer, we would repossess the
underlying instrument. We record revenues from these transactions on the completion of
installation and acceptance of products and maintain a reserve for estimated losses on all lease
transactions with recourse provisions based on historical default rates and current economic
conditions. At December 31, 2006, the financing companies outstanding balance of lease
receivables with recourse to us was $6.3 million. We believe that we could recover the entire
balance from the resale of the underlying instruments in the event of default by all customers.
Pension Benefits
As part of the divestiture of our Analytical Instruments business in fiscal 1999, the purchaser of
the Analytical Instruments business is paying for the pension benefits for employees of a former
German subsidiary. However, we guaranteed payment of these pension benefits should the purchaser
fail to do so, as these payment obligations were not transferable to the buyer under German law.
The guaranteed payment obligation, which approximated $58 million at December 31, 2006, is not
expected to have a material adverse effect on our condensed consolidated statement of financial
position.
Indemnifications
In the normal course of business, we enter into some agreements under which we indemnify third
parties for intellectual property infringement claims or claims arising from breaches of
representations or warranties. In addition, from time to time, we provide indemnity protection to
third parties for claims relating to past performance arising from undisclosed liabilities, product
liabilities, environmental obligations, representations and warranties, and other claims. In these
agreements, the scope and amount of remedy, or the period in which claims can be made, may be
limited. It is not possible to determine the maximum potential amount of future payments, if any,
due under these indemnities due to the conditional nature of the obligations and the unique facts
and circumstances involved in each agreement. Historically, payments made related to these
indemnifications have not been material to our consolidated financial position.
Product Warranties
We accrue warranty costs for product sales at the time of shipment based on historical experience
as well as anticipated product performance. Our product warranties extend over a specified period
of time ranging up to two years from the date of sale depending on the product subject to warranty.
The product warranty accrual covers parts and labor for repairs and replacements covered by our
product warranties. We periodically review the adequacy of our warranty reserve, and adjust, if
necessary, the warranty percentage and accrual based on actual experience and estimated costs to be
incurred.
14
APPLERA CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
continued
The following table provides an analysis of the warranty reserve for the six months ended December
31:
|
|
|
|
|
|
|
|
|
(Dollar amounts in millions) |
|
2006 |
|
|
2005 |
|
|
Balance beginning of period |
|
$ |
10.6 |
|
|
$ |
14.0 |
|
Accruals for warranties |
|
|
8.0 |
|
|
|
9.2 |
|
Usage of reserve |
|
|
(8.2 |
) |
|
|
(10.4 |
) |
|
Balance at December 31 |
|
$ |
10.4 |
|
|
$ |
12.8 |
|
|
Note 11 Pension and Other Postretirement Benefits
The components of net pension and postretirement benefit expenses for the three and six month
periods ended December 31 were as follows:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Three months ended |
|
|
Six months ended |
|
|
|
December 31, |
|
|
December 31, |
|
(Dollar amounts in millions) |
|
2006 |
|
|
2005 |
|
|
2006 |
|
|
2005 |
|
|
Pension |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Service cost |
|
$ |
0.8 |
|
|
$ |
0.7 |
|
|
$ |
1.8 |
|
|
$ |
1.3 |
|
Interest cost |
|
|
10.9 |
|
|
|
8.9 |
|
|
|
21.8 |
|
|
|
18.0 |
|
Expected return on plan assets |
|
|
(11.7 |
) |
|
|
(9.6 |
) |
|
|
(23.3 |
) |
|
|
(19.1 |
) |
Amortization of prior service cost |
|
|
0.2 |
|
|
|
(0.1 |
) |
|
|
0.4 |
|
|
|
(0.1 |
) |
Amortization of losses |
|
|
1.4 |
|
|
|
2.0 |
|
|
|
2.6 |
|
|
|
3.9 |
|
|
Net periodic expense |
|
$ |
1.6 |
|
|
$ |
1.9 |
|
|
$ |
3.3 |
|
|
$ |
4.0 |
|
|
Postretirement Benefit |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Service cost |
|
$ |
|
|
|
$ |
0.1 |
|
|
$ |
0.1 |
|
|
$ |
0.1 |
|
Interest cost |
|
|
0.9 |
|
|
|
0.8 |
|
|
|
1.8 |
|
|
|
1.6 |
|
Amortization of (gains) losses |
|
|
(0.1 |
) |
|
|
|
|
|
|
(0.2 |
) |
|
|
0.1 |
|
|
Net periodic expense |
|
$ |
0.8 |
|
|
$ |
0.9 |
|
|
$ |
1.7 |
|
|
$ |
1.8 |
|
|
We contributed approximately $1 million to our foreign and non-qualified domestic plans during
the six months ended December 31, 2006, and expect to contribute an additional $1 million during
the remainder of fiscal 2007. Based on the level of our contributions to the qualified U.S.
pension plan during fiscal 2006 and previous years, combined with the performance of the assets
invested in the plan, we do not expect to have to fund our qualified U.S. pension plan in fiscal
2007 in order to meet minimum statutory funding requirements. We made benefit payments of
approximately $4 million under the postretirement plan during the six months ended December 31,
2006, and we expect to make approximately $3 million of additional benefit payments during the
remainder of fiscal 2007.
Note 12 Contingencies
Supply Arrangement
Delphi Medical Systems Texas Corporation (Delphi Medical Systems) is a supplier of some
instruments, parts, and components to the Applied Biosystems group under a manufacturing and supply
contract. On October 8, 2005, Delphi Medical Systems and its parent Delphi Corporation filed a
petition in the United States Bankruptcy Court for the Southern District of New York seeking relief
under the provisions of Chapter 11 of the federal Bankruptcy Code. As a result of the bankruptcy
filing, the Applied Biosystems group had a pre-petition accounts receivable balance with Delphi
Medical Systems of approximately $7 million. However, under a recoupment order entered by the
Bankruptcy Court that became final on November 3, 2006, the Applied Biosystems group recouped this
remaining pre-petition accounts receivable balance by offsetting against this balance amounts owed
by the Applied Biosystems group to Delphi Medical Systems. Since the filing of the bankruptcy
petition, Delphi has continued to supply instruments, parts, and components to the Applied
Biosystems group under the contract, but it has informed the Applied Biosystems group that it does
not intend to continue performing under the manufacturing and supply agreement after approximately
May 2007. The Applied Biosystems group intends to use its own existing manufacturing facilities to
replace the supply of some critical
15
APPLERA CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
continued
items that it has been purchasing from Delphi Medical Systems
and is evaluating the use of new suppliers for other critical items. In anticipation of the
termination of supply from Delphi Medical Systems, the two companies recently entered into an
amendment to the manufacturing and supply agreement that provides for larger than normal purchases
of some products to increase inventory of critical items and the purchase of raw materials and
tooling to help facilitate the transition of the manufacture of some products to the Applied
Biosystems group.
Legal Proceedings
We are involved in various lawsuits, arbitrations, investigations, and other legal actions from
time to time with both private parties and governmental entities. These legal actions currently
involve, for example, commercial, intellectual property, antitrust, environmental, securities, and
employment matters. The following is a description of some claims we are currently defending,
including some counterclaims brought against us in response to claims filed by us against others.
We believe that we have meritorious defenses against the claims currently asserted against us,
including those described below, and intend to defend them vigorously.
The company and some of its officers are defendants in a lawsuit brought on behalf of purchasers of
Applera-Celera stock in our follow-on public offering of Applera-Celera stock completed on March 6,
2000. In the offering, we sold an aggregate of approximately 4.4 million shares of Applera-Celera
stock at a public offering price of $225 per share. The lawsuit, which was commenced with the
filing of several complaints in April and May 2000, is pending in the U.S. District Court for the
District of Connecticut, and an amended consolidated complaint was filed on August 21, 2001. The
consolidated complaint generally alleges that the prospectus used in connection with the offering
was inaccurate or misleading because it failed to adequately disclose the alleged opposition of the
Human Genome Project and two of its supporters, the governments of the U.S. and the U.K., to
providing patent protection to our genomic-based products. Although the Celera group has never
sought, or intended to seek, a patent on the basic human genome sequence data, the complaint also
alleges that we did not adequately disclose the risk that the Celera group would not be able to
patent this data. The consolidated complaint seeks monetary damages, rescission, costs and
expenses, and other relief as the court deems proper. On March 31, 2005, the court certified the
case as a class action.
We filed a patent infringement action against Bio-Rad Laboratories, Inc., MJ Research, Inc., and
Stratagene Corporation in the U.S. District Court for the District of Connecticut on November 9,
2004. The complaint alleges that the defendants infringe U.S. Patent No. 6,814,934. The complaint
specifically alleges that the defendants activities involving instruments for real-time PCR
detection result in infringement. We are seeking monetary damages, costs, expenses, injunctive
relief, and other relief as the court deems proper. Bio-Rad and MJ Research answered the complaint
and counterclaimed for declaratory relief that the 934 patent was invalid and not infringed, but
we settled all of these claims with Bio-Rad and MJ Research in February 2006. Stratagene also
answered the complaint and counterclaimed for declaratory relief that the 934 patent is invalid
and not infringed. Stratagene is seeking dismissal of our complaint, a judgment that the 934
patent is invalid and not infringed, costs and expenses, and other relief as the court deems
proper.
On-Line Technologies, Inc. (since acquired by MKS Instruments, Inc.) filed claims for patent
infringement, trade secret misappropriation, fraud, breach of contract and unfair trade practices
against PerkinElmer, Inc., Sick UPA, GmbH, and us in the U.S. District Court for the District of
Connecticut on or about November 3, 1999. The complaint alleged that products called the Spectrum
One and the MCS100E manufactured by former divisions of the Applied Biosystems group, which
divisions were sold to the co-defendants in this case, were based on allegedly proprietary
information belonging to On-Line Technologies and that the MCS100E infringed U.S. Patent No.
5,440,143. On-Line Technologies was seeking monetary damages, costs, expenses, injunctive relief,
and other relief. On April 2, 2003, the U.S. District Court for the District of Connecticut
granted our summary judgment motion and dismissed all claims brought by On-Line Technologies.
On-Line Technologies filed an appeal with the U.S. Court of Appeals for the Federal Circuit seeking
reinstatement of its claims, and on October 13, 2004, the Court of Appeals upheld dismissal of all
claims except for the patent infringement claim, which was to be decided by the District Court in
subsequent proceedings. However, the parties settled all of these claims under an agreement that
was effective January 18, 2007, and the District Court formally dismissed the case on January 26,
2007.
Enzo Biochem, Inc., Enzo Life Sciences, Inc., and Yale University filed a patent infringement
action against us in the U.S. District Court for the District of Connecticut on June 8, 2004. The
complaint alleges that we are infringing six
16
APPLERA CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
continued
patents. Four of these patents are assigned to Yale
University and licensed exclusively to Enzo Biochem, i.e., U.S. Patent No. 4,476,928, entitled
Modified Nucleotides and Polynucleotides and Complexes Formed Therefrom, U.S. Patent No.
5,449,767, entitled Modified Nucleotides and Polynucleotides and Methods of Preparing Same, U.S.
Patent No. 5,328,824 entitled Methods of Using Labeled Nucleotides, and U.S. Patent No.
4,711,955, entitled Modified Nucleotides and Polynucleotides and Methods of Preparing and Using
Same. The other two patents are assigned to Enzo Life Sciences, i.e., U.S. Patent No. 5,082,830
entitled End Labeled Nucleotide Probe and U.S. Patent No. 4,994,373 entitled Methods and
Structures Employing Compoundly Labeled Polynucleotide Probes. The allegedly infringing
products include the Applied Biosystems groups sequencing reagent kits, its TaqMan® genotyping and
gene expression assays, and the gene expression microarrays used with its Expression Array System.
Enzo Biochem, Enzo Life Sciences, and Yale University are seeking monetary damages, costs,
expenses, injunctive relief, and other relief as the court deems proper.
Molecular Diagnostics Laboratories filed a class action complaint against us and Hoffmann-La Roche,
Inc. in the U.S. District Court for the District of Columbia on September 23, 2004, and filed an
amended complaint on July 5, 2006. The amended complaint alleges anticompetitive conduct in
connection with the sale of Taq DNA polymerase. The anticompetitive conduct is alleged to arise
from the prosecution and enforcement of U.S. Patent No. 4,889,818. This patent is assigned to
Hoffmann-La Roche, with whom we have a commercial relationship covering, among other things, this
patent and the sale of Taq DNA polymerase. The complaint seeks monetary damages, costs, expenses,
injunctive relief, and other relief as the court deems proper. On July 5, 2006, the court
certified the case as a class action.
We are involved in several legal actions with Thermo Electron Corporation and its subsidiary Thermo
Finnigan LLC. These legal actions commenced when we, together with MDS, Inc. and our Applied
Biosystems/MDS Sciex Instruments joint venture with MDS, filed a patent infringement action against
Thermo Electron in the U.S. District Court for the District of Delaware on September 3, 2004. The
complaint alleges infringement by Thermo Electron of U.S. Patent No. 4,963,736, and seeks monetary
damages, costs, expenses, and other relief as the court deems proper. Thermo Electron has answered
the complaint and counterclaimed for declaratory relief that the 736 patent is invalid, not
infringed, and unenforceable, and is seeking dismissal of our complaint, a judgment that the 736
patent is invalid, not infringed, and unenforceable, costs and expenses, and other relief as the
court deems proper. After the filing of the action against Thermo Electron, on December 8, 2004,
Thermo Finnigan filed a patent infringement action against us in the U.S. District Court for the
District of Delaware. The complaint alleges that we have infringed U.S. Patent No. 5,385,654 as a
result of, for example, our Applied Biosystems groups commercialization of the ABI
PRISM® 3700 Genetic Analyzer. Thermo Finnigan is seeking monetary damages, costs,
expenses, and other relief as the court deems proper. We have answered the complaint and
counterclaimed for declaratory relief that the 654 patent is invalid, not infringed, and
unenforceable, and are seeking dismissal of Thermo Finnigans complaint, a judgment that the 654
patent is invalid, not infringed, and unenforceable, costs and expenses, and other relief as the
court deems proper. Thermo Finnigan subsequently filed a second patent infringement action against
us, MDS, and the Applied Biosystems/MDS Sciex Instruments joint venture, in the U.S. District Court
for the District of Delaware on February 23, 2005. The complaint alleges that we and the other
defendants have infringed U.S. Patent No. 6,528,784 as a result of, for example, our
commercialization of the API 5000 LC/MS/MS system. Thermo Finnigan is seeking monetary damages,
costs, expenses, and other relief as the court deems proper. We have answered the complaint and
counterclaimed for declaratory relief that the 784 patent is invalid and not infringed, and are
seeking dismissal of Thermo Finnigans complaint, a judgment that the 784 patent is invalid and
not infringed, costs and expenses, and other relief as the court deems proper.
Other than for items deemed not material, we have not accrued for any potential losses in the legal
proceedings described above because we believe that an adverse determination is not probable, and
potential losses cannot be reasonably estimated, in any of these proceedings. However, the outcome
of legal actions is inherently uncertain, and we cannot be sure that we will prevail in any of the
proceedings described above or in our other legal actions. An adverse determination in some of our
current legal actions, particularly the proceedings described above, could have a material adverse
effect on us and our consolidated financial statements.
17
APPLERA CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
continued
Note 13 Segment and Consolidating Information
Presented below is our segment and consolidating financial information, including the allocation of
expenses between our segments in accordance with our allocation policies, as well as other related
party transactions, such as sales of products between segments. Our board of directors approves
the method of allocating earnings to each class of common stock for purposes of calculating
earnings per share. This determination is generally based on net income or loss amounts of the
corresponding group calculated in accordance with GAAP, consistently applied.
As a result of the restructuring effective January 1, 2006 and the manner by which our management
now operates and assesses our businesses, Celera Diagnostics is no longer a separate segment within
Applera and we have restated prior period condensed consolidating financial information to reflect
this change. See Note 16 to our consolidated financial statements included in our 2006 Annual
Report to Stockholders for a detailed description of the segments and the management and allocation
policies applicable to the attribution of assets, liabilities, revenues and expenses to the
segments (which information is incorporated in this quarterly report by reference).
The following table summarizes revenues earned between segments:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Three months ended |
|
|
Six months ended |
|
|
|
December 31, |
|
|
December 31, |
|
(Dollar amounts in millions) |
|
2006 |
|
|
2005 |
|
|
2006 |
|
|
2005 |
|
|
Applied Biosystems Group |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Sales to the Celera group (a) |
|
$ |
1.3 |
|
|
$ |
1.4 |
|
|
$ |
2.4 |
|
|
$ |
2.9 |
|
|
Celera Group |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Royalties from the Applied Biosystems group (b) |
|
$ |
|
|
|
$ |
1.1 |
|
|
$ |
|
|
|
$ |
2.0 |
|
|
|
|
|
(a) |
|
The Applied Biosystems group recorded net revenues from leased instruments and
sales of consumables and project materials to the Celera group. |
|
(b) |
|
The Celera group recorded net revenues primarily for royalties generated from sales
by the Applied Biosystems group of products integrating the Celera Discovery System TM
and some other genomic and biological information under a marketing and distribution agreement.
The Celera group forgave future royalties related to this agreement as discussed in Note 15 to our
consolidated financial statements included in our 2006 Annual Report to Stockholders. |
Additionally, the Applied Biosystems group received, without reimbursement, $13.3 million in the
first six months of fiscal 2007 and $19.1 million in the first six months of fiscal 2006 of tax
benefits generated by the Celera group in accordance with our tax allocation policy.
In the following consolidating financial information, the Eliminations column represents the
elimination of intersegment activity.
18
APPLERA CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
continued
Condensed Consolidating Statement of Operations for the Three Months Ended December 31, 2006
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Applied |
|
|
|
|
|
|
|
|
|
|
|
|
Biosystems |
|
|
Celera |
|
|
|
|
|
|
|
(Dollar amounts in thousands) |
|
Group |
|
|
Group |
|
|
Eliminations |
|
Consolidated |
|
|
Products |
|
$ |
440,088 |
|
|
$ |
2,758 |
|
|
$ |
|
|
|
$ |
442,846 |
|
Services |
|
|
60,782 |
|
|
|
|
|
|
|
|
|
|
|
60,782 |
|
Other |
|
|
27,761 |
|
|
|
10,460 |
|
|
|
|
|
|
|
38,221 |
|
|
Net revenues from external customers |
|
|
528,631 |
|
|
|
13,218 |
|
|
|
|
|
|
|
541,849 |
|
Intersegment revenues |
|
|
1,349 |
|
|
|
|
|
|
|
(1,349 |
) |
|
|
|
|
|
Total Net Revenues |
|
|
529,980 |
|
|
|
13,218 |
|
|
|
(1,349 |
) |
|
|
541,849 |
|
|
Products |
|
|
205,905 |
|
|
|
4,397 |
|
|
|
(500 |
) |
|
|
209,802 |
|
Services |
|
|
26,622 |
|
|
|
|
|
|
|
(83 |
) |
|
|
26,539 |
|
Other |
|
|
2,956 |
|
|
|
99 |
|
|
|
|
|
|
|
3,055 |
|
|
Cost of Sales |
|
|
235,483 |
|
|
|
4,496 |
|
|
|
(583 |
) |
|
|
239,396 |
|
|
Gross Margin |
|
|
294,497 |
|
|
|
8,722 |
|
|
|
(766 |
) |
|
|
302,453 |
|
Selling, general and administrative |
|
|
134,229 |
|
|
|
5,557 |
|
|
|
15,056 |
|
|
|
154,842 |
|
Corporate allocated expenses |
|
|
13,295 |
|
|
|
1,768 |
|
|
|
(15,063 |
) |
|
|
|
|
Research, development and engineering |
|
|
50,876 |
|
|
|
11,935 |
|
|
|
(651 |
) |
|
|
62,160 |
|
Amortization of purchased intangible assets |
|
|
2,842 |
|
|
|
|
|
|
|
|
|
|
|
2,842 |
|
Employee-related charges, asset
impairments and other |
|
|
|
|
|
|
2,513 |
|
|
|
|
|
|
|
2,513 |
|
Asset dispositions and legal settlements |
|
|
(7,788 |
) |
|
|
(2,357 |
) |
|
|
|
|
|
|
(10,145 |
) |
|
Operating Income (Loss) |
|
|
101,043 |
|
|
|
(10,694 |
) |
|
|
(108 |
) |
|
|
90,241 |
|
Interest income, net |
|
|
3,391 |
|
|
|
6,954 |
|
|
|
|
|
|
|
10,345 |
|
Other income (expense), net |
|
|
927 |
|
|
|
112 |
|
|
|
|
|
|
|
1,039 |
|
|
Income (Loss) before Income Taxes |
|
|
105,361 |
|
|
|
(3,628 |
) |
|
|
(108 |
) |
|
|
101,625 |
|
Provision (benefit) for income taxes |
|
|
30,579 |
|
|
|
(3,142 |
) |
|
|
(301 |
) |
|
|
27,136 |
|
|
Net Income (Loss) |
|
$ |
74,782 |
|
|
$ |
(486 |
) |
|
$ |
193 |
|
|
$ |
74,489 |
|
|
19
APPLERA CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
continued
Condensed Consolidating Statement of Operations for the Six Months Ended December 31, 2006
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Applied |
|
|
|
|
|
|
|
|
|
|
|
|
Biosystems |
|
|
Celera |
|
|
|
|
|
|
|
(Dollar amounts in thousands) |
|
Group |
|
|
Group |
|
|
Eliminations |
|
|
Consolidated |
|
|
Products |
|
$ |
828,684 |
|
|
$ |
5,244 |
|
|
$ |
|
|
|
$ |
833,928 |
|
Services |
|
|
118,922 |
|
|
|
|
|
|
|
|
|
|
|
118,922 |
|
Other |
|
|
56,205 |
|
|
|
18,203 |
|
|
|
|
|
|
|
74,408 |
|
|
Net revenues from external customers |
|
|
1,003,811 |
|
|
|
23,447 |
|
|
|
|
|
|
|
1,027,258 |
|
Intersegment revenues |
|
|
2,442 |
|
|
|
|
|
|
|
(2,442 |
) |
|
|
|
|
|
Total Net Revenues |
|
|
1,006,253 |
|
|
|
23,447 |
|
|
|
(2,442 |
) |
|
|
1,027,258 |
|
|
Products |
|
|
399,281 |
|
|
|
8,041 |
|
|
|
(861 |
) |
|
|
406,461 |
|
Services |
|
|
51,291 |
|
|
|
|
|
|
|
(154 |
) |
|
|
51,137 |
|
Other |
|
|
5,626 |
|
|
|
256 |
|
|
|
|
|
|
|
5,882 |
|
|
Cost of Sales |
|
|
456,198 |
|
|
|
8,297 |
|
|
|
(1,015 |
) |
|
|
463,480 |
|
|
Gross Margin |
|
|
550,055 |
|
|
|
15,150 |
|
|
|
(1,427 |
) |
|
|
563,778 |
|
Selling, general and administrative |
|
|
257,774 |
|
|
|
11,204 |
|
|
|
28,249 |
|
|
|
297,227 |
|
Corporate allocated expenses |
|
|
24,900 |
|
|
|
3,362 |
|
|
|
(28,262 |
) |
|
|
|
|
Research, development and engineering |
|
|
95,991 |
|
|
|
25,156 |
|
|
|
(1,085 |
) |
|
|
120,062 |
|
Amortization of purchased intangible assets |
|
|
5,579 |
|
|
|
|
|
|
|
|
|
|
|
5,579 |
|
Employee-related charges, asset
impairments, and other |
|
|
|
|
|
|
6,013 |
|
|
|
|
|
|
|
6,013 |
|
Asset dispositions and legal settlements |
|
|
1,299 |
|
|
|
(2,357 |
) |
|
|
|
|
|
|
(1,058 |
) |
Acquired research and development |
|
|
114,251 |
|
|
|
|
|
|
|
|
|
|
|
114,251 |
|
|
Operating Income (Loss) |
|
|
50,261 |
|
|
|
(28,228 |
) |
|
|
(329 |
) |
|
|
21,704 |
|
Gain on investments, net |
|
|
209 |
|
|
|
|
|
|
|
|
|
|
|
209 |
|
Interest income, net |
|
|
6,021 |
|
|
|
13,537 |
|
|
|
|
|
|
|
19,558 |
|
Other income (expense), net |
|
|
2,241 |
|
|
|
215 |
|
|
|
|
|
|
|
2,456 |
|
|
Income (Loss) before Income Taxes |
|
|
58,732 |
|
|
|
(14,476 |
) |
|
|
(329 |
) |
|
|
43,927 |
|
Provision (benefit) for income taxes |
|
|
42,672 |
|
|
|
(6,939 |
) |
|
|
(283 |
) |
|
|
35,450 |
|
|
Net Income (Loss) |
|
$ |
16,060 |
|
|
$ |
(7,537 |
) |
|
$ |
(46 |
) |
|
$ |
8,477 |
|
|
20
APPLERA CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
continued
Condensed Consolidating Statement of Financial Position at December 31, 2006
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Applied |
|
|
|
|
|
|
|
|
|
|
|
|
Biosystems |
|
|
Celera |
|
|
|
|
|
|
|
(Dollar amounts in thousands) |
|
Group |
|
|
Group |
|
|
Eliminations |
|
|
Consolidated |
|
|
Assets |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Current assets |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Cash and cash equivalents |
|
$ |
296,514 |
|
|
$ |
22,831 |
|
|
$ |
|
|
|
$ |
319,345 |
|
Short-term investments |
|
|
47,221 |
|
|
|
544,044 |
|
|
|
|
|
|
|
591,265 |
|
Accounts receivable, net |
|
|
384,480 |
|
|
|
5,915 |
|
|
|
(1,059 |
) |
|
|
389,336 |
|
Inventories, net |
|
|
143,452 |
|
|
|
8,350 |
|
|
|
(353 |
) |
|
|
151,449 |
|
Prepaid expenses and other current assets |
|
|
139,056 |
|
|
|
32,259 |
|
|
|
(2,087 |
) |
|
|
169,228 |
|
|
Total current assets |
|
|
1,010,723 |
|
|
|
613,399 |
|
|
|
(3,499 |
) |
|
|
1,620,623 |
|
Property, plant and equipment, net |
|
|
381,868 |
|
|
|
8,368 |
|
|
|
(237 |
) |
|
|
389,999 |
|
Goodwill and intangible assets, net |
|
|
309,264 |
|
|
|
4,794 |
|
|
|
|
|
|
|
314,058 |
|
Other long-term assets |
|
|
531,859 |
|
|
|
133,659 |
|
|
|
250 |
|
|
|
665,768 |
|
|
Total Assets |
|
$ |
2,233,714 |
|
|
$ |
760,220 |
|
|
$ |
(3,486 |
) |
|
$ |
2,990,448 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Liabilities and Stockholders Equity |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Current liabilities |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Accounts payable |
|
$ |
167,982 |
|
|
$ |
3,639 |
|
|
$ |
(2,610 |
) |
|
$ |
169,011 |
|
Accrued salaries and wages |
|
|
66,791 |
|
|
|
5,438 |
|
|
|
|
|
|
|
72,229 |
|
Current deferred tax liability |
|
|
17,045 |
|
|
|
|
|
|
|
|
|
|
|
17,045 |
|
Accrued taxes on income |
|
|
21,789 |
|
|
|
14,525 |
|
|
|
|
|
|
|
36,314 |
|
Other accrued expenses |
|
|
233,132 |
|
|
|
10,343 |
|
|
|
(741 |
) |
|
|
242,734 |
|
|
Total current liabilities |
|
|
506,739 |
|
|
|
33,945 |
|
|
|
(3,351 |
) |
|
|
537,333 |
|
Other long-term liabilities |
|
|
204,441 |
|
|
|
5,658 |
|
|
|
(254 |
) |
|
|
209,845 |
|
|
Total Liabilities |
|
|
711,180 |
|
|
|
39,603 |
|
|
|
(3,605 |
) |
|
|
747,178 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Total Stockholders Equity |
|
|
1,522,534 |
|
|
|
720,617 |
|
|
|
119 |
|
|
|
2,243,270 |
|
|
Total Liabilities and Stockholders Equity |
|
$ |
2,233,714 |
|
|
$ |
760,220 |
|
|
$ |
(3,486 |
) |
|
$ |
2,990,448 |
|
|
21
APPLERA CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
continued
Condensed Consolidating Statement of Cash Flows for the Six Months Ended December 31, 2006
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Applied |
|
|
|
|
|
|
|
|
|
|
|
|
Biosystems |
|
|
Celera |
|
|
|
|
|
|
|
(Dollar amounts in thousands) |
|
Group |
|
|
Group |
|
|
Eliminations |
|
|
Consolidated |
|
|
Operating Activities of Continuing Operations |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Net income (loss) |
|
$ |
16,060 |
|
|
$ |
(7,537 |
) |
|
$ |
(46 |
) |
|
$ |
8,477 |
|
Adjustments to reconcile net income (loss) to net cash
provided (used) by operating activities: |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Depreciation and amortization |
|
|
39,405 |
|
|
|
3,391 |
|
|
|
(150 |
) |
|
|
42,646 |
|
Asset impairments |
|
|
|
|
|
|
3,000 |
|
|
|
|
|
|
|
3,000 |
|
Employee-related charges and other |
|
|
|
|
|
|
3,013 |
|
|
|
|
|
|
|
3,013 |
|
Share-based compensation programs |
|
|
7,422 |
|
|
|
1,473 |
|
|
|
|
|
|
|
8,895 |
|
Deferred income taxes |
|
|
(3,960 |
) |
|
|
6,134 |
|
|
|
(1,465 |
) |
|
|
709 |
|
Sale of assets and legal settlements, net |
|
|
(209 |
) |
|
|
|
|
|
|
|
|
|
|
(209 |
) |
Acquired research and development |
|
|
114,251 |
|
|
|
|
|
|
|
|
|
|
|
114,251 |
|
Nonreimbursable utilization of intergroup tax benefits |
|
|
13,309 |
|
|
|
(13,309 |
) |
|
|
|
|
|
|
|
|
Changes in operating assets and liabilities: |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Accounts receivable |
|
|
(6,578 |
) |
|
|
3,711 |
|
|
|
329 |
|
|
|
(2,538 |
) |
Inventories |
|
|
(11,270 |
) |
|
|
(116 |
) |
|
|
353 |
|
|
|
(11,033 |
) |
Prepaid expenses and other assets |
|
|
(5,892 |
) |
|
|
(4,324 |
) |
|
|
(3,284 |
) |
|
|
(13,500 |
) |
Accounts payable and other liabilities |
|
|
(38,776 |
) |
|
|
(10,585 |
) |
|
|
4,217 |
|
|
|
(45,144 |
) |
|
Net Cash Provided (Used) by Operating Activities
of Continuing Operations |
|
|
123,762 |
|
|
|
(15,149 |
) |
|
|
(46 |
) |
|
|
108,567 |
|
|
Investing Activities of Continuing Operations |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Additions to property, plant and equipment, net |
|
|
(27,283 |
) |
|
|
(1,214 |
) |
|
|
46 |
|
|
|
(28,451 |
) |
Proceeds from maturities of available-for-sale investments |
|
|
|
|
|
|
130,745 |
|
|
|
|
|
|
|
130,745 |
|
Proceeds from sales of available-for-sale investments |
|
|
29,113 |
|
|
|
248,495 |
|
|
|
|
|
|
|
277,608 |
|
Purchases of available-for-sale investments |
|
|
(76,334 |
) |
|
|
(411,437 |
) |
|
|
|
|
|
|
(487,771 |
) |
Acquisitions and investments, net of cash acquired |
|
|
(121,403 |
) |
|
|
|
|
|
|
|
|
|
|
(121,403 |
) |
Proceeds from the sale of assets, net |
|
|
322 |
|
|
|
|
|
|
|
|
|
|
|
322 |
|
|
Net Cash Used by Investing Activities
of Continuing Operations |
|
|
(195,585 |
) |
|
|
(33,411 |
) |
|
|
46 |
|
|
|
(228,950 |
) |
|
Financing Activities |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Dividends |
|
|
(15,411 |
) |
|
|
|
|
|
|
|
|
|
|
(15,411 |
) |
Purchases of common stock for treasury |
|
|
(59,856 |
) |
|
|
|
|
|
|
|
|
|
|
(59,856 |
) |
Proceeds from stock issued for stock plans and other |
|
|
63,463 |
|
|
|
11,121 |
|
|
|
|
|
|
|
74,584 |
|
|
Net Cash Provided (Used) by Financing Activities |
|
|
(11,804 |
) |
|
|
11,121 |
|
|
|
|
|
|
|
(683 |
) |
|
Effect of Exchange Rate Changes on Cash |
|
|
6,220 |
|
|
|
|
|
|
|
|
|
|
|
6,220 |
|
|
Net Change in Cash and Cash Equivalents |
|
|
(77,407 |
) |
|
|
(37,439 |
) |
|
|
|
|
|
|
(114,846 |
) |
Cash and Cash Equivalents Beginning of Period |
|
|
373,921 |
|
|
|
60,270 |
|
|
|
|
|
|
|
434,191 |
|
|
Cash and Cash Equivalents End of Period |
|
$ |
296,514 |
|
|
$ |
22,831 |
|
|
$ |
|
|
|
$ |
319,345 |
|
|
22
APPLERA CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
continued
Condensed Consolidating Statement of Operations for the Three Months Ended December 31, 2005
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Applied |
|
|
|
|
|
|
|
|
|
|
|
|
Biosystems |
|
|
Celera |
|
|
|
|
|
|
|
(Dollar amounts in thousands) |
|
Group |
|
|
Group |
|
|
Eliminations |
|
Consolidated |
|
|
Products |
|
$ |
400,195 |
|
|
$ |
2,914 |
|
|
$ |
|
|
|
$ |
403,109 |
|
Services |
|
|
54,982 |
|
|
|
207 |
|
|
|
|
|
|
|
55,189 |
|
Other |
|
|
25,330 |
|
|
|
6,059 |
|
|
|
|
|
|
|
31,389 |
|
|
Net revenues from external customers |
|
|
480,507 |
|
|
|
9,180 |
|
|
|
|
|
|
|
489,687 |
|
Intersegment revenues |
|
|
1,409 |
|
|
|
1,068 |
|
|
|
(2,477 |
) |
|
|
|
|
|
Total Net Revenues |
|
|
481,916 |
|
|
|
10,248 |
|
|
|
(2,477 |
) |
|
|
489,687 |
|
|
Products |
|
|
193,626 |
|
|
|
2,839 |
|
|
|
(1,596 |
) |
|
|
194,869 |
|
Services |
|
|
23,055 |
|
|
|
1,653 |
|
|
|
(126 |
) |
|
|
24,582 |
|
Other |
|
|
2,718 |
|
|
|
707 |
|
|
|
|
|
|
|
3,425 |
|
|
Cost of Sales |
|
|
219,399 |
|
|
|
5,199 |
|
|
|
(1,722 |
) |
|
|
222,876 |
|
|
Gross Margin |
|
|
262,517 |
|
|
|
5,049 |
|
|
|
(755 |
) |
|
|
266,811 |
|
Selling, general and administrative |
|
|
125,052 |
|
|
|
6,712 |
|
|
|
12,855 |
|
|
|
144,619 |
|
Corporate allocated expenses |
|
|
10,808 |
|
|
|
2,051 |
|
|
|
(12,859 |
) |
|
|
|
|
Research, development and engineering |
|
|
45,170 |
|
|
|
28,699 |
|
|
|
(792 |
) |
|
|
73,077 |
|
Amortization of purchased intangible assets |
|
|
314 |
|
|
|
366 |
|
|
|
|
|
|
|
680 |
|
Employee-related charges, asset
impairments and other |
|
|
360 |
|
|
|
|
|
|
|
|
|
|
|
360 |
|
Asset dispositions and legal settlements |
|
|
3,032 |
|
|
|
|
|
|
|
|
|
|
|
3,032 |
|
|
Operating Income (Loss) |
|
|
77,781 |
|
|
|
(32,779 |
) |
|
|
41 |
|
|
|
45,043 |
|
Interest income, net |
|
|
3,233 |
|
|
|
5,922 |
|
|
|
|
|
|
|
9,155 |
|
Other income (expense), net |
|
|
1,240 |
|
|
|
(239 |
) |
|
|
|
|
|
|
1,001 |
|
|
Income (Loss) before Income Taxes |
|
|
82,254 |
|
|
|
(27,096 |
) |
|
|
41 |
|
|
|
55,199 |
|
Provision (benefit) for income taxes |
|
|
51,349 |
|
|
|
(9,765 |
) |
|
|
(470 |
) |
|
|
41,114 |
|
|
Net Income (Loss) |
|
$ |
30,905 |
|
|
$ |
(17,331 |
) |
|
$ |
511 |
|
|
$ |
14,085 |
|
|
23
APPLERA CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
continued
Condensed
Consolidating Statement of Operations for the Six Months Ended December 31, 2005
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Applied |
|
|
|
|
|
|
|
|
|
|
|
|
Biosystems |
|
|
Celera |
|
|
|
|
|
|
|
(Dollar amounts in thousands) |
|
Group |
|
|
Group |
|
|
Eliminations |
|
Consolidated |
|
|
Products |
|
$ |
736,003 |
|
|
$ |
5,635 |
|
|
$ |
|
|
|
$ |
741,638 |
|
Services |
|
|
106,425 |
|
|
|
1,031 |
|
|
|
|
|
|
|
107,456 |
|
Other |
|
|
52,054 |
|
|
|
10,767 |
|
|
|
|
|
|
|
62,821 |
|
|
Net revenues from external customers |
|
|
894,482 |
|
|
|
17,433 |
|
|
|
|
|
|
|
911,915 |
|
Intersegment revenues |
|
|
2,899 |
|
|
|
2,024 |
|
|
|
(4,923 |
) |
|
|
|
|
|
Total Net Revenues |
|
|
897,381 |
|
|
|
19,457 |
|
|
|
(4,923 |
) |
|
|
911,915 |
|
|
Products |
|
|
360,708 |
|
|
|
5,611 |
|
|
|
(3,243 |
) |
|
|
363,076 |
|
Services |
|
|
46,532 |
|
|
|
2,317 |
|
|
|
(278 |
) |
|
|
48,571 |
|
Other |
|
|
5,437 |
|
|
|
1,622 |
|
|
|
|
|
|
|
7,059 |
|
|
Total Cost of Sales |
|
|
412,677 |
|
|
|
9,550 |
|
|
|
(3,521 |
) |
|
|
418,706 |
|
|
Gross Margin |
|
|
484,704 |
|
|
|
9,907 |
|
|
|
(1,402 |
) |
|
|
493,209 |
|
Selling, general and administrative |
|
|
237,264 |
|
|
|
14,651 |
|
|
|
24,569 |
|
|
|
276,484 |
|
Corporate allocated expenses |
|
|
20,579 |
|
|
|
3,994 |
|
|
|
(24,573 |
) |
|
|
|
|
Research, development and engineering |
|
|
86,008 |
|
|
|
58,251 |
|
|
|
(1,485 |
) |
|
|
142,774 |
|
Amortization of purchased intangible assets |
|
|
628 |
|
|
|
1,091 |
|
|
|
|
|
|
|
1,719 |
|
Employee-related charges, asset
impairments, and other |
|
|
1,231 |
|
|
|
|
|
|
|
|
|
|
|
1,231 |
|
Asset dispositions and legal settlements |
|
|
25,866 |
|
|
|
675 |
|
|
|
|
|
|
|
26,541 |
|
|
Operating Income (Loss) |
|
|
113,128 |
|
|
|
(68,755 |
) |
|
|
87 |
|
|
|
44,460 |
|
Gain on investments, net |
|
|
|
|
|
|
4,503 |
|
|
|
|
|
|
|
4,503 |
|
Interest income, net |
|
|
7,655 |
|
|
|
11,170 |
|
|
|
|
|
|
|
18,825 |
|
Other income (expense), net |
|
|
2,905 |
|
|
|
(197 |
) |
|
|
|
|
|
|
2,708 |
|
|
Income (Loss) before Income Taxes |
|
|
123,688 |
|
|
|
(53,279 |
) |
|
|
87 |
|
|
|
70,496 |
|
Provision (benefit) for income taxes |
|
|
49,659 |
|
|
|
(19,200 |
) |
|
|
773 |
|
|
|
31,232 |
|
|
Net Income (Loss) |
|
$ |
74,029 |
|
|
$ |
(34,079 |
) |
|
$ |
(686 |
) |
|
$ |
39,264 |
|
|
24
APPLERA CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
continued
Condensed Consolidating Statement of Financial Position at June 30, 2006
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Applied |
|
|
|
|
|
|
|
|
|
|
|
|
Biosystems |
|
|
Celera |
|
|
|
|
|
|
|
(Dollar amounts in thousands) |
|
Group |
|
|
Group |
|
|
Eliminations |
|
|
Consolidated |
|
|
Assets |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Current assets |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Cash and cash equivalents |
|
$ |
373,921 |
|
|
$ |
60,270 |
|
|
$ |
|
|
|
$ |
434,191 |
|
Short-term investments |
|
|
|
|
|
|
509,252 |
|
|
|
|
|
|
|
509,252 |
|
Accounts receivable, net |
|
|
373,613 |
|
|
|
9,626 |
|
|
|
(730 |
) |
|
|
382,509 |
|
Inventories, net |
|
|
129,417 |
|
|
|
8,234 |
|
|
|
|
|
|
|
137,651 |
|
Prepaid expenses and other current assets |
|
|
135,711 |
|
|
|
32,966 |
|
|
|
(5,315 |
) |
|
|
163,362 |
|
|
Total current assets |
|
|
1,012,662 |
|
|
|
620,348 |
|
|
|
(6,045 |
) |
|
|
1,626,965 |
|
Property, plant and equipment, net |
|
|
387,170 |
|
|
|
9,607 |
|
|
|
(341 |
) |
|
|
396,436 |
|
Goodwill and intangible assets, net |
|
|
316,269 |
|
|
|
5,828 |
|
|
|
|
|
|
|
322,097 |
|
Other long-term assets |
|
|
529,671 |
|
|
|
137,895 |
|
|
|
(89 |
) |
|
|
667,477 |
|
|
Total Assets |
|
$ |
2,245,772 |
|
|
$ |
773,678 |
|
|
$ |
(6,475 |
) |
|
$ |
3,012,975 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Liabilities and Stockholders Equity |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Current liabilities |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Accounts payable |
|
$ |
200,591 |
|
|
$ |
6,497 |
|
|
$ |
(5,397 |
) |
|
$ |
201,691 |
|
Accrued salaries and wages |
|
|
89,883 |
|
|
|
9,055 |
|
|
|
|
|
|
|
98,938 |
|
Current deferred tax liability |
|
|
17,560 |
|
|
|
|
|
|
|
|
|
|
|
17,560 |
|
Accrued taxes on income |
|
|
38,157 |
|
|
|
12,787 |
|
|
|
|
|
|
|
50,944 |
|
Other accrued expenses |
|
|
227,001 |
|
|
|
13,089 |
|
|
|
(933 |
) |
|
|
239,157 |
|
|
Total current liabilities |
|
|
573,192 |
|
|
|
41,428 |
|
|
|
(6,330 |
) |
|
|
608,290 |
|
Other long-term liabilities |
|
|
194,844 |
|
|
|
5,817 |
|
|
|
(310 |
) |
|
|
200,351 |
|
|
Total Liabilities |
|
|
768,036 |
|
|
|
47,245 |
|
|
|
(6,640 |
) |
|
|
808,641 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Total Stockholders Equity |
|
|
1,477,736 |
|
|
|
726,433 |
|
|
|
165 |
|
|
|
2,204,334 |
|
|
Total Liabilities and Stockholders Equity |
|
$ |
2,245,772 |
|
|
$ |
773,678 |
|
|
$ |
(6,475 |
) |
|
$ |
3,012,975 |
|
|
25
APPLERA CORPORATION
NOTES TO UNAUDITED CONDENSED CONSOLIDATED FINANCIAL STATEMENTS
continued
Condensed Consolidating Statement of Cash Flows for the Six Months Ended December 31, 2005
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Applied |
|
|
|
|
|
|
|
|
|
|
|
|
Biosystems |
|
|
Celera |
|
|
|
|
|
|
|
(Dollar amounts in thousands) |
|
Group |
|
|
Group |
|
|
Eliminations |
|
|
Consolidated |
|
|
Operating Activities of Continuing Operations |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Net income (loss) |
|
$ |
74,029 |
|
|
$ |
(34,079 |
) |
|
$ |
(686 |
) |
|
$ |
39,264 |
|
Adjustments to reconcile net income (loss) to net cash |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
provided (used) by operating activities: |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Depreciation and amortization |
|
|
37,950 |
|
|
|
8,320 |
|
|
|
(222 |
) |
|
|
46,048 |
|
Asset impairments |
|
|
1,090 |
|
|
|
|
|
|
|
|
|
|
|
1,090 |
|
Employee-related charges and other |
|
|
(1,409 |
) |
|
|
|
|
|
|
|
|
|
|
(1,409 |
) |
Share-based compensation programs |
|
|
3,792 |
|
|
|
645 |
|
|
|
|
|
|
|
4,437 |
|
Deferred income taxes |
|
|
(11,266 |
) |
|
|
4,608 |
|
|
|
331 |
|
|
|
(6,327 |
) |
Sale of assets and legal settlements, net |
|
|
26,758 |
|
|
|
(3,820 |
) |
|
|
|
|
|
|
22,938 |
|
Nonreimbursable utilization of intergroup tax benefits |
|
|
19,135 |
|
|
|
(19,135 |
) |
|
|
|
|
|
|
|
|
Changes in operating assets and liabilities: |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Accounts receivable |
|
|
32,133 |
|
|
|
(630 |
) |
|
|
(109 |
) |
|
|
31,394 |
|
Inventories |
|
|
(7,326 |
) |
|
|
(300 |
) |
|
|
|
|
|
|
(7,626 |
) |
Prepaid expenses and other assets |
|
|
429 |
|
|
|
(2,553 |
) |
|
|
(284 |
) |
|
|
(2,408 |
) |
Accounts payable and other liabilities |
|
|
10,284 |
|
|
|
(13,934 |
) |
|
|
888 |
|
|
|
(2,762 |
) |
|
Net Cash Provided (Used) by Operating Activities
of Continuing Operations |
|
|
185,599 |
|
|
|
(60,878 |
) |
|
|
(82 |
) |
|
|
124,639 |
|
|
Investing Activities of Continuing Operations |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Additions to property, plant and equipment, net |
|
|
(23,348 |
) |
|
|
(2,550 |
) |
|
|
151 |
|
|
|
(25,747 |
) |
Proceeds from maturities of available-for-sale investments |
|
|
|
|
|
|
75,983 |
|
|
|
|
|
|
|
75,983 |
|
Proceeds from sales of available-for-sale investments |
|
|
81,214 |
|
|
|
145,931 |
|
|
|
|
|
|
|
227,145 |
|
Purchases of available-for-sale investments |
|
|
(84,409 |
) |
|
|
(165,691 |
) |
|
|
|
|
|
|
(250,100 |
) |
Acquisitions and investments, net of cash acquired |
|
|
(1,235 |
) |
|
|
|
|
|
|
|
|
|
|
(1,235 |
) |
Proceeds from the sale of assets, net |
|
|
|
|
|
|
4,572 |
|
|
|
(69 |
) |
|
|
4,503 |
|
|
Net Cash Provided (Used) by Investing Activities
of Continuing Operations |
|
|
(27,778 |
) |
|
|
58,245 |
|
|
|
82 |
|
|
|
30,549 |
|
|
Financing Activities |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Dividends |
|
|
(8,253 |
) |
|
|
|
|
|
|
|
|
|
|
(8,253 |
) |
Net cash funding from groups |
|
|
(4,356 |
) |
|
|
4,356 |
|
|
|
|
|
|
|
|
|
Purchases of common stock for treasury |
|
|
(457,120 |
) |
|
|
|
|
|
|
|
|
|
|
(457,120 |
) |
Proceeds from stock issued for stock plans and other |
|
|
63,664 |
|
|
|
6,768 |
|
|
|
|
|
|
|
70,432 |
|
|
Net Cash Provided (Used) by Financing Activities |
|
|
(406,065 |
) |
|
|
11,124 |
|
|
|
|
|
|
|
(394,941 |
) |
|
Effect of Exchange Rate Changes on Cash |
|
|
(8,668 |
) |
|
|
|
|
|
|
|
|
|
|
(8,668 |
) |
|
Net Change in Cash and Cash Equivalents |
|
|
(256,912 |
) |
|
|
8,491 |
|
|
|
|
|
|
|
(248,421 |
) |
Cash and Cash Equivalents Beginning of Period |
|
|
756,236 |
|
|
|
23,165 |
|
|
|
|
|
|
|
779,401 |
|
|
Cash and Cash Equivalents End of Period |
|
$ |
499,324 |
|
|
$ |
31,656 |
|
|
$ |
|
|
|
$ |
530,980 |
|
|
26
Item 2. Managements Discussion and Analysis of Financial Condition and Results of Operations.
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS
The purpose of the following managements discussion and analysis is to provide an overview of the
business of Applera Corporation to help facilitate an understanding of significant factors
influencing our historical operating results, financial condition, and cash flows and also to
convey our expectations of the potential impact of known trends, events, or uncertainties that may
impact our future results. You should read this discussion in conjunction with our consolidated
financial statements and related notes included in this report and in our 2006 Annual Report to
Stockholders. Historical results and percentage relationships are not necessarily indicative of
operating results for future periods. When used in this management discussion, the terms
Applera, Company, we, us, or our mean Applera Corporation and its subsidiaries.
We have reclassified some prior year amounts in the condensed consolidated financial statements and
notes for comparative purposes.
Overview
We conduct business through two business segments: the Applied Biosystems group and the Celera
group.
The Applied Biosystems group serves the life science industry and research community by developing
and marketing instrument-based systems, consumables, software, and services. Its customers use
these tools to analyze nucleic acids (DNA and RNA), small molecules, and proteins to make
scientific discoveries and develop new pharmaceuticals. The Applied Biosystems groups products
also serve the needs of some markets outside of life science research, which we refer to as
applied markets, such as the fields of: human identity testing (forensic and paternity testing);
biosecurity, which refers to products needed in response to the threat of biological terrorism
and other malicious, accidental, and natural biological dangers; and quality and safety testing,
for example in food and the environment.
The Celera group is primarily a molecular diagnostics business that is using proprietary genomics
and proteomics discovery platforms to identify and validate novel diagnostic markers, and is
developing diagnostic products based on these markers as well as other known markers. The Celera
group maintains a strategic alliance with Abbott Laboratories for the development and
commercialization of molecular, or nucleic acid-based, diagnostic products, and it is also
developing new diagnostic products outside of this alliance. Through its genomics and proteomics
research efforts, the Celera group is also discovering and validating therapeutic targets, and it
is seeking strategic partnerships to develop therapeutic products based on these discovered
targets. Effective December 1, 2006, we changed the name of our Celera Genomics group to Celera
group to better reflect the Celera groups focus and business strategy.
From April 2001 through December 31, 2005, we operated a diagnostic business known as Celera
Diagnostics. This business was a 50/50 joint venture between the Applied Biosystems group and the
Celera group. Effective January 1, 2006, the Celera group acquired the Applied Biosystems groups
50 percent interest in the Celera Diagnostics joint venture such that it now owns 100 percent of
Celera Diagnostics. As a result of this restructuring and the manner by which our management now
operates and assesses our businesses, Celera Diagnostics is no longer a separate segment within
Applera and we have restated prior period consolidating financial information to reflect this
change. Celera Diagnostics was focused on the discovery, development, and commercialization of
diagnostic products. As part of the Celera group, the diagnostics business continues to focus on
these areas.
In fiscal 1999, as part of a recapitalization of our Company, we created two classes of common
stock referred to as tracking stocks. Tracking stock is a class of stock of a corporation
intended to track or reflect the relative performance of a specific business within the
corporation.
27
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
Applera Corporation-Applied Biosystems Group Common Stock (Applera-Applied Biosystems stock) is
listed on the New York Stock Exchange under the ticker symbol ABI and is intended to reflect the
relative performance of the Applied Biosystems group. Applera Corporation-Celera Group Common
Stock (Applera-Celera stock) is listed on the New York Stock Exchange under the ticker symbol
CRA and is intended to reflect the relative performance of the Celera group. There is no single
security that represents the performance of Applera as a whole, nor was there a separate security
traded for Celera Diagnostics.
Holders of Applera-Applied Biosystems stock and holders of Applera-Celera stock are stockholders of
Applera. The Applied Biosystems group and the Celera group are not separate legal entities, and
holders of these stocks are stockholders of a single company, Applera. As a result, holders of
these stocks are subject to all of the risks associated with an investment in Applera and all of
its businesses, assets, and liabilities. The Applied Biosystems group and the Celera group do not
have separate boards of directors. Applera has one board of directors, which will make any
decision in accordance with its good faith business judgment that the decision is in the best
interests of Applera and all of its stockholders as a whole.
More information about the risks relating to our capital structure, particularly our two classes of
capital stock, is contained in our Annual Report on Form 10-K for fiscal 2006 filed with the
Securities and Exchange Commission.
Our fiscal year ends on June 30. The financial information for both segments is presented in Note
13 to our condensed consolidated financial statements, Segment and Consolidating Information.
Managements discussion and analysis addresses the consolidated financial results followed by the
discussions of our two segments.
Business Developments:
Applied Biosystems Group
|
|
In January 2007, the Applied Biosystems group announced the
worldwide availability of its StepOne Real-Time PCR system.
The StepOne system was developed in response to the growing
market of researchers interested in lower throughput
applications of real-time PCR. The StepOne system
complements the Applied Biosystems groups comprehensive
portfolio of real-time PCR instruments for high and
mid-throughput applications, providing life scientists with a
variety of systems that are appropriate for their particular
laboratory environment and budget. |
|
|
|
Also in January 2007, the Applied Biosystems group announced
the release of a new series of TaqMan® Gene
Signature Panels for accelerating drug discovery research.
The TaqMan Low Density Array Gene Signature Panels enable
researchers to simultaneously observe and determine the
expression level of genes that encode proteins involved with
critical cellular functions. Researchers who use these gene
signature panels will be able to more thoroughly study
difficult-to-detect genes that are important to the drug
research needs of the pharmaceutical industry. |
Celera Group
|
|
Innogenetics N.V., Ghent, Belgium, brought a patent
infringement suit against Abbott Laboratories, our alliance
partner, in September 2005 regarding Abbotts hepatitis C
virus (HCV) genotyping products. In September 2006, a jury
in Madison, Wisconsin found that the sale of these products
willfully infringed a U.S. patent owned by Innogenetics and awarded Innogenetics $7.0 million in damages. In
January 2007, the U.S. District Court for the Western
District of Wisconsin ruled in favor of Innogenetics request
for a permanent injunction, and as such, ordered Abbott to
withdraw its products from the market. The Court also
reversed the jury verdict of willful infringement and ruled
that Abbott did not willfully infringe Innogenetics patent
and denied Innogenetics request for enhanced damages and
attorneys fees. Innogenetics did not name the Celera group
as a party in this lawsuit, but the Celera group has an
interest in these products and in the outcome of the
litigation because the enjoined products are manufactured by
the Celera group and sold through its alliance with Abbott. Also, as
these products are part of its alliance with Abbott, the Celera group
has agreed to share the cost of this litigation, including the damage
award described above. Abbott has informed the Celera group that it will appeal the
judgment as both Abbott and
the Celera group believe that Innogenetics patent is invalid and that the alliances HCV
genotyping analyte specific |
28
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
|
|
reagents (ASRs) do not infringe Innogenetics patent. Abbott has filed an
emergency motion with the Court of Appeals for the Federal Circuit
seeking a stay of the permanent injunction during the appeal process.
On January 19, 2007, Abbott obtained a temporary stay of the injunction from the Court pending the
Courts consideration of the emergency motion for a stay of the permanent injunction. |
|
|
|
In January 2007, Health Canada approved the Abbott m2000
instrument system and the Abbott RealTime HIV-1 and
HCV viral load tests for marketing in Canada. This is the first
HIV-1 viral load assay approved by Health Canada that can detect
and accurately measure HIV-1 group M, group O and group N
subtypes. |
|
|
|
In December 2006, the Celera group published findings in the
American Journal of Human Genetics (AJHG) that variants in two
genes (IL12B and IL23R) involved in regulating the behavior of
cells of the immune system independently contribute to psoriasis
risk. These findings provide genetic evidence to support the
ongoing development of therapeutics that target the interleukin-12
and interleukin-23 (IL-12 and IL-23) pathways. This publication
will appear in the February 2007 print edition of AJHG. |
|
|
|
In November 2006, the Celera group and its collaborators presented
results from two studies as part of the scientific sessions at the
American Heart Association 2006 meeting in Chicago, IL. One study
was from the Atherosclerosis Risk in Communities (ARIC) study
describing progress in the development of an initial combination
of genetic variants that predicts risk for coronary heart disease
(CHD), and the other described the association of one of these
variants (VAMP8) with CHD in the Johns Hopkins Sibling Study. |
Critical Accounting Estimates
There were no material changes to our critical accounting estimates during the first six months of
fiscal 2007. For further information on our critical accounting estimates, refer to the discussion
contained in the managements discussion and analysis section of our 2006 Annual Report to
Stockholders (which discussion is incorporated in this quarterly report by reference).
Events Impacting Comparability
We are providing the following information on some actions taken by us or events that occurred in
the periods indicated. We describe the effect of these items on our reported earnings for the
purpose of providing you with a better understanding of our on-going operations. You should
consider these items when making comparisons to past performance and assessing prospects for future
results.
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Three months ended |
|
|
Six months ended |
|
Income/(charge) |
|
December 31, |
|
|
December 31, |
(Dollar amounts in millions) |
|
2006 |
|
|
2005 |
|
|
2006 |
|
|
2005 |
|
|
Severance and benefit costs |
|
$ |
|
|
|
$ |
(1.5 |
) |
|
$ |
|
|
|
$ |
(1.5 |
) |
Asset impairments |
|
|
(3.0 |
) |
|
|
|
|
|
|
(3.0 |
) |
|
|
(1.1 |
) |
Other |
|
|
(0.1 |
) |
|
|
|
|
|
|
(3.6 |
) |
|
|
|
|
Reduction of expected costs |
|
|
0.6 |
|
|
|
1.2 |
|
|
|
0.6 |
|
|
|
1.4 |
|
|
Total employee-related charges, asset
impairments and other |
|
$ |
(2.5 |
) |
|
$ |
(0.3 |
) |
|
$ |
(6.0 |
) |
|
$ |
(1.2 |
) |
|
Other events impacting comparability: |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Revenue from sale of small molecule program |
|
$ |
2.5 |
|
|
$ |
|
|
|
$ |
2.5 |
|
|
$ |
|
|
Asset dispositions and legal settlements |
|
|
10.2 |
|
|
|
(3.1 |
) |
|
|
1.1 |
|
|
|
(26.6 |
) |
Acquired research and development |
|
|
|
|
|
|
|
|
|
|
(114.3 |
) |
|
|
|
|
Investment gains |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
4.5 |
|
Tax items |
|
|
1.0 |
|
|
|
(28.0 |
) |
|
|
9.8 |
|
|
|
(14.5 |
) |
|
Acquisition
In July 2006, we acquired Agencourt Personal Genomics, Inc. (APG) for approximately $121 million
in cash, including transaction costs. At the time of the purchase, APG was a privately-held
developer of next-generation genetic analysis technology. APGs proprietary technology was based
on stepwise ligation, a novel and very high throughput approach to DNA analysis. We allocated this
transaction to the Applied Biosystems group.
29
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
In
accordance with Statement of Financial Accounting Standards
(SFAS) No. 141, Business Combinations, we
accounted for this transaction as a purchase of assets rather than a
business combination since APG did not meet the definition of a business as defined by Emerging Issues Task
Force (EITF) Abstracts Issue 98-3, Determining Whether
a Nonmonetary Transaction Involves Receipt of Productive Assets or of a Business. The key
considerations impacting our accounting determination were that APG was primarily focused on
research and development activities, had not commenced principal operations, and did not have
products, customers or revenues. For further information on the purchase of APG, see Note 3 to our
condensed consolidated financial statements.
Acquired Research and Development
In the first quarter of fiscal 2007, the Applied Biosystems group recorded a $114.3 million charge
to write-off the value of acquired in-process research and development (IPR&D) in connection with
the acquisition of APG. As of the acquisition date, the technological
feasibility of the acquired IPR&D project had not been established, and it was determined that the project had no future
alternative use. The project being developed, which consists of both an instrument and reagents,
is intended for very high throughput genetic analysis applications, including DNA sequencing and
expression profiling.
At the date of acquisition, the project was in the development stage and approximately 30%
complete. The remaining efforts for the instrument are currently focused on developing and
converting the prototype instrument to a manufactured instrument that can be shipped
internationally. We expect the overall throughput of the instrument to be increased significantly
from the prototype instrument before the commercial launch. The remaining efforts for the reagents
are currently focused on developing reagents that can be manufactured at scale and produce results
that can be reproduced in customer laboratories. The nature and timing of these remaining efforts
are dependent on successful internal testing of both the instrument and the reagents. The
following table briefly describes the APG project.
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
At Acquisition Date |
|
|
At December 31, 2006 |
|
|
|
|
|
|
|
|
|
|
Approximate |
|
|
|
|
|
|
Approximate |
|
|
Fair |
|
Estimated Costs |
|
Percentage |
|
|
Estimated Costs |
|
Percentage |
(Dollar amounts in millions) |
|
Value |
|
to Complete |
|
Completed |
|
|
to Complete |
|
Completed |
|
|
|
|
Instruments |
|
$ |
66.6 |
|
|
$ |
10.0 |
|
|
|
35 |
% |
|
|
$ |
10.8 |
|
|
|
45 |
% |
|
|
|
|
|
|
Reagents |
|
|
47.7 |
|
|
|
6.0 |
|
|
|
25 |
% |
|
|
|
6.2 |
|
|
|
35 |
% |
|
|
|
|
|
|
|
|
|
|
Total |
|
$ |
114.3 |
|
|
$ |
16.0 |
|
|
|
|
|
|
|
$ |
17.0 |
|
|
|
|
|
|
|
|
|
The initial instrument and reagents are expected to begin generating revenue in fiscal 2008.
Enhanced platforms are expected to begin generating revenues in fiscal 2010 and fiscal 2013. As of
December 31, 2006, the total project costs are expected to be approximately $25 million. The
increase in costs to complete the project is expected to be substantially offset by reductions to
other planned R&D projects.
At the time of the filing of this report, we do not anticipate any delays in our development
timeline; however, unanticipated difficulties or delays in developing and bringing this project to
market could harm the Applied Biosystems groups future operating results. At the time of the
acquisition, we believed there was a reasonable chance of realizing the economic return expected
from the acquired in-process technology. However, as there is risk associated with the realization
of benefits related to commercialization of an in-process project due to, among other things,
rapidly changing customer needs, the complexity of the technology, growing competitive pressures,
and potentially conflicting intellectual property rights of third parties, there can be no
assurance that any project will meet commercial success. Failure to successfully commercialize an
in-process project would result in the loss of the expected economic return inherent in the fair
value allocation.
Employee-Related Charges, Asset Impairments and Other
The following items have been recorded in the condensed consolidated statements of operations in
employee-related charges, asset impairments and other, except as noted.
30
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
Applied Biosystems group
Fiscal 2006
In the second quarter of fiscal 2006, the Applied Biosystems group recorded pre-tax charges of $1.5
million for employee terminations related to the Applied Biosystems/MDS Sciex Instruments joint
venture, a 50/50 joint venture between the Applied Biosystems group and MDS Inc. MDS recorded a
restructuring charge for a reduction in workforce as part of its strategy to focus on the life
sciences market. The $1.5 million represented the Applied Biosystems groups share of the
restructuring charge.
The Applied Biosystems group recorded pre-tax benefits of $1.2 million in the second quarter and
$1.4 million in the first six months of fiscal 2006 for reductions in anticipated employee-related
costs associated with severance and benefit charges recorded in fiscal 2005.
In the first quarter of fiscal 2006, the Applied Biosystems group recorded a $1.1 million pre-tax
impairment charge to write-down the carrying amount of its San Jose, California facility to its
estimated market value at that time less estimated selling costs. This charge was in addition to a
charge recorded in fiscal 2005. In the fourth quarter of fiscal 2006, the Applied Biosystems group
completed the sale and recognized a $0.9 million pre-tax favorable adjustment to the charges
previously recorded based on the actual sales price.
Other fiscal
2007 cash payments
During the first six months of fiscal 2007, the Applied Biosystems group made cash payments of $0.8
million for severance and employee benefits and office closures related to charges recorded prior
to fiscal 2006. The following table summarizes the remaining cash payments by event and the
expected payment dates as of December 31, 2006.
|
|
|
|
|
|
|
|
|
(Dollar amounts in millions) |
|
Remaining cash payments |
|
|
Expected payment dates |
|
Fiscal 2003 employee-related charge |
|
$ |
0.3 |
|
|
Fiscal 2008 |
Fiscal 2005 employee-related charge |
|
|
0.1 |
|
|
Fiscal 2007 |
Fiscal 2005 excess lease space and other charges |
|
|
1.1 |
|
|
Fiscal 2007 Fiscal 2011 |
|
|
|
|
|
|
|
|
|
|
$ |
1.5 |
|
|
|
|
|
|
Celera group
Fiscal 2007
During the second quarter of fiscal 2007, the Celera group recorded a pre-tax charge of $2.5
million, which was primarily comprised of a $3.0 million pre-tax charge for the write-down of the
carrying amount of an owned facility that was impaired initially in fiscal 2006, partially offset
by a pre-tax benefit of $0.6 million for a reduction in anticipated employee-related costs
associated with severance and benefit charges recorded in the third and fourth quarters of fiscal
2006. Both of these items are discussed below.
During the first quarter of fiscal 2007, the Celera group recorded a pre-tax charge of $3.5 million
for its estimated share of a damage award in continuing litigation between Abbott Laboratories, our
alliance partner, and Innogenetics N.V. In September 2006, a jury found that the sale of HCV
genotyping ASR products by Abbott willfully infringed a U.S. patent owned by Innogenetics and
awarded Innogenetics $7.0 million in damages. In January 2007, the U.S. District Court for the
Western District of Wisconsin ruled in favor of Innogenetics request for a permanent injunction,
and as such, ordered Abbott to withdraw its products from the market. The Court also reversed the
jury verdict of willful infringement and ruled that Abbott did not willfully infringe Innogenetics
patent and denied Innogenetics request for enhanced damages and attorneys fees. Innogenetics did
not name the Celera group as a party in this lawsuit, but the Celera group has an interest in these
products and in the outcome of the litigation because the enjoined products are manufactured by the
Celera group and sold through its alliance with Abbott. Also, as these products are part of its
alliance with Abbott, the Celera group has agreed to share the cost of this litigation, including
the damage award described above. Abbott has informed the Celera group that it will appeal the
judgment as both Abbott and the Celera group believe that Innogenetics patent is invalid and that
the alliances HCV genotyping ASRs do not infringe Innogenetics patent. Abbott has filed an
emergency motion with the Court of Appeals for the Federal Circuit seeking a stay of the permanent
injunction during the
31
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
appeal process. Also, on January 19, 2007, Abbott obtained a temporary stay of the injunction from the Court pending the Courts consideration of the emergency motion for a stay of the permanent injunction.
Fiscal 2006
During fiscal 2006, the Celera group recorded pre-tax charges related to its decision to exit its
small molecule drug discovery and development programs and the integration of Celera Diagnostics
into the Celera group. These charges consisted of the following components:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Employee- |
|
|
|
|
|
|
Excess |
|
|
Other |
|
|
|
|
|
|
Related |
|
|
Asset |
|
|
Lease |
|
|
Disposal |
|
|
|
|
(Dollar amounts in millions) |
|
Charges |
|
|
Impairments |
|
|
Space |
|
|
Costs |
|
|
Total |
|
|
Third quarter |
|
$ |
10.7 |
|
|
$ |
8.0 |
|
|
$ |
0.8 |
|
|
$ |
1.4 |
|
|
$ |
20.9 |
|
Fourth quarter |
|
|
2.1 |
|
|
|
1.8 |
|
|
|
0.4 |
|
|
|
1.2 |
|
|
|
5.5 |
|
|
Total charges |
|
|
12.8 |
|
|
|
9.8 |
|
|
|
1.2 |
|
|
|
2.6 |
|
|
|
26.4 |
|
|
Cash payments |
|
|
7.9 |
|
|
|
|
|
|
|
0.2 |
|
|
|
2.4 |
|
|
|
10.5 |
|
Non-cash activity |
|
|
|
|
|
|
9.3 |
|
|
|
|
|
|
|
0.2 |
|
|
|
9.5 |
|
|
Balance at June 30, 2006 |
|
|
4.9 |
|
|
|
0.5 |
|
|
|
1.0 |
|
|
|
|
|
|
|
6.4 |
|
|
Additional charge |
|
|
|
|
|
|
3.0 |
|
|
|
|
|
|
|
|
|
|
|
3.0 |
|
|
Non-cash activity |
|
|
|
|
|
|
3.0 |
|
|
|
|
|
|
|
|
|
|
|
3.0 |
|
Cash payments |
|
|
4.1 |
|
|
|
|
|
|
|
0.7 |
|
|
|
|
|
|
|
4.8 |
|
Reduction of expected costs |
|
|
0.6 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
0.6 |
|
|
Balance at December 31, 2006 |
|
$ |
0.2 |
|
|
$ |
0.5 |
|
|
$ |
0.3 |
|
|
$ |
|
|
|
$ |
1.0 |
|
|
The employee-related charges were severance costs primarily for staff reductions in small molecule
drug discovery and development. All of the affected employees were notified and terminated by
September 30, 2006. In the second quarter of fiscal 2007, the Celera group recorded a pre-tax
benefit of $0.6 million for a reduction in anticipated employee-related costs associated with the
severance and benefit charges recorded in the third and fourth quarters of fiscal 2006.
The asset impairment charges primarily related to a write-down of the carrying amount of an owned
facility to its current estimated market value less estimated selling costs, as well as write-offs
of leasehold improvements and equipment. This facility was reclassified into assets held for sale
in fiscal 2006. In the second quarter of fiscal 2007, the Celera group recorded an additional $3.0
million pre-tax, non-cash charge to write-down the carrying amount of this facility.
Cash expenditures for these charges were funded by available cash. We believe these actions will
enable the Celera group to focus on its molecular diagnostics and proteomics activities, reduce
cash consumption, and accelerate its move toward profitability, in part due to lower R&D expenses.
The remaining cash expenditures related to these charges are expected to be disbursed by December
31, 2007.
Other fiscal 2007 cash payments
During the first six months of fiscal 2007, the Celera group made net cash payments of
approximately $0.8 million related to an excess facility lease space charge that was recorded prior
to fiscal 2006. The remaining net cash expenditures of approximately $3.5 million related to this
charge, which reflected an adjustment in the second quarter of fiscal 2007, are expected to be
disbursed by fiscal 2011.
Other Events Impacting Comparability
Revenue from sale of small molecule program
In the second quarter of fiscal 2007, the Celera group recorded a pre-tax gain of $2.5 million in
net revenues from the sale of a small molecule drug discovery and development program to Schering
AG, which represented the remaining balance for this transaction. The Celera group recorded $2.5
million in the fourth quarter of fiscal 2006 when the agreement for
the sale of the program was executed.
32
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
Asset dispositions and legal settlements
The following items have been recorded in the condensed consolidated statements of operations in
asset dispositions and legal settlements.
Fiscal 2007
In the second quarter of fiscal 2007, the Applied Biosystems group recorded a $4.8 million pre-tax
benefit related to the settlement of a patent infringement claim and a $3.0 million pre-tax benefit
related to our collection from a third party of a portion of its liability relative to our
settlement of a prior legal dispute. Additionally in the second quarter of fiscal 2007, the Celera
group recorded a $2.4 million pre-tax benefit related to the settlement of a litigation matter
associated with the former Online/Information Business, an information products and service
business.
In the first quarter of fiscal 2007, the Applied Biosystems group recorded a $9.1 million pre-tax
charge related to a settlement agreement entered into with another company which resolved
outstanding legal disputes with that company.
Fiscal 2006
In the first quarter of fiscal 2006, we recorded a $23.5 million pre-tax charge related to a
litigation matter and an award in an arbitration proceeding with Amersham Biosciences, now GE
Healthcare. We recorded the pre-tax charge as follows: $22.8 million at the Applied Biosystems
group and $0.7 million at the Celera group. The arbitrator awarded Amersham past damages based on
an increase in royalty rates for some of its DNA sequencing enzymes and kits that contain those
enzymes, plus interest, fees, and other costs. As a result of this decision, the Applied
Biosystems group recorded a pre-tax charge of $20.4 million in the first quarter of fiscal 2006,
$19.5 million of which was recorded in asset dispositions and legal settlements. In the second
quarter of fiscal 2006, we recorded an additional pre-tax charge of $3.1 million at the Applied
Biosystems group as a result of the final determination of interest related to the arbitration
award. We paid all amounts related to the arbitration matter in January 2006.
Investments
In the first quarter of fiscal 2006, the Celera group recorded a pre-tax gain of $4.5 million in
the condensed consolidated statements of operations in gain on investments, net from the sale of a
non-strategic minority equity investment.
Tax items
Fiscal 2007
In December 2006, the President of the U.S. signed the Tax Relief and Health Care Act of 2006,
which extended the R&D tax credit from January 1, 2006 through December 31, 2007. The Celera group
included the estimated benefit of the current year R&D tax credit in the second quarter of fiscal
2007 estimated annual effective tax rate. In addition, the Celera group recorded a tax benefit of
$1.0 million in the second quarter of fiscal 2007 related to the R&D tax credit generated between
January 1, 2006 to June 30, 2006. In the first quarter of fiscal 2007, the Applied Biosystems
group recorded a tax benefit of $8.8 million related to a reduction in the valuation allowance for
some German net operating loss carryforwards.
Fiscal 2006
In the first quarter of fiscal 2006, the Applied Biosystems group recorded a tax benefit of $13.5
million related to the resolution of transfer pricing matters in Japan. During the second quarter
of fiscal 2006, the Applied Biosystems group recorded tax charges of $28.0 million related to
repatriation of cash balances held outside the U.S.
33
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
Discussion of Applera Corporations Consolidated Operations
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Three Months Ended |
|
|
Six Months Ended |
|
|
|
December 31, |
|
|
December 31, |
|
|
|
|
|
|
|
|
|
|
% Increase/ |
|
|
|
|
|
|
|
|
|
|
% Increase/ |
|
(Dollar amounts in millions) |
|
2006 |
|
|
2005 |
|
|
(Decrease) |
|
|
2006 |
|
|
2005 |
|
|
(Decrease) |
|
|
Net revenues |
|
$ |
541.9 |
|
|
$ |
489.7 |
|
|
|
10.7% |
|
|
$ |
1,027.3 |
|
|
$ |
911.9 |
|
|
|
12.7% |
|
Cost of sales |
|
|
239.4 |
|
|
|
222.9 |
|
|
|
7.4% |
|
|
|
463.5 |
|
|
|
418.7 |
|
|
|
10.7% |
|
|
Gross margin |
|
|
302.5 |
|
|
|
266.8 |
|
|
|
13.4% |
|
|
|
563.8 |
|
|
|
493.2 |
|
|
|
14.3% |
|
SG&A expenses |
|
|
154.9 |
|
|
|
144.6 |
|
|
|
7.1% |
|
|
|
297.2 |
|
|
|
276.5 |
|
|
|
7.5% |
|
R&D |
|
|
62.2 |
|
|
|
73.1 |
|
|
|
(14.9% |
) |
|
|
120.1 |
|
|
|
142.8 |
|
|
|
(15.9% |
) |
Amortization of purchased intangible assets |
|
|
2.9 |
|
|
|
0.7 |
|
|
|
314.3% |
|
|
|
5.6 |
|
|
|
1.7 |
|
|
|
229.4% |
|
Employee-related charges, asset
impairments and other |
|
|
2.5 |
|
|
|
0.3 |
|
|
|
733.3% |
|
|
|
6.0 |
|
|
|
1.2 |
|
|
|
400.0% |
|
Asset dispositions and legal settlements |
|
|
(10.2 |
) |
|
|
3.1 |
|
|
|
(429.0% |
) |
|
|
(1.1 |
) |
|
|
26.6 |
|
|
|
(104.1% |
) |
Acquired research and development |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
114.3 |
|
|
|
|
|
|
|
|
|
|
Operating income |
|
|
90.2 |
|
|
|
45.0 |
|
|
|
100.4% |
|
|
|
21.7 |
|
|
|
44.4 |
|
|
|
(51.1% |
) |
Gain on investments, net |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
0.2 |
|
|
|
4.5 |
|
|
|
(95.6% |
) |
Interest income, net |
|
|
10.4 |
|
|
|
9.2 |
|
|
|
13.0% |
|
|
|
19.6 |
|
|
|
18.9 |
|
|
|
3.7% |
|
Other income (expense), net |
|
|
1.0 |
|
|
|
1.0 |
|
|
|
% |
|
|
|
2.4 |
|
|
|
2.7 |
|
|
|
(11.1% |
) |
|
Income before income taxes |
|
|
101.6 |
|
|
|
55.2 |
|
|
|
84.1% |
|
|
|
43.9 |
|
|
|
70.5 |
|
|
|
(37.7% |
) |
Provision for income taxes |
|
|
27.1 |
|
|
|
41.1 |
|
|
|
(34.1% |
) |
|
|
35.4 |
|
|
|
31.2 |
|
|
|
13.5% |
|
|
Net income |
|
$ |
74.5 |
|
|
$ |
14.1 |
|
|
|
428.4% |
|
|
$ |
8.5 |
|
|
$ |
39.3 |
|
|
|
(78.4% |
) |
|
Percentage of net revenues: |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Gross margin |
|
|
55.8% |
|
|
|
54.5% |
|
|
|
|
|
|
|
54.9% |
|
|
|
54.1% |
|
|
|
|
|
SG&A expenses |
|
|
28.6% |
|
|
|
29.5% |
|
|
|
|
|
|
|
28.9% |
|
|
|
30.3% |
|
|
|
|
|
R&D |
|
|
11.5% |
|
|
|
14.9% |
|
|
|
|
|
|
|
11.7% |
|
|
|
15.7% |
|
|
|
|
|
Operating income |
|
|
16.6% |
|
|
|
9.2% |
|
|
|
|
|
|
|
2.1% |
|
|
|
4.9% |
|
|
|
|
|
|
Effective income tax rate |
|
|
27% |
|
|
|
74% |
|
|
|
|
|
|
|
81% |
|
|
|
44% |
|
|
|
|
|
|
The following table summarizes the impact of the previously described events impacting
comparability included in the financial results for fiscal 2007 and 2006:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Three Months Ended |
|
|
Six Months Ended |
|
|
|
December 31, |
|
|
December 31, |
(Dollar amounts in millions) |
|
2006 |
|
|
2005 |
|
|
2006 |
|
|
2005 |
|
|
Income (charge) included in income
before income taxes |
|
|
$ 10.2 |
|
|
|
$ (3.4 |
) |
|
$ |
(116.7 |
) |
|
$ |
(23.3 |
) |
Provision (benefit) for income taxes |
|
|
2.3 |
|
|
|
26.5 |
|
|
|
(10.4 |
) |
|
|
7.8 |
|
|
Net income increased in the second quarter of fiscal 2007 compared to the prior year quarter
primarily due to the previously described events impacting comparability, higher net revenues, and
lower R&D expenses, partially offset by higher SG&A expenses. Net income decreased in the first
six months of fiscal 2007 compared to prior year period primarily due to the previously described
events impacting comparability and higher SG&A expenses, partially offset by higher net revenues
and lower R&D expenses. The net effect of foreign currency on our net income was a benefit of
approximately $6 million during the second quarter of fiscal 2007 and approximately $9 million
during the first six months of fiscal 2007 as compared to the prior year periods. Read our
discussion of segments for information on their financial results.
Net revenues, which include the favorable effects of foreign currency, increased in the second
quarter and first six months of fiscal 2007 compared with the prior year periods. Revenues
included a favorable impact of approximately 3% for the second
quarter and first six months of fiscal 2007 related to the acquisition of the Research Products Division of Ambion,
34
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
Inc., which was
effective March 1, 2006. The effect of foreign currency increased net revenues by approximately 2%
for the second quarter and first six months of fiscal 2007 as compared to the prior year periods.
|
|
Net revenues increased at the Applied Biosystems group, driven by
strength in the Real-Time PCR/Applied Genomics product category,
primarily due to higher sales of consumables products, and in the
Mass Spectrometry product category, led by sales of Q TRAP®
and QSTAR® systems and increased instrument
service contract revenue. Partially offsetting this growth in the
second quarter of fiscal 2007 were lower sales of the API triple
quadrupole, or quad, system compared to the prior year quarter.
Higher sales of DNA sequencing consumables and increased
instrument service contract revenue contributed to the growth in
the DNA Sequencing product category. |
|
|
Net revenues increased at the Celera group, primarily due to
revenue from the sale of a small molecule program and licensing
revenues related to the previously disclosed settlement with
Beckman Coulter. Equalization payments from Abbott Laboratories
were lower in the second quarter of fiscal 2007 and higher in the
first six months of fiscal 2007 compared to the prior year
periods. |
The effect of foreign currency increased revenues by approximately 5% in Europe and by
approximately 2% in Asia Pacific during the second quarter of fiscal 2007 as compared to the prior
year quarter. Excluding the effects of foreign currency, revenues increased by approximately 8% in
Europe. In the U.S., revenues increased by approximately 5%. Revenues in Japan, which are
included in total revenues for Asia Pacific, increased approximately 6% as compared to the prior
year quarter, including favorable foreign currency effects of approximately 2%. Revenues in other
Asia Pacific countries increased by approximately 29% as compared to the prior year quarter.
The effect of foreign currency increased revenues by approximately 4% in Europe during the first
six months of fiscal 2007 as compared to the prior year period. Excluding the effects of foreign
currency, revenues increased by approximately 10% in Europe. In the U.S., revenues increased by
approximately 7%. Revenues in Japan, which are included in total revenues for Asia Pacific,
increased approximately 7% as compared to the prior year period. Revenues in other Asia Pacific
countries increased by approximately 32% as compared to the prior year period.
The higher gross margin percentage for the second quarter of fiscal 2007 as compared to the prior
year quarter was due primarily to the favorable effects of foreign currency, lower royalty costs,
and improved service margins, all at the Applied Biosystems group, and higher revenues at the
Celera group, partially
offset by competitive pricing and higher inventory-related costs in the Mass Spectrometry product
category at the Applied Biosystems group. The gross margin percentage increased for the first six
months of fiscal 2007 over the prior year period due primarily to the favorable effects of foreign
currency and improved service margins, all at the Applied Biosystems group, and higher revenues at
the Celera group, partially offset by increased royalty costs at the Applied Biosystems group as a
result of recent legal settlements. The improvement in service margins at the Applied Biosystems
group was primarily driven by improved efficiency of the field service organization and growth in
the volume of service contracts.
SG&A expenses for the second quarter of fiscal 2007 increased compared to the prior year quarter
due primarily to operating and integration costs of approximately $10 million related to our
acquired businesses, increased employee-related costs, including sales commissions, of
approximately $5 million, and strategic investments of approximately $3 million to support growth
in China, Europe and North America, all at the Applied Biosystems group. This increase was
partially offset by lower legal expenses of approximately $4 million at the Applied Biosystems
group.
SG&A expenses for the first six months of fiscal 2007 increased compared to the prior year period
due primarily to operating and integration costs of approximately $18 million related to our
acquired businesses, higher employee-related costs, including sales commissions, of approximately
$14 million, and strategic investments of approximately $5 million to support growth in China,
Europe and North America, all at the Applied Biosystems group. This increase was partially offset
by lower legal expenses of approximately $13 million, including a reversal of a $5 million accrual
related to settled litigation.
R&D expenses decreased for both the second quarter and first six months of fiscal 2007 compared to
the prior year periods primarily as a result of the Celera groups decision to exit small molecule
drug discovery and development as well as costs incurred in fiscal 2006 for R&D projects at the
Applied Biosystems group, both of which were partially offset by
35
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
increased costs related to our
acquired businesses and for the U.S. Department of Defense contract awarded to the Applied
Biosystems group in August 2006.
Interest income, net increased during the second quarter and first six months of fiscal 2007
compared to the same periods last year primarily due to higher average interest rates, partially
offset by lower average cash and cash equivalents and short-term investments. The lower cash and
cash equivalents and short-term investments were primarily the result of share repurchases in both
fiscal 2007 and 2006, the acquisition of Ambion in March 2006, and the acquisition of APG in July
2006.
The effective tax rate decreased in the second quarter of fiscal 2007 compared to the second
quarter of fiscal 2006 primarily due to the previously described events impacting comparability
and, in particular, the tax charge at the Applied Biosystems group in the second quarter of fiscal
2006 relating to the repatriation, under the American Jobs Creation Act, of cash balances held
outside the U.S. In addition, the effective tax rate for the second quarter of fiscal 2007
benefited from the extension of the R&D tax credit as a result of the Tax Relief and Health Care
Act of 2006.
The effective tax rate increased in the first half of fiscal 2007 compared to the same period last
year. This increase was primarily due to the previously described events impacting comparability.
In particular, the charge for acquired IPR&D at the Applied Biosystems group in the first quarter
of fiscal 2007 did not generate any tax benefit, while a tax benefit resulted from the resolution
of transfer pricing matters in Japan at the Applied Biosystems group in the first quarter of fiscal
2006. Partially offsetting this increase was the tax charge at the Applied Biosystems group in the
second quarter of fiscal 2006 relating to the repatriation as well as the benefit from the
extension of the R&D tax credit in the second quarter of fiscal 2007.
Applera Corporation
Discussion of Condensed Consolidated Financial Resources and Liquidity
We had cash and cash equivalents and short-term investments of $910.6 million at December 31, 2006,
and $943.4 million at June 30, 2006. We maintain a $200 million unsecured revolving credit
agreement with four banks that matures on April 15, 2010, under which there were no borrowings
outstanding at December
31, 2006. Cash provided by operating activities has been our primary source of funds over the last
fiscal year.
We believe that existing funds, cash generated from operations, and existing sources of debt
financing are more than adequate to satisfy our normal operating cash flow needs, planned capital
expenditures, acquisitions, share repurchases, and dividends for the next twelve months and for the
foreseeable future.
In the second quarter of fiscal 2007, we repurchased approximately 1.6 million shares of
Applera-Applied Biosystems stock under the existing authorization from our board of directors to
replenish shares issued under our employee stock benefit plans. This authorization has no set
dollar or time limits and delegates to our management discretion to purchase shares at times and
prices it deems appropriate through open market purchases, privately negotiated transactions,
tender offers, exchange offers, or otherwise. In July 2005, we announced that our board of
directors authorized the repurchase of up to 10% of the outstanding shares of Applera-Applied
Biosystems stock. In addition, in January 2006, we announced that our board of directors
authorized the repurchase of up to an additional 5 million shares of Applera-Applied Biosystems
stock. We completed both of these repurchase authorizations in fiscal 2006.
|
|
|
|
|
|
|
|
|
|
|
December 31, |
|
|
June 30, |
|
(Dollar amounts in millions) |
|
2006 |
|
|
2006 |
|
|
Cash and cash equivalents |
|
$ |
319.3 |
|
|
$ |
434.2 |
|
Short-term investments |
|
|
591.3 |
|
|
|
509.2 |
|
|
Total cash and cash equivalents and
short-term investments |
|
$ |
910.6 |
|
|
$ |
943.4 |
|
Working capital |
|
|
1,083.3 |
|
|
|
1,018.7 |
|
|
36
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
Cash and cash equivalents decreased for the first six months of fiscal 2007 from June 30, 2006, as
cash expenditures for the acquisition of APG, share repurchases, the purchase of capital and other
assets, net of sales and maturities, and the payment of dividends, exceeded cash generated from
operating activities and proceeds from stock issuances.
Net cash flows from continuing operations for the six months ended December 31 were as follows:
|
|
|
|
|
|
|
|
|
(Dollar amounts in millions) |
|
2006 |
|
|
2005 |
|
|
Net cash from operating activities |
|
$ |
108.6 |
|
|
$ |
124.7 |
|
Net cash from investing activities |
|
|
(229.0 |
) |
|
|
30.5 |
|
Net cash from financing activities |
|
|
(0.7 |
) |
|
|
(394.9 |
) |
Effect of exchange rate changes on cash |
|
|
6.2 |
|
|
|
(8.7 |
) |
|
Operating activities:
The decrease in net cash provided from operating activities for the first six months of fiscal 2007
compared to the first six months of fiscal 2006 resulted primarily from a higher use of cash in
accounts payable and other liabilities and accounts receivable in fiscal 2007, partially offset by
higher income-related cash flows. Fiscal 2007 included proceeds of $11.7 million at the Celera
group primarily from the sale of a small molecule drug discovery and development program, increased
licensing revenues, and the legal settlement related to the Online/Information Business. The
higher use of cash in accounts payable and other liabilities primarily resulted from the timing of
vendor and income tax payments, lower income tax accruals in fiscal 2007 due to the repatriation in
fiscal 2006, and higher compensation-related payments in fiscal 2007, partially offset by lower
severance and excess lease space payments in fiscal 2007, all at the Applied Biosystems group. The
higher use of cash in accounts receivables at the Applied Biosystems
group was due to increased
sales, including sales of Ambion products. Within prepaid expenses and other assets, the timing of the receipts of
dividends and distributions related to joint venture activities was offset by the collection of
non-trade receivables also related to joint venture activities in fiscal 2007. The Applied
Biosystems groups days sales outstanding was 55 days at December 31, 2006, compared to 54 days at
June 30, 2006 and 53 days at December 31, 2005.
Investing activities:
The first six months of fiscal 2007 included higher purchases, net of sales and maturities, of
available for sale investments. In July 2006, we acquired APG for approximately $121 million,
including transaction costs, as described in Note 3 to our condensed consolidated financial
statements. The first six months of fiscal 2006 included proceeds received from the sale of a
non-strategic investment.
Financing activities:
The first six months of fiscal 2007 included two dividend payments on Applera-Applied Biosystems
stock compared to one dividend payment in the first six months of fiscal 2006. Dividends were
declared but not paid in the second quarter of fiscal 2006. During the first six months of fiscal
2007, we repurchased approximately 1.6 million shares of Applera-Applied Biosystems stock for $59.9
million. During the first six months of fiscal 2006, we repurchased approximately 19.5 million
shares of Applera-Applied Biosystems stock for $457.1 million.
37
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
Contractual Obligations
Our significant contractual obligations at December 31, 2006, and the anticipated payments under
these obligations were as follows:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Payments by Period |
|
|
|
|
|
|
|
|
|
|
|
2008 - |
|
|
2010 - |
|
|
|
|
(Dollar amounts in millions) |
|
Total |
|
|
2007 (a) |
|
|
2009 |
|
|
2011 |
|
|
Thereafter |
|
|
Minimum operating lease payments
(b) |
|
$ |
132.4 |
|
|
$ |
19.5 |
|
|
$ |
56.8 |
|
|
$ |
30.8 |
|
|
$ |
25.3 |
|
Purchase obligations (c) |
|
|
162.3 |
|
|
|
87.0 |
|
|
|
56.8 |
|
|
|
18.5 |
|
|
|
- |
|
Other long-term liabilities (d) |
|
|
38.6 |
|
|
|
2.2 |
|
|
|
2.2 |
|
|
|
1.5 |
|
|
|
32.7 |
|
|
Total |
|
$ |
333.3 |
|
|
$ |
108.7 |
|
|
$ |
115.8 |
|
|
$ |
50.8 |
|
|
$ |
58.0 |
|
|
|
|
|
(a) |
|
Represents cash obligations for the remainder of fiscal 2007. |
|
(b) |
|
Refer to Note 10 to our consolidated financial statements in our 2006 Annual Report
to Stockholders for further information. |
|
(c) |
|
Purchase obligations are entered into with various vendors in the normal course of
business, and include commitments related to capital expenditures, R&D arrangements and
collaborations, license agreements, and other services. |
|
(d) |
|
We have excluded deferred revenues as they have no impact on our future liquidity.
We have also excluded deferred tax liabilities and obligations connected with our pension and
postretirement plans and other foreign employee-related plans as they are not contractually fixed
as to timing and amount. See Note 11 to our condensed consolidated financial statements contained
in this report and Note 5 to our consolidated financial statements in our 2006 Annual Report to
Stockholders for more information on these plans. |
38
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
Discussion of Segments Operations, Financial Resources and Liquidity
Applied Biosystems Group
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Three Months Ended |
|
|
Six Months Ended |
|
|
|
December 31, |
|
|
December 31, |
|
|
|
|
|
|
|
|
|
|
% Increase/ |
|
|
|
|
|
|
|
|
|
|
% Increase/ |
|
(Dollar amounts in millions) |
|
2006 |
|
|
2005 |
|
|
(Decrease) |
|
|
2006 |
|
|
2005 |
|
|
(Decrease) |
|
|
Net revenues |
|
$ |
530.0 |
|
|
$ |
481.9 |
|
|
|
10.0% |
|
|
$ |
1,006.3 |
|
|
$ |
897.4 |
|
|
|
12.1% |
|
Cost of sales |
|
|
235.5 |
|
|
|
219.4 |
|
|
|
7.3% |
|
|
|
456.2 |
|
|
|
412.7 |
|
|
|
10.5% |
|
|
Gross margin |
|
|
294.5 |
|
|
|
262.5 |
|
|
|
12.2% |
|
|
|
550.1 |
|
|
|
484.7 |
|
|
|
13.5% |
|
SG&A expenses |
|
|
147.5 |
|
|
|
135.8 |
|
|
|
8.6% |
|
|
|
282.6 |
|
|
|
257.8 |
|
|
|
9.6% |
|
R&D |
|
|
50.9 |
|
|
|
45.2 |
|
|
|
12.6% |
|
|
|
96.0 |
|
|
|
86.1 |
|
|
|
11.5% |
|
Amortization
of purchased
intangible assets |
|
|
2.9 |
|
|
|
0.3 |
|
|
|
866.7% |
|
|
|
5.6 |
|
|
|
0.6 |
|
|
|
833.3% |
|
Employee-related charges, asset
impairments and other |
|
|
|
|
|
|
0.3 |
|
|
|
(100.0% |
) |
|
|
|
|
|
|
1.2 |
|
|
|
(100.0% |
) |
Asset dispositions and legal
settlements |
|
|
(7.8 |
) |
|
|
3.1 |
|
|
|
(351.6% |
) |
|
|
1.3 |
|
|
|
25.9 |
|
|
|
(95.0% |
) |
Acquired research and
development |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
114.3 |
|
|
|
|
|
|
|
|
|
|
Operating income |
|
|
101.0 |
|
|
|
77.8 |
|
|
|
29.8% |
|
|
|
50.3 |
|
|
|
113.1 |
|
|
|
(55.5% |
) |
Gain on investments, net |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
0.2 |
|
|
|
|
|
|
|
|
|
Interest income, net |
|
|
3.4 |
|
|
|
3.3 |
|
|
|
3.0% |
|
|
|
6.0 |
|
|
|
7.7 |
|
|
|
(22.1% |
) |
Other income (expense), net |
|
|
0.9 |
|
|
|
1.2 |
|
|
|
(25.0% |
) |
|
|
2.2 |
|
|
|
2.9 |
|
|
|
(24.1% |
) |
|
Income before income taxes |
|
|
105.3 |
|
|
|
82.3 |
|
|
|
27.9% |
|
|
|
58.7 |
|
|
|
123.7 |
|
|
|
(52.5% |
) |
Provision for income taxes |
|
|
30.5 |
|
|
|
51.4 |
|
|
|
(40.7% |
) |
|
|
42.6 |
|
|
|
49.7 |
|
|
|
(14.3% |
) |
|
Net income |
|
$ |
74.8 |
|
|
$ |
30.9 |
|
|
|
142.1% |
|
|
$ |
16.1 |
|
|
$ |
74.0 |
|
|
|
(78.2% |
) |
|
Percentage of net revenues: |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Gross margin |
|
|
55.6% |
|
|
|
54.5% |
|
|
|
|
|
|
|
54.7% |
|
|
|
54.0% |
|
|
|
|
|
SG&A expenses |
|
|
27.8% |
|
|
|
28.2% |
|
|
|
|
|
|
|
28.1% |
|
|
|
28.7% |
|
|
|
|
|
R&D |
|
|
9.6% |
|
|
|
9.4% |
|
|
|
|
|
|
|
9.5% |
|
|
|
9.6% |
|
|
|
|
|
Operating income |
|
|
19.1% |
|
|
|
16.1% |
|
|
|
|
|
|
|
5.0% |
|
|
|
12.6% |
|
|
|
|
|
|
Effective income tax rate |
|
|
29% |
|
|
|
62% |
|
|
|
|
|
|
|
73% |
|
|
|
40% |
|
|
|
|
|
|
The following table summarizes the impact of the previously described events impacting
comparability included in the financial results for fiscal 2007 and 2006:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Three Months Ended |
|
|
Six Months Ended |
|
|
|
December 31, |
|
|
December 31, |
(Dollar amounts in millions) |
|
2006 |
|
|
2005 |
|
|
2006 |
|
|
2005 |
|
|
Income (charge) included in income
before income taxes |
|
$ |
7.8 |
|
|
$ |
(3.4 |
) |
|
$ |
(115.6 |
) |
|
$ |
(27.1 |
) |
Provision (benefit) for income taxes |
|
|
2.5 |
|
|
|
26.5 |
|
|
|
(9.2 |
) |
|
|
(6.0 |
) |
|
Net income increased in the second quarter of fiscal 2007 compared to the prior year quarter
primarily due to the previously described events impacting comparability and higher net revenues,
partially offset by higher operating expenses. Net income decreased in the first six months of
fiscal 2007 compared to prior year period primarily due to the previously described events
impacting comparability and higher operating expenses, partially offset by higher net revenues.
The net effect of foreign currency on our net income was a benefit of approximately $6 million
during the second quarter of fiscal 2007 and approximately $9 million during the first six months
of fiscal 2007 as compared to the prior year periods.
39
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
Revenues overall summary
The following table sets forth the Applied Biosystems groups revenues by product categories for
the three and six months ended December 31:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Three Months Ended |
|
|
Six Months Ended |
|
|
|
December 31, |
|
|
December 31, |
|
|
|
|
|
|
|
|
|
|
% Increase/ |
|
|
|
|
|
|
|
|
|
|
% Increase/ |
|
(Dollar amounts in millions) |
|
|
2006 |
|
|
|
2005 |
|
|
(Decrease) |
|
|
|
2006 |
|
|
|
2005 |
|
|
(Decrease) |
|
|
DNA Sequencing |
|
|
$146.8 |
|
|
|
$140.7 |
|
|
|
4% |
|
|
$ |
278.3 |
|
|
|
$265.6 |
|
|
|
5% |
|
% of total revenues |
|
|
28% |
|
|
|
29% |
|
|
|
|
|
|
|
28% |
|
|
|
30% |
|
|
|
|
|
|
Real-Time PCR/Applied Genomics |
|
|
172.6 |
|
|
|
146.8 |
|
|
|
18% |
|
|
|
330.7 |
|
|
|
268.5 |
|
|
|
23% |
|
% of total revenues |
|
|
32% |
|
|
|
30% |
|
|
|
|
|
|
|
33% |
|
|
|
30% |
|
|
|
|
|
|
Mass Spectrometry |
|
|
135.9 |
|
|
|
119.4 |
|
|
|
14% |
|
|
|
251.9 |
|
|
|
216.7 |
|
|
|
16% |
|
% of total revenues |
|
|
26% |
|
|
|
25% |
|
|
|
|
|
|
|
25% |
|
|
|
24% |
|
|
|
|
|
|
Core PCR & DNA Synthesis |
|
|
49.2 |
|
|
|
47.6 |
|
|
|
3% |
|
|
|
95.4 |
|
|
|
95.0 |
|
|
|
% |
|
% of total revenues |
|
|
9% |
|
|
|
10% |
|
|
|
|
|
|
|
9% |
|
|
|
10% |
|
|
|
|
|
|
Other Product Lines |
|
|
25.5 |
|
|
|
27.4 |
|
|
|
(7% |
) |
|
|
50.0 |
|
|
|
51.6 |
|
|
|
(3% |
) |
% of total revenues |
|
|
5% |
|
|
|
6% |
|
|
|
|
|
|
|
5% |
|
|
|
6% |
|
|
|
|
|
|
Total |
|
|
$530.0 |
|
|
|
$481.9 |
|
|
|
10% |
|
|
$ |
1,006.3 |
|
|
|
$897.4 |
|
|
|
12% |
|
|
Revenues for the second quarter and first six months of fiscal 2007 included a favorable impact of
approximately 3% related to the Ambion acquisition, which was effective March 1, 2006. The effect
of foreign currency increased net revenues in the second quarter and first six months of fiscal
2007 by approximately 2% as compared to the prior year periods.
|
|
Revenues in the Real-Time PCR/Applied Genomics product category
increased primarily due to higher sales of consumables products,
largely due to the acquisition of Ambion. Sales of
TaqMan® Gene Expression Assays products used in
academic, clinical research and agricultural biotechnology
settings and human identification products used in forensics also
contributed to the product category growth. Additionally,
instrument revenues increased due to higher sales of low
throughput real-time PCR instruments. Revenues for the year to
date period were also favorably impacted by increased service
revenue. In the research market, we are benefiting from a
decentralization trend where a growing number of smaller labs are
purchasing their own real-time PCR technology rather than relying
on core facilities. We are also seeing growth in quality and
safety testing applications within the applied markets, especially
in high-volume food manufacturing and environmental testing.
Consumables growth in the second quarter of fiscal 2007 benefited
from sales of DNA forensic kits in the applied markets, expansion
of our overall installed base of real-time instruments, and demand
for TaqMan assays for validation and screening
applications. Growth in the real-time product category was
affected by year-over-year comparables in our BioSecurity business
as well as from on-going competition within the real-time PCR
instruments market. |
|
|
Mass Spectrometry revenue growth for the second quarter of fiscal
2007 was led by sales of Q TRAP® and QSTAR®
systems, as well as increased instrument service contract revenue.
Partially offsetting this growth were lower sales of the API
triple quad. Our small molecule business performed well in the
second quarter of fiscal 2007 with growth across our family of Q
TRAP hybrid instruments for traditional pharmaceutical and
contract research organizations (CRO) applications, as well as
within quality and safety testing applications in the applied
markets. Our proteomics business was led by sales of our new
QSTAR Elite platform and continued demand for our 4800 MALDI
TOF/TOF system for biomarker discovery and validation workflows.
For the year to date period, revenues were led by sales of Q TRAP,
QSTAR, API triple quad, and MALDI TOF/TOF systems, as well as
increased instrument service contract revenue. |
|
|
Revenues in the DNA Sequencing product category increased due to
higher sales of DNA sequencing consumables and instrument service
contract revenue. Our performance in this area continues to
benefit from the ongoing expansion and adoption of DNA forensics,
increased demand for quality assurance applications in
pharmaceutical |
40
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
|
|
and healthcare companies, and clinical research
customers performing medical sequencing and genotyping
applications. Consumables growth was driven by the increase in
the total number of reactions performed on the Applied Biosystems
groups installed base of sequencers, primarily the result of
increased focus in applications such as re-sequencing and fragment
analysis. |
Revenue by sources
The following table sets forth the Applied Biosystems groups revenues by sources for the three and
six month periods ended December 31:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Three Months Ended |
|
|
Six Months Ended |
|
|
|
December 31, |
|
|
December 31, |
|
|
|
|
|
|
|
|
|
|
% Increase/ |
|
|
|
|
|
|
|
|
|
|
% Increase/ |
|
(Dollar amounts in millions) |
|
2006 |
|
|
2005 |
|
|
(Decrease) |
|
|
2006 |
|
|
2005 |
|
|
(Decrease) |
|
|
Instruments |
|
$ |
234.4 |
|
|
$ |
223.3 |
|
|
|
5.0% |
|
|
$ |
431.1 |
|
|
$ |
394.4 |
|
|
|
9.3% |
|
Consumables |
|
|
206.8 |
|
|
|
177.9 |
|
|
|
16.2% |
|
|
|
399.6 |
|
|
|
343.9 |
|
|
|
16.2% |
|
Other sources |
|
|
88.8 |
|
|
|
80.7 |
|
|
|
10.0% |
|
|
|
175.6 |
|
|
|
159.1 |
|
|
|
10.4% |
|
|
Total |
|
$ |
530.0 |
|
|
$ |
481.9 |
|
|
|
10.0% |
|
|
$ |
1,006.3 |
|
|
$ |
897.4 |
|
|
|
12.1% |
|
|
Instruments
For the second quarter of fiscal 2007, instrument revenues increased from the prior year quarter
primarily due to higher sales in the Mass Spectrometry product category. This growth was driven by
higher sales of the Q TRAP and QSTAR systems. Also favorably impacting instrument revenues for the
quarter were higher sales of low throughput real-time PCR instruments for core research and applied
market applications in the Real-Time PCR/Applied Genomics category.
For the first six months of fiscal 2007, instrument revenues increased as compared to the prior
year period due primarily to higher sales in both the Mass Spectrometry and Real-Time PCR/Applied
Genomics product categories. Contributing to the increased sales in the Mass Spectrometry category
were sales of the Q TRAP, QSTAR, API triple quad, and MALDI TOF/TOF systems. The Real-Time
PCR/Applied Genomics category increased primarily as a result of higher sales of low throughput
real-time PCR instruments for core research and applied market applications.
Consumables
The increase in consumables sales in the second quarter and first six months of fiscal 2007
primarily reflected the strength of Real-Time PCR/Applied Genomics consumables sales. These sales
increased primarily as a result of the acquisition of Ambion, higher sales of TaqMan Gene
Expression Assays products, and human identification products used in forensics. Also favorably
impacting consumables revenues were higher sales of DNA sequencing consumables.
Other sources
Revenues from other sources, which included service and support, royalties, licenses, and contract
research, increased for the second quarter of fiscal 2007 due to higher service and support and
royalty and licensing revenues and increased for the first six months of fiscal 2007 primarily due
to higher service and support revenues. Additionally, favorably impacting the year to date
revenues were higher contract research revenues.
41
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
Revenues by geographic area
The following table sets forth the Applied Biosystems groups revenues by geographic area for the
three and six month periods ended December 31:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Three Months Ended |
|
|
Six Months Ended |
|
|
|
December 31, |
|
|
December 31, |
|
|
|
|
|
|
|
|
|
|
% Increase/ |
|
|
|
|
|
|
|
|
|
|
% Increase/ |
|
(Dollar amounts in millions) |
|
2006 |
|
|
2005 |
|
|
(Decrease) |
|
|
2006 |
|
|
2005 |
|
|
(Decrease) |
|
|
United States |
|
$ |
216.3 |
|
|
$ |
206.6 |
|
|
|
4.7% |
|
|
$ |
435.0 |
|
|
$ |
406.3 |
|
|
|
7.1% |
|
Europe |
|
|
196.1 |
|
|
|
173.1 |
|
|
|
13.3% |
|
|
|
345.4 |
|
|
|
301.7 |
|
|
|
14.5% |
|
Asia Pacific |
|
|
95.9 |
|
|
|
83.0 |
|
|
|
15.5% |
|
|
|
182.5 |
|
|
|
155.7 |
|
|
|
17.2% |
|
Latin America and other markets |
|
|
21.7 |
|
|
|
19.2 |
|
|
|
13.0% |
|
|
|
43.4 |
|
|
|
33.7 |
|
|
|
28.8% |
|
|
Total |
|
$ |
530.0 |
|
|
$ |
481.9 |
|
|
|
10.0% |
|
|
$ |
1,006.3 |
|
|
$ |
897.4 |
|
|
|
12.1% |
|
|
The effect of foreign currency increased revenues by approximately 5% in Europe and by
approximately 2% in Asia Pacific during the second quarter of fiscal 2007 as compared to the prior
year quarter. Excluding the effects of foreign currency, revenues increased by approximately 8% in
Europe primarily as a result of sales of Q TRAP systems, low to medium throughput genetic
analyzers, Ambion products, DNA sequencing consumables, and TaqMan Gene Expression
Assays products. Sales in the U.S. increased primarily due to sales of Ambion products, DNA
Sequencing consumables, Q TRAP systems, and chromatography media. This growth was partially offset
by lower sales of high throughput genetic analyzers and API triple quad systems. During the second
quarter of fiscal 2007, revenues in Japan, which are included in total revenues for Asia Pacific,
increased approximately 6% as compared to the prior year quarter due primarily to higher sales of
Ambion products, low to medium throughput genetic analyzers, QSTAR systems, Q TRAP systems for the
proteomics market, and favorable foreign currency effects of approximately 2%, which were partially
offset by lower sales of both low and high throughput real-time PCR instruments. Revenues in other
Asia Pacific countries increased by approximately 29% as compared to the prior year quarter. This
increase was primarily due to sales of low throughput real-time PCR instruments, QSTAR systems, and
Q TRAP systems.
The effect of foreign currency increased revenues by approximately 4% in Europe during the first
six months of fiscal 2007 as compared to the prior year period. Excluding the effects of foreign
currency, revenues increased by approximately 10% in Europe, primarily as a result of sales of low
to medium throughput genetic analyzers, Ambion products, API triple quad systems, Q TRAP systems,
TaqMan Gene Expression Assays products, and DNA Sequencing consumables. Sales in the U.S.
increased primarily due to sales of Ambion products, Q TRAP systems, human identification products,
TaqMan Gene Expression Assays products, and real-time PCR consumables. This growth was partially
offset by lower sales of API triple quad systems. During the first six months of fiscal 2007,
revenues in Japan increased approximately 7% as compared to the prior year period, primarily due to
higher sales of Ambion products, Q TRAP systems, and API triple quad systems for the small molecule
market. These sales were partially offset by lower sales of both low and high throughput real-time
PCR instruments and MALDI TOF/TOF systems. During the first six months of fiscal 2007, revenues in
other Asia Pacific countries increased by approximately 32% as compared to the prior year period
primarily due to higher sales of low throughput real-time PCR instruments, Q TRAP systems, API
triple quad systems, and DNA Sequencing consumables.
Gross margin, as a percentage of net revenues, increased for the second quarter of fiscal 2007
compared to the prior year quarter due primarily to the favorable effects of foreign currency,
lower royalty costs, and improved service margins, partially offset by competitive pricing and
higher inventory-related costs in the Mass Spectrometry product category. Gross margin, as a
percentage of net revenues, increased for the first six months of fiscal 2007 over the prior year
period due primarily to the favorable effects of foreign currency and improved service margins,
partially offset by increased royalty costs as a result of recent legal settlements. The
improvement in service margins was primarily driven by improved efficiency in the field service
organization and growth in the volume of service contracts.
SG&A expenses for the second quarter of fiscal 2007 increased compared to the prior year quarter
due primarily to operating and integration costs of approximately $10 million related to our
acquired businesses, higher employee-related costs, including sales commissions, of approximately
$5 million, and strategic investments of approximately $3 million to
42
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
support growth in China,
Europe and North America. This increase was partially offset by lower legal expenses of
approximately $4 million.
SG&A expenses for the first six months of fiscal 2007 increased compared to the prior year period
due primarily to operating and integration costs of approximately $18 million related to our
acquired businesses, higher employee-related costs, including sales commissions, of approximately
$14 million, and strategic investments of approximately $5 million to support growth in China,
Europe and North America. This increase was partially offset by lower legal expenses of
approximately $13 million, including a reversal of a $5 million accrual related to settled
litigation.
R&D expenses increased in both the second quarter and first six months of fiscal 2007 from the
prior year periods primarily as a result of costs related to our acquired businesses and for the
U.S. Department of Defense contract awarded to the Applied Biosystems group in August 2006, both of
which were partially offset by costs incurred in fiscal 2006 for R&D projects.
Interest income, net slightly increased during the second quarter of fiscal 2007 compared to the
second quarter of fiscal 2006 due to higher average interest rates offset by lower average cash and
cash equivalents and short-term investments. Interest income, net decreased during the first six
months of fiscal 2007 as compared to the prior year period primarily due to lower average cash and
cash equivalents and short-term investments, partially offset by higher average interest rates.
The lower cash and cash equivalents and short-term investments were primarily the result of share
repurchases in both fiscal 2007 and 2006, the acquisition of Ambion in March 2006, and the
acquisition of APG in July 2006.
The effective tax rate decreased in the second quarter of fiscal 2007 compared to the second
quarter of fiscal 2006 primarily due to the previously described events impacting comparability
and, in particular, the tax charge in the second quarter of fiscal 2006 relating to the
repatriation, under the American Jobs Creation Act, of cash balances held outside the U.S. In
addition, the effective tax rate for the second quarter of fiscal 2007 benefited from the extension
of the R&D tax credit as a result of the Tax Relief and Health Care Act of 2006.
The effective tax rate increased in the first half of fiscal 2007 compared to the same period last
year. This increase was primarily due to the previously described events impacting comparability.
In particular, the charge for acquired IPR&D in the first quarter of fiscal 2007 did not generate
any tax benefit, while a tax benefit resulted from the resolution of transfer pricing matters in
Japan in the first quarter of fiscal 2006. Partially offsetting this increase was the tax charge
in the second quarter of fiscal 2006 relating to the repatriation as well as the benefit from the
extension of the R&D tax credit in the second quarter of fiscal 2007.
Applied Biosystems Group
Discussion of Financial Resources and Liquidity
The Applied Biosystems group had cash and cash equivalents and short-term investments of $343.7
million at December 31, 2006, and $373.9 million at June 30, 2006. We maintain a $200 million
unsecured revolving credit agreement with four banks that matures on April 15, 2010, under which
there were no borrowings outstanding at December 31, 2006. Cash provided by operating activities
has been our primary source of funds over the last fiscal year.
We believe that existing funds, cash generated from operations, and existing sources of debt
financing are more than adequate to satisfy the Applied Biosystems groups normal operating cash
flow needs, planned capital expenditures, acquisitions, share repurchases, and dividends for the
next twelve months and for the foreseeable future.
In the second quarter of fiscal 2007, we repurchased approximately 1.6 million shares of
Applera-Applied Biosystems stock under the existing authorization from our board of directors to
replenish shares issued under our employee stock benefit plans. This authorization has no set
dollar or time limits and delegates to our management discretion to purchase shares at times and
prices it deems appropriate through open market purchases, privately negotiated transactions,
tender offers, exchange offers, or otherwise. In July 2005, we announced that our board of
directors authorized the repurchase of up to 10% of the outstanding shares of Applera-Applied
Biosystems stock. In addition, in January 2006, we announced that our board of directors
authorized the repurchase of up to 5 million shares of Applera-Applied Biosystems stock. We
completed both of these supplemental repurchase authorizations in fiscal 2006.
43
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
We manage the investment of surplus cash and the issuance and repayment of short and long-term debt
for the Applied Biosystems group and the Celera group on a centralized basis and allocate activity
within these balances to the group that uses or generates such resources.
|
|
|
|
|
|
|
|
|
|
|
December 31, |
|
|
June 30, |
|
(Dollar amounts in millions) |
|
2006 |
|
|
2006 |
|
|
Cash and cash equivalents |
|
|
$ 296.5 |
|
|
$ |
373.9 |
|
Short-term investments |
|
|
47.2 |
|
|
|
|
|
|
Total cash and cash equivalents and
short-term investments |
|
|
$ 343.7 |
|
|
$ |
373.9 |
|
Working capital |
|
|
504.0 |
|
|
|
439.5 |
|
|
Cash and cash equivalents decreased from June 30, 2006, as cash expenditures for the acquisition of
APG, share repurchases, the purchase of capital and other assets, net of sales, and the payment of
dividends, exceeded cash generated from operating activities and proceeds from stock issuances.
Net cash flows of continuing operations for the six months ended December 31 were as follows:
|
|
|
|
|
|
|
|
|
(Dollar amounts in millions) |
|
2006 |
|
|
2005 |
|
|
Net cash from operating activities |
|
$ |
123.8 |
|
|
$ |
185.6 |
|
Net cash from investing activities |
|
|
(195.6 |
) |
|
|
(27.8 |
) |
Net cash from financing activities |
|
|
(11.8 |
) |
|
|
(406.1 |
) |
Effect of exchange rate changes on cash |
|
|
6.2 |
|
|
|
(8.7 |
) |
|
Operating activities:
Net cash from operating activities of continuing operations for the first six months of fiscal 2007
was $61.8 million lower than in the first six months of fiscal 2006. This decrease resulted
primarily from a higher use of cash in accounts payable and other liabilities and accounts
receivable in fiscal 2007, partially offset by higher income-related cash flows. The higher use of
cash in accounts payable and other liabilities primarily resulted from the timing of vendor and
income tax payments, lower income tax accruals in fiscal 2007 due to the repatriation in fiscal
2006, and higher compensation-related payments in fiscal 2007, partially offset by lower severance
and excess lease space payments in fiscal 2007. The higher use of cash in accounts receivables was
due to increased sales, including sales of Ambion products. Within prepaid expenses and other assets, the timing of
the receipts of dividends and distributions related to joint venture activities was offset by the
collection of non-trade receivables also related to joint venture activities in fiscal 2007. The
Applied Biosystems groups days sales outstanding was 55 days at December 31, 2006, compared to 54
days at June 30, 2006 and 53 days at December 31, 2005. Inventory on hand was 2.9 months at
December 31, 2006, compared to 2.4 months at June 30, 2006.
Investing activities:
The first six months of fiscal 2007 included lower sales, net of purchases, of available for sale
investments. In July 2006, we acquired APG for approximately $121 million, including transaction
costs, as described in Note 3 to our condensed consolidated financial statements.
Financing activities:
The first six months of fiscal 2007 included two dividend payments on Applera-Applied Biosystems
stock compared to one dividend payment in the first six months of fiscal 2006. Dividends were
declared but not paid in the second quarter of fiscal 2006. During the first six months of fiscal
2007, we repurchased approximately 1.6 million shares of Applera-Applied Biosystems stock for $59.9
million. During the first six months of fiscal 2006, we repurchased approximately 19.5 million
shares of Applera-Applied Biosystems stock for $457.1 million.
44
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
Celera Group
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Three Months Ended |
|
|
Six Months Ended |
|
|
|
December 31, |
|
|
December 31, |
|
|
|
|
|
|
|
|
|
|
|
% Increase/ |
|
|
|
|
|
|
|
|
|
|
% Increase/ |
|
(Dollar amounts in millions) |
|
2006 |
|
|
2005 |
|
|
(Decrease) |
|
|
2006 |
|
|
2005 |
|
|
(Decrease) |
|
|
Net revenues |
|
|
$ 13.2 |
|
|
|
$ 10.3 |
|
|
|
28.2% |
|
|
|
$ 23.4 |
|
|
|
$ 19.5 |
|
|
|
20.0% |
|
Cost of sales |
|
|
4.5 |
|
|
|
5.2 |
|
|
|
(13.5% |
) |
|
|
8.3 |
|
|
|
9.6 |
|
|
|
(13.5% |
) |
|
Gross margin |
|
|
8.7 |
|
|
|
5.1 |
|
|
|
70.6% |
|
|
|
15.1 |
|
|
|
9.9 |
|
|
|
52.5% |
|
R&D |
|
|
12.0 |
|
|
|
28.7 |
|
|
|
(58.2% |
) |
|
|
25.2 |
|
|
|
58.2 |
|
|
|
(56.7% |
) |
SG&A expenses |
|
|
7.3 |
|
|
|
8.8 |
|
|
|
(17.0% |
) |
|
|
14.5 |
|
|
|
18.7 |
|
|
|
(22.5% |
) |
Amortization of purchased
intangible assets |
|
|
|
|
|
|
0.4 |
|
|
|
(100.0% |
) |
|
|
|
|
|
|
1.1 |
|
|
|
(100.0% |
) |
Employee-related charges, asset
impairments and other |
|
|
2.5 |
|
|
|
|
|
|
|
|
|
|
|
6.0 |
|
|
|
|
|
|
|
|
|
Asset dispositions and legal
settlements |
|
|
(2.4 |
) |
|
|
|
|
|
|
|
|
|
|
(2.4 |
) |
|
|
0.7 |
|
|
|
(442.9% |
) |
|
Operating loss |
|
|
(10.7 |
) |
|
|
(32.8 |
) |
|
|
(67.4% |
) |
|
|
(28.2 |
) |
|
|
(68.8 |
) |
|
|
(59.0% |
) |
Gain on investments, net |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
4.5 |
|
|
|
(100.0% |
) |
Interest income, net |
|
|
7.0 |
|
|
|
5.9 |
|
|
|
18.6% |
|
|
|
13.5 |
|
|
|
11.2 |
|
|
|
20.5% |
|
Other income (expense), net |
|
|
0.1 |
|
|
|
(0.2 |
) |
|
|
(150.0% |
) |
|
|
0.2 |
|
|
|
(0.2 |
) |
|
|
(200.0% |
) |
|
Loss before income taxes |
|
|
(3.6 |
) |
|
|
(27.1 |
) |
|
|
(86.7% |
) |
|
|
(14.5 |
) |
|
|
(53.3 |
) |
|
|
(72.8% |
) |
Benefit for income taxes |
|
|
3.1 |
|
|
|
9.8 |
|
|
|
(68.4% |
) |
|
|
7.0 |
|
|
|
19.2 |
|
|
|
(63.5% |
) |
|
Net loss |
|
|
$ (0.5 |
) |
|
|
$(17.3 |
) |
|
|
(97.1% |
) |
|
|
$ (7.5 |
) |
|
|
$(34.1 |
) |
|
|
(78.0% |
) |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Effective income tax benefit rate |
|
|
86% |
|
|
|
36% |
|
|
|
|
|
|
|
48% |
|
|
|
36% |
|
|
|
|
|
|
The following table summarizes the impact of the previously described events impacting
comparability included in the financial results for fiscal 2007 and 2006:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Three Months Ended |
|
|
Six Months Ended |
|
|
|
December 31, |
|
|
December 31, |
|
(Dollar amounts in millions) |
|
2006 |
|
|
2005 |
|
|
2006 |
|
|
2005 |
|
|
Income (charge) included in loss
before income taxes |
|
$ |
2.4 |
|
|
$ |
|
|
|
$ |
(1.1 |
) |
|
$ |
3.8 |
|
Provision (benefit) for income taxes |
|
|
(0.3 |
) |
|
|
|
|
|
|
(1.5 |
) |
|
|
1.4 |
|
|
Effective January 1, 2006, the Celera group acquired the Applied Biosystems groups 50 percent
interest in the Celera Diagnostics joint venture such that it now owns 100 percent of Celera
Diagnostics. Prior to that date, the Celera group accounted for its interest in the Celera
Diagnostics joint venture under the equity method of accounting and included 100 percent of the
losses of Celera Diagnostics in its statement of operations as Loss from joint venture. The
Celera groups historical results have been restated for comparative purposes to reflect this
transaction. However, the acquisition did not affect the Celera groups net loss for the prior
period presented.
The lower net loss in the second quarter and first six months of fiscal 2007 compared to the prior
year periods primarily resulted from lower R&D and SG&A expenses, higher net revenues, and a higher
effective income tax benefit rate.
Reported revenues for the Celera group are comprised of product sales, equalization payments, and
license and collaborative revenues. Product sales consist primarily of shipments to our partner,
Abbott Laboratories, at cost. Revenue from items that are outside of the alliance with Abbott is
also reported in this category. Equalization payments result from an equal sharing of alliance
profits and losses between the alliance partners and vary each period depending on the relative
income and expense contribution of each partner.
Reported revenues increased for the second quarter of fiscal 2007 compared to the second
quarter of fiscal 2006 primarily due to $2.5 million of revenue from the sale of a small molecule
program and $2.0 million of licensing revenue from
45
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
Beckman Coulter, partially offset by a lower equalization payment from Abbott. The second quarter
of fiscal 2006 included $2.1 million of revenues from the discontinued Online/Information and
Paracel businesses.
Reported revenues increased for the first six months of fiscal 2007 compared to the prior year
period primarily due to $2.5 million of revenue from the sale of a small molecule program, $4.0
million of licensing revenue from Beckman Coulter, and higher equalization payments from
Abbott. The first six months of fiscal 2006 included $4.2 million of revenues from the
discontinued Online/Information and Paracel businesses.
The increase in gross margin in the second quarter and first six months of fiscal 2007 was
primarily attributable to increased licensing and collaborative revenues and the revenue from the
sale of a small molecule program, all of which had no associated cost of sales.
Both R&D and SG&A expenses decreased in the second quarter and first six months of fiscal 2007
compared to the prior year periods primarily due to the decision to exit small molecule drug
discovery and development in fiscal 2006.
Interest income, net increased during the second quarter and first six months of fiscal 2007 as
compared to the prior year periods primarily due to higher average interest rates, partially offset
by lower average cash and cash equivalents and short-term investments.
The increase in the effective income tax benefit rate for the second quarter and first six months
of fiscal 2007 compared to the prior year periods was primarily attributable to the extension of
the R&D tax credit, which included a tax benefit of $1.0 million related to the recognition of the
prior fiscal year R&D tax credit, as a result of the Tax Relief and Health Care Act of 2006.
Supplemental Information
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Three Months Ended |
|
|
Six Months Ended |
|
|
|
December 31, |
|
|
December 31, |
|
(Dollar amounts in millions) |
|
2006 |
|
|
2005 |
|
|
2006 |
|
|
2005 |
|
|
Equalization revenue, net |
|
$ |
3.5 |
|
|
$ |
4.5 |
|
|
$ |
7.9 |
|
|
$ |
7.7 |
|
End-user revenues |
|
|
23.2 |
|
|
|
19.1 |
|
|
|
49.0 |
|
|
|
36.9 |
|
|
End-user revenues included products sold through the alliance with Abbott and revenues from our
unpartnered new genetic tests. Increased sales of Human Immunodeficiency Virus (HIV) and HCV
RealTime viral load assays used on the m2000 system, sales of thrombosis ASRs, and cystic
fibrosis ASRs contributed to the year-over-year growth for both the quarter and first six months.
Also favorably impacting the six month increase were sales of the ViroSeq HIV-1
Genotyping System. The second quarter of fiscal 2006 included $1.9 million and the first six
months of fiscal 2006 included $3.6 million in end-user revenues from a low resolution human
leukocyte antigen (HLA) product line that was removed from the alliance in December 2005.
Celera Group
Discussion of Financial Resources and Liquidity
The Celera group had cash and cash equivalents and short-term investments of $566.9 million at
December 31, 2006, and $569.5 million at June 30, 2006. We maintain a $200 million unsecured
revolving credit agreement with four banks that matures on April 15, 2010, under which there were
no borrowings outstanding at December 31, 2006.
We believe that existing funds and existing sources of debt financing are more than adequate to
satisfy the Celera groups normal operating cash flow needs and planned capital expenditures for
the next twelve months and for the foreseeable future.
Our board of directors has authorized the repurchase of shares of Applera-Celera stock from time to
time to replenish shares issued under our employee stock benefit plans. This authorization has no
set dollar or time limits and delegates to
46
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
our management discretion to purchase shares at times and prices it deems appropriate through open
market purchases, privately negotiated transactions, tender offers, exchange offers, or otherwise.
We manage the investment of surplus cash and the issuance and repayment of short and long-term debt
for the Celera group and the Applied Biosystems group on a centralized basis and allocate activity
within these balances to the group that uses or generates such resources.
|
|
|
|
|
|
|
|
|
|
|
December 31, |
|
June 30, |
(Dollar amounts in millions) |
|
2006 |
|
2006 |
|
Cash and cash equivalents |
|
|
$ 22.8 |
|
|
$ |
60.3 |
|
Short-term investments |
|
|
544.1 |
|
|
|
509.2 |
|
|
Total cash and cash equivalents and
short-term investments |
|
|
$ 566.9 |
|
|
$ |
569.5 |
|
Working capital |
|
|
579.5 |
|
|
|
578.9 |
|
|
Cash and cash equivalents decreased from June 30, 2006, as the amount expended on operations, the
purchase of capital assets, and the purchases of available for sale investments, net of sales and
maturities, exceeded proceeds from stock issuances. Net cash flows for the six months ended
December 31 were as follows:
|
|
|
|
|
|
|
|
|
(Dollar amounts in millions) |
|
2006 |
|
|
2005 |
|
|
Net cash from operating activities |
|
$ |
(15.1 |
) |
|
$ |
(60.9 |
) |
Net cash from investing activities |
|
|
(33.4 |
) |
|
|
58.2 |
|
Net cash from financing activities |
|
|
11.1 |
|
|
|
11.1 |
|
|
Operating activities:
Net cash used by operating activities for the first six months of fiscal 2007 was $45.8 million
lower than the first six months of fiscal 2006. The lower use of cash resulted primarily from
lower net cash operating losses and lower working capital requirements in fiscal 2007. Fiscal 2007
included proceeds of $11.7 million primarily from the sale of a small molecule drug discovery and
development program, licensing revenue from Beckman Coulter, and the legal settlement related to
the Online/Information Business. Fiscal 2007 included approximately $2 million of higher severance
and excess lease space payments than fiscal 2006. Working capital benefited primarily from higher
proceeds from accounts receivable and a lower decrease in accounts payable and other liabilities in
fiscal 2007. The lower decrease in accounts payable and other liabilities was primarily due to the
decisions to exit small molecule drug discovery and development in fiscal 2006 and discontinue the
Online/Information business in fiscal 2005. The higher proceeds in accounts receivable was
primarily due to the collection of receivables in fiscal 2007 related to the sale of some small
molecule drug discovery and development programs.
Investing activities:
Net cash from investing activities for the first six months of fiscal 2007 decreased compared to
the first six months of fiscal 2006 due primarily to higher purchases, net of sales and maturities,
of available for sale investments in the first six months of fiscal 2007 and proceeds received on
the sale of a non-strategic investment in fiscal 2006.
47
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
Market Risks
Our foreign currency risk management strategy uses derivative instruments to hedge various foreign
currency forecasted revenues and intercompany transactions and to offset the impact of changes in
currency rates on various foreign currency-denominated assets and liabilities. The principal
objective of this strategy is to minimize the risks and/or costs associated with our global
financing and operating activities. We use forward, option, and range forward contracts to manage
our foreign currency exposures. At December 31, 2006, we recorded in our condensed consolidated
financial statements a net asset of $0.9 million related to these forward and option contracts,
compared with a net liability of $0.2 million at June 30, 2006. This increase was primarily
attributed to the fluctuations in currency rates. We do not use derivative financial instruments
for trading or speculative purposes, nor are we a party to leveraged derivatives.
We performed a sensitivity analysis as of December 31, 2006. Assuming a hypothetical 10% adverse
change in currency rates relative to the U.S. dollar as of December 31, 2006, we calculated a
hypothetical after-tax loss of $22.5 million, as compared to a hypothetical after-tax loss of $12.3
million at June 30, 2006. Our analysis included the change in the value of the derivative financial
instruments, along with the impact of translation on foreign currency-denominated assets and
liabilities. However, our analysis excluded the impact of translation of foreign currency
forecasted revenues and intercompany transactions. If currency rates actually change in a manner
similar to the assumed change in the foregoing calculation, the hypothetical calculated loss would
be more than offset by the recognition of higher U.S. dollar equivalent foreign revenues. Actual
gains and losses in the future could, however, differ materially from this analysis, based on
changes in the timing and amount of currency rate movements and actual exposures and hedges.
For further information on our market risks, refer to the discussion contained in the managements
discussion and analysis section of our 2006 Annual Report to Stockholders (which discussion is
incorporated in this quarterly report by reference).
Recently Issued Accounting Pronouncements
See Note 1 to our condensed consolidated financial statements for a description of the effect of
recently issued accounting pronouncements.
Outlook
The outlook below for the Applied Biosystems group contains non-GAAP financial measures, both
historical and forward-looking, and including earnings per share and operating margin adjusted to
exclude some costs, expenses, gains and losses and other specified items. These measures are not
in accordance with, or an alternative for, generally accepted accounting principles, or GAAP, and
may be different from non-GAAP financial measures used by other companies. Among the items
included in GAAP earnings but excluded for purposes of determining adjusted earnings or other
non-GAAP financial measures that we present are: gains or losses from sales of operating assets and
investments; restructuring charges, including severance charges; charges and recoveries relating to
significant legal proceedings; asset impairment charges; write-offs of acquired in-process research
and development; amortization of acquired intangibles; and tax adjustments, including settlements
and the impact of new tax legislation. In addition, for non-GAAP financial measures, we have also
excluded the allocation of interperiod taxes and intercompany sales. We believe the presentation
of non-GAAP financial measures provides useful information to management and investors regarding
various financial and business trends relating to our financial condition and results of
operations, and that when GAAP financial measures are viewed in conjunction with non-GAAP financial
measures, investors are provided with a more meaningful understanding of our ongoing operating
performance. In addition, these non-GAAP financial measures are among the primary indicators we
use as a basis for evaluating performance, allocating resources, setting incentive compensation
targets, and planning and forecasting future periods. Non-GAAP financial measures are not intended
to be considered in isolation or as a substitute for GAAP financial measures. To the extent this
report contains historical non-GAAP financial measures, we have also provided corresponding GAAP
financial measures for comparative purposes. However, in the case of forward-looking non-GAAP
financial measures, we have not provided corresponding forward-looking GAAP financial measures
because these measures are not accessible to us. We cannot predict the occurrence, timing, or
amount of all non-GAAP items that we exclude from our non-GAAP financial measures but which could
potentially be significant to the calculation of our GAAP financial measures for future fiscal
periods.
48
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
Applied Biosystems Group
The Applied Biosystems group believes that its fiscal year 2007 outlook and financial performance
will be affected by, among other things: the introduction and adoption of new products; the level
of commercial investments in life science R&D; the level of government funding for life science
research; the outcome of pending litigation matters; competitive product introductions and pricing;
and the continued integration of Ambion-related products.
Subject to the inherent uncertainty associated with these factors, the Applied Biosystems group has
the following expectations for fiscal 2007.
|
|
The Applied Biosystems group expects high single digit to low
double digit revenue growth for fiscal 2007 assuming current
exchange rates. This outlook includes the full fiscal year impact
from the March 2006 acquisition of Ambion. |
|
|
|
The Applied Biosystems group anticipates revenue growth in the DNA
Sequencing, Real-Time PCR/Applied Genomics, and Mass Spectrometry
product categories and revenue declines in the Core PCR and DNA
Synthesis and Other Product Lines categories. Quarterly
year-over-year revenue changes may be different from our annual
expectations due to a variety of factors, including the timing of
customer orders and disbursements of government funding. |
|
|
|
The Applied Biosystems group expects the effective annual tax rate
used to calculate non-GAAP financial measures to be approximately
30%. |
|
|
|
The Applied Biosystems group expects non-GAAP EPS to increase at a
rate equal to, or slightly above, the annual revenue growth rate.
This includes the incremental impact of the Agencourt expenses,
the incremental impact of stock based compensation, and the
increase in the effective annual tax rate from 29% in fiscal 2006.
The total impact of these three items on fiscal 2007 non-GAAP EPS
is expected to be approximately $0.10. The Applied Biosystems
group also expects that the year-over-year non-GAAP EPS growth
rate will be lower in the third quarter than in the fourth quarter
due to income from licensing fees and royalties associated with a
litigation settlement in the third quarter of fiscal 2006. |
|
|
|
The total pre-tax impact of SFAS No. 123R (accounting for stock
based compensation) in fiscal 2007 is expected to be approximately
$15 million, with an EPS impact of approximately $0.05. |
Other risks and uncertainties that may affect the Applied Biosystems groups financial performance
are detailed in the Forward-Looking Statements and Risk Factors section of this report.
Celera Group
The Celera group anticipates that its fiscal 2007 financial performance will be affected by, among
other things, continued growth in demand for current and new diagnostic products, timing of
anticipated approval of the m2000 system in the U.S., and potential revenue from technology
licenses and collaborations. End-user revenues could also be affected by Abbott Laboratories
success in obtaining a stay of the permanent injunction pertaining to HCV genotyping products
pursuant to the emergency motion described above. Subject to the inherent uncertainty associated
with these factors, the Celera group has the following expectations regarding its financial
performance for fiscal 2007:
|
|
Total reported revenues are anticipated to be $43 - $48 million,
up from the prior guidance of $40 - $45 million. This includes
revenues from licensing and collaborations, which are anticipated
to be $10 - $15 million, up from the prior guidance of $8 - $12
million. |
|
|
|
Reported R&D expenses are anticipated to be $50 - $55 million,
down from the prior guidance of $55 - $65 million. SG&A expenses
are unchanged and anticipated to be $30 - $35 million. |
|
|
|
Net loss from operations is anticipated to be $18 - $25 million,
down from the prior guidance of $28 - $35 million. |
49
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
|
|
The Celera group expects to consume approximately $10 - $20
million in cash and short-term investments, down from the prior
guidance of $35 - $45 million, to fund operations, anticipated
growth in placements of the m2000
system, and cash costs related to the fiscal 2006 restructuring. This does not include any
proceeds that might be received from the sale of the Celera groups small molecule facility in
South San Francisco, CA. |
|
|
|
Total end-user revenues recognized through the Celera groups alliance with Abbott and
total revenue from unpartnered new genetic tests are unchanged and anticipated to be $105 -
$115 million. |
Other risks and uncertainties that may affect the Celera groups financial performance are detailed
in the Forward-Looking Statements and Risk Factors section of this report.
Forward-Looking Statements and Risk Factors
Some statements contained in, or incorporated by reference in, this report, including the Outlook
section, are forward-looking and are subject to a variety of risks and uncertainties. Similarly,
the press releases we issue and other public statements we make from time to time may contain
language that is forward-looking. These forward-looking statements may be identified by the use of
forward-looking words or phrases such as forecast, believe, expect, intend, anticipate,
should, plan, estimate, and potential, among others. The forward-looking statements
contained in this report are based on our current expectations, and those made at other times will
be based on our expectations when the statements are made. We cannot guarantee that any
forward-looking statements will be realized.
The Private Securities Litigation Reform Act of 1995 provides a safe harbor for forward-looking
statements. To comply with the terms of the safe harbor, we note that a variety of factors could
cause actual results and experience to differ materially from anticipated results or other
expectations expressed in forward-looking statements. We also note that achievement of anticipated
results or expectations in forward-looking statements is subject to the possibility that
assumptions underlying forward-looking statements will prove to be inaccurate. Investors should
bear this in mind as they consider forward-looking statements. The risks and uncertainties that
may affect the operations, performance, development, and results of our Applied Biosystems group
and Celera group businesses include, but are not limited to, those described below under the
headings Risks Relating to the Applied Biosystems Group and Risks Relating to the Celera Group.
We note that our businesses could be affected by other factors that we have not disclosed because
we think they are immaterial. Also, there may be additional risks and uncertainties that could
affect our businesses but which are not currently known to us.
Owners of Applera-Applied Biosystems stock and Applera-Celera stock are also subject to risks
arising from their ownership of common stock of a corporation with two separate classes of common
stock. The risks and uncertainties that arise from our capital structure, particularly our two
separate classes of common stock, include, but are not limited to, those described in Item 1A of
Part I of our 2006 Annual Report on Form 10-K under the heading Risks Factors Risks Relating to
a Capital Structure with Two Separate Classes of Common Stock.
Risks Relating to the Applied Biosystems Group
Rapidly changing technology in life sciences could make the Applied Biosystems groups product line
obsolete unless it continues to develop and manufacture new and improved products and services, and
pursue new market opportunities. A significant portion of the net revenues for the Applied
Biosystems group each year is derived from products and services that did not exist in the prior
year. We sell our products in several industries that are characterized by rapid and significant
technological changes, frequent new product and service introductions and enhancements, and
evolving industry standards. The Applied Biosystems groups future success depends on its ability
to continually improve its current products and services, develop and introduce, on a timely and
cost-effective basis, new products and services that address the evolving needs of its customers,
and pursue new market opportunities that develop as a result of technological and scientific
advances in life sciences. These new market opportunities may be outside the scope of the Applied
Biosystems groups proven expertise or in areas which have unproven market demand, and the utility
and value of new products and services developed by the Applied Biosystems group may not be
accepted in the markets served by the new products. This includes, for example, new products under
development for the clinical diagnostics market, which are described in the immediately following
paragraph. The inability to gain market acceptance of new products and services
50
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
could harm the
Applied Biosystems groups future operating results. The Applied Biosystems groups future success
also depends on its ability to manufacture these improved and new products to meet customer demand
in a timely and cost-effective manner, including its ability to resolve in a timely manner
manufacturing issues that may arise from time to time
as the Applied Biosystems group commences production of these complex products. Unanticipated
difficulties or delays in replacing existing products and services with new products and services
or in manufacturing improved or new products in sufficient quantities to meet customer demand could
diminish future demand for the Applied Biosystems groups products and services and its future
operating results.
The Applied Biosystems group may not successfully develop instruments for use in the clinical
diagnostics market, and even if it does develop these products they may not receive needed
regulatory clearances or approvals and the Applied Biosystems group may not be able to manufacture
these products in accordance with regulatory requirements. The Applied Biosystems group intends to
commit significant resources to the development of instruments for use in the clinical diagnostics
market. Although the Applied Biosystems group has experience in developing and commercializing
instrumentation for the life science research market, the Applied Biosystems group has only limited
prior experience with products of any type for use in the regulated clinical diagnostics market.
This is an emerging business area for the Applied Biosystems group, and the Applied Biosystems
group may not have or be able to obtain the necessary expertise to successfully develop instruments
for use in this market. In addition, in the U.S. and other countries, instruments cannot be
marketed for clinical diagnostics use until they first receive regulatory clearance or approval.
The regulatory review and clearance or approval process can be time consuming and require
substantial expense and may not be successful. Even if the Applied Biosystems group obtains
regulatory clearance or approval for an instrument for use in the clinical diagnostics market, the
manufacture, sale, and distribution of that product may be subject to ongoing regulatory
requirements. The inability to comply with these requirements could cause the Applied Biosystems
group to suspend the manufacture or sale of these products and delay or prevent the Applied
Biosystems group from generating revenues from the sale of these products.
The Applied Biosystems group relies on other companies for the manufacture of some of its products
and also for the supply of some components of the products it manufactures on its own. Although
the Applied Biosystems group has contracts with most of these manufacturers and suppliers, their
operations could be disrupted. These disruptions could be caused by conditions unrelated to the
business or operations of the Applied Biosystems group, including the bankruptcy of the
manufacturer or supplier. Although the Applied Biosystems group has its own manufacturing
facilities, and generally believes it might be able to manufacture some of the products and
components currently sourced from other companies, it also believes that it could take considerable
time and resources to establish the capability to do so. Accordingly, if these other manufacturers
or suppliers are unable or fail to fulfill their obligations to the Applied Biosystems group, the
Applied Biosystems group might not be able to satisfy customer demand in a timely manner, and its
business could be harmed. For example, Delphi Medical Systems Texas Corporation, a supplier of
some instruments, parts, and components to the Applied Biosystems group under a manufacturing and
supply contract, filed a petition in the United States Bankruptcy Court on October 8, 2005, seeking
relief under the provisions of Chapter 11 of the federal Bankruptcy Code. Since the filing of the
bankruptcy petition, Delphi has continued to supply instruments, parts, and components to the
Applied Biosystems group under the contract, but Delphi informed the Applied Biosystems group that
it does not intend to continue performing under the contract after approximately May 2007. The
Applied Biosystems group intends to use its own existing manufacturing facilities to replace the
supply of some critical items that it has been purchasing from Delphi, and it is evaluating the use
of new suppliers for other critical items and is seeking to mitigate potential supply issues by
increasing inventory of some critical items. However, it is uncertain whether the Applied
Biosystems group will be able to transition the manufacture of these items to its own facilities,
hire new suppliers on acceptable terms, or increase inventories sufficiently to meet anticipated
demand, and it is also uncertain whether the Applied Biosystems group will be able to do so as
quickly as needed. Also, the Applied Biosystems group does not expect to replace the supply of all
items purchased from Delphi and accordingly some of its older, low demand products will be
discontinued earlier than originally planned.
A significant portion of sales depends on customers capital spending policies that may be subject
to significant and unexpected decreases. A significant portion of the Applied Biosystems groups
instrument product sales are capital purchases by its customers. The Applied Biosystems groups
customers include pharmaceutical, environmental, research, biotechnology, and chemical companies,
and the capital spending policies of these companies can have a significant effect on the demand
for the Applied Biosystems groups products. These policies are based on a wide variety of
factors,
51
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
including the resources available to make purchases, the spending priorities among various
types of research equipment, and policies regarding capital expenditures during recessionary
periods. Any decrease in capital spending or change in spending policies of these companies could
significantly reduce the demand for the Applied Biosystems groups products.
A substantial portion of the Applied Biosystems groups sales is to customers at universities or
research laboratories whose funding is dependent on both the amount and timing of funding from
government sources. As a result, the timing and amount of revenues from these sources may vary
significantly due to factors that can be difficult to forecast. Research funding for life science
research has increased more slowly during the past several years compared to previous years and has
declined in some countries, and some grants have been frozen for extended periods or otherwise
become unavailable to various institutions, sometimes without advance notice. Budgetary pressures
may result in reduced allocations to government agencies that fund research and development
activities. If government funding necessary to purchase the Applied Biosystems groups products
were to become unavailable to researchers for any extended period of time, or if overall research
funding were to decrease, the Applied Biosystems groups business could be harmed.
The Applied Biosystems group is currently, and could in the future be, subject to lawsuits,
arbitrations, investigations, and other legal actions with private parties and governmental
entities, particularly involving claims for infringement of patents and other intellectual property
rights, and it may need to obtain licenses to intellectual property from others. The Applied
Biosystems group believes that it has meritorious defenses against the claims currently asserted
against it and intends to defend them vigorously. However, the outcome of legal actions is
inherently uncertain, and the Applied Biosystems group cannot be sure that it will prevail in any
of these actions. An adverse determination in some of the Applied Biosystems groups current legal
actions, particularly the cases described below, could harm our business and financial condition.
The Applied Biosystems groups products are based on complex, rapidly developing technologies.
These products could be developed without knowledge of previously filed patent applications that
mature into patents that cover some aspect of these technologies. In addition, because patent
litigation is complex and the outcome inherently uncertain, the Applied Biosystems groups belief
that its products do not infringe valid and enforceable patents owned by others could be
successfully challenged. The Applied Biosystems group has from time to time been notified that it
may be infringing patents and other intellectual property rights of others. Also, in the course of
its business, the Applied Biosystems group may from time to time have access to confidential or
proprietary information of others, and they could bring a claim against the Applied Biosystems
group asserting that the Applied Biosystems group had misappropriated their technologies, which
though not patented are protected as trade secrets, and had improperly incorporated those
technologies into the Applied Biosystems groups products. Due to these factors, there remains a
constant risk of intellectual property litigation and other legal actions, which could include
antitrust claims, affecting the Applied Biosystems group. The Applied Biosystems group has been
made a party to litigation and has been subject to other legal actions regarding intellectual
property matters, which have included claims of violations of antitrust laws. These actions
currently include the legal proceedings described in the following paragraph, some of which, if
determined adversely, could harm our business and financial condition. To avoid or settle legal
claims, it may be necessary or desirable in the future to obtain licenses relating to one or more
products or relating to current or future technologies, and the Applied Biosystems group may not be
able to obtain these licenses or other rights on commercially reasonable terms, or at all. In some
situations settlement of claims may require an agreement to cease allegedly infringing activities.
Several legal actions have been filed against us that could affect the intellectual property rights
of the Applied Biosystems group and its products and services, including the following:
|
|
|
Enzo Biochem, Inc., Enzo Life Sciences, Inc., and Yale University have filed a
lawsuit against us alleging that we are infringing six patents due to the sale of sequencing
reagent kits, TaqMan® genotyping and gene expression assays, and the gene
expression microarrays used with the Applied Biosystems groups Expression Array System. |
|
|
|
|
Molecular Diagnostics Laboratories has filed a class action complaint against us
and Hoffmann-La Roche, Inc. alleging anticompetitive conduct in connection with the sale of
Taq DNA polymerase. The anticompetitive conduct is alleged to arise from the prosecution
and enforcement of U.S. Patent No 4,889,818. This patent is assigned to Hoffmann-La Roche,
with whom we have a commercial relationship covering, among other things, this patent and
the sale of Taq DNA polymerase. |
52
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
|
|
|
In response to patent infringement claims made by us against Stratagene
Corporation, Stratagene has filed counterclaims seeking declaratory judgment that our U.S.
Patent No. 6,814,934 in the field of real-time PCR is invalid and not infringed. |
|
|
|
|
In response to a claim that we, MDS, Inc., and our Applied Biosystems/MDS Sciex
Instruments joint venture with MDS filed against Thermo Electron Corporation, Thermo
Electron has filed a counterclaim seeking a
declaratory judgment that our U.S. Patent No. 4,963,736 is invalid. After the filing of this
action against Thermo Electron, its subsidiary Thermo Finnigan LLC filed a lawsuit against us
alleging that we are infringing one of its patents as a result of, for example, the Applied
Biosystems groups commercialization of the ABI PRISM® 3700 Genetic Analyzer.
Thermo Finnigan subsequently filed a second lawsuit against us, MDS, and the Applied
Biosystems/MDS Sciex Instruments joint venture alleging that we and the other defendants have
infringed one of Thermo Finnigans patents as a result of, for example, our commercialization
of the API 5000 LC/MS/MS system. |
These cases are described in further detail in Part I, Item 3, of our 2006 Annual Report on Form
10-K under the heading Legal Proceedings Commercial Litigation, as updated by the information
in Part II, Item 1 of our subsequent Quarterly Reports on Form 10-Q, including Part II, Item 1 of
this report. The cost of litigation and the amount of management time associated with these cases
is expected to be significant. These matters might not be resolved favorably. If they are not
resolved favorably, we could be enjoined from selling the products or services in question or other
products or services as a result and monetary or other damages could be assessed against us. These
outcomes could harm the business or financial condition of our company, the Applied Biosystems
group, or the Celera group.
Some of the intellectual property that is important to our business is owned by other companies or
institutions and licensed to us, and legal actions against them could harm the Applied Biosystems
groups business. Even if the Applied Biosystems group is not a party to these legal actions, an
adverse outcome could harm our business because it might prevent these other companies or
institutions from continuing to license intellectual property that we may need for our business.
Furthermore, an adverse outcome could result in infringement or other legal actions being brought
directly against us. For example, on November 8, 2006, a patent interference proceeding was
declared by the United States Patent and Trademark Office between Enzo Diagnostics, Inc. and the
California Institute of Technology, or Caltech, concerning a patent application owned by Enzo and
U.S. Patent No. 5,821,058, owned by Caltech. The 058 patent is exclusively licensed to us and
claims methods for DNA sequencing. The Patent Office has declared the interference in order to
resolve competing claims to inventorship of the subject matter of the interference. Although we
are not a party to this proceeding, as exclusive licensee we are involved in the prosecution of the
interference, in cooperation with Caltech, and we are funding a substantial portion of the cost of
the prosecution. If Enzo prevails in the interference, the Patent Office could revoke the claims
of the 058 patent from Caltech and award substantially similar claims to Enzo, which Enzo might
then assert against our DNA sequencing products and possibly other products.
The Applied Biosystems group may become involved in legal proceedings to enforce its intellectual
property rights. The intellectual property rights of biotechnology companies, including the
Applied Biosystems group, involve complex factual, scientific, and legal questions. Even though
the Applied Biosystems group may believe that it has a valid patent on a particular technology,
other companies have from time to time taken, and may in the future take, actions that the Applied
Biosystems group believes violate its patent rights. Although the Applied Biosystems group has
licensing programs to provide industry access to some of its patent rights, other companies have in
the past refused to participate in these licensing programs and companies may refuse to participate
in them in the future, resulting in a loss of potential licensing revenue. Legal actions to
enforce these patent rights can be expensive and may involve the diversion of significant
management time. In addition, these legal actions could be unsuccessful and could also result in
the invalidation of some of the Applied Biosystems groups intellectual property rights.
Since the Applied Biosystems groups business is dependent on foreign sales, fluctuating currencies
will make revenues and operating results more volatile. Approximately 55% of the Applied
Biosystems groups net revenues for our 2006 fiscal year were derived from sales to customers
outside of the U.S. The majority of these sales were based on the relevant customers local
currency. A significant portion of the related costs for the Applied Biosystems group are based on
the U.S. dollar. As a result, the Applied Biosystems groups reported and anticipated operating
results and cash flows are subject to fluctuations due to material changes in foreign currency
exchange rates that are beyond the Applied Biosystems groups control.
53
APPLERA CORPORATION
MANAGEMENTS DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF
OPERATIONS continued
The future growth of the Applied Biosystems group depends in part on its ability to acquire
complementary technologies through acquisitions, investments, or other strategic relationships or
alliances, which may absorb significant resources, may be unsuccessful, and could dilute holders of
Applera-Applied Biosystems stock. Acquisitions, investments and other strategic relationships and
alliances, if pursued, may involve significant cash expenditures, debt incurrence, and expenses
that could have a material effect on the Applied Biosystems groups financial condition and
operating results. If these
types of transactions are pursued, it may be difficult for the Applied Biosystems group to complete
these transactions quickly and to integrate these acquired operations efficiently into its current
business operations. Potential technological advances resulting from the integration of
technologies may not be achieved as successfully or rapidly as anticipated, if at all. Any
acquisitions, investments or other strategic relationships and alliances by the Applied Biosystems
group may ultimately harm its business and financial condition. In addition, future acquisitions
may not be as successful as originally anticipated and may result in impairment charges. We have
incurred these charges in recent years in relation to acquisitions. For example, we incurred
charges for impairment of goodwill, intangibles and other assets and other charges in the amounts
of $25.9 million during our 2002 fiscal year and $4.5 million during our 2005 fiscal year in
relation to the Celera groups acquisition of Paracel, Inc. Similarly, we incurred charges for the
impairment of patents and acquired technology in the amount of $14.9 million during our 2004 fiscal
year in relation to the Applied Biosystems groups acquisition of Boston Probes, Inc.
Additionally, during our 2006 fiscal year we incurred charges, including for severance and benefit
costs and asset impairments, relating to the Celera groups acquisition of Axys Pharmaceuticals,
Inc. These charges were included within a charge of $26.4 million related to the Celera groups
decision to partner or sell its small molecule drug discovery and development programs and the
integration of Celera Diagnostics into the Celera group. In addition, acquisitions and other
transactions may involve the issuance of a substantial amount of Applera-Applied Biosystems stock
without the approval of the holders of Applera-Applied Biosystems stock. Any issuances of this
nature could be dilutive to holders of Applera-Applied Biosystems stock.
The Applied Biosystems groups businesses, particularly those focused on developing and marketing
information-based products and services, depend on the continuous, effective, reliable, and secure
operation of its computer hardware, software, and Internet applications and related tools and
functions. The Applied Biosystems groups business requires manipulating and analyzing large
amounts of data, and communicating the results of the analysis to its internal research personnel
and to its customers via the Internet. Also, the Applied Biosystems group relies on a global
enterprise software system to operate and manage its business. The Applied Biosystems groups
business therefore depends on the continuous, effective, reliable, and secure operation of its
computer hardware, software, networks, Internet servers, and related infrastructure. To the extent
that the Applied Biosystems groups hardware or software malfunctions or access to the Applied
Biosystems groups data by internal research personnel or customers through the Internet is
interrupted, the Applied Biosystems groups business could suffer.
The Applied Biosystems groups computer and communications hardware is protected through physical
and software safeguards. However, it is still vulnerable to fire, storm, flood, power loss,
earthquakes, telecommunications failures, physical or software break-ins, software viruses, and
similar events. In addition, the Applied Biosystems groups online products and services are
complex and sophisticated, and as such, could contain data, design, or software errors that could
be difficult to detect and correct. Software defects could be found in current or future products.
If the Applied Biosystems group fails to maintain and further develop the necessary computer
capacity and data to support its computational needs and its customers access to information-based
product and service offerings, it could experience a loss of or delay in revenues or market
acceptance. In addition, any sustained disruption in Internet access provided by other companies
could harm the Applied Biosystems group.
The Applied Biosystems groups operations involve the use, manufacture, sale, and distribution of
hazardous materials, and the mishandling of these hazardous materials could result in substantial
liabilities and harm to Applied Biosystems. The Applied Biosystems groups research and
development and manufacturing activities involve the controlled use of potentially hazardous
materials, including biological materials, chemicals, and various radioactive compounds. Also,
some of the Applied Biosystems groups products are hazardous materials or include hazardous
materials. The Applied Biosystems group cannot completely eliminate the risk of accidental or
other contamination or injury from these materials, and the Applied Biosystems group could be held
liable for resulting damages, which could be substantial. Under some laws and regulations, a party
can be subject to strict liability for damages caused by some hazardous materials, which means
that a party can be liable without regard to fault or negligence. In addition, the Applied
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Biosystems group is subject to federal, state, local, and foreign laws, regulations, and permits
governing the use, storage, handling, and disposal of hazardous materials and specified waste
products, as well as the shipment and labeling of materials and products containing hazardous
materials. If the Applied Biosystems group fails to comply with any of these laws, regulations, or
permits, we could be subject to substantial fine or penalty, payment of remediation costs, loss of
permits, and/or other adverse governmental action. Any of these events could harm the Applied
Biosystems groups business and financial condition.
Earthquakes could disrupt operations in California. The headquarters and principal operations of
the Applied Biosystems group are located in the San Francisco Bay area, a region near major
California earthquake faults. The ultimate impact of earthquakes on the Applied Biosystems group,
its significant suppliers, and the general infrastructure is unknown, but operating results could
be harmed if a major earthquake occurs.
Applera-Applied Biosystems stock price may be volatile. The market price of Applera-Applied
Biosystems stock has in the past been and may in the future be volatile due to the risks and
uncertainties described in this section of this report, as well as other factors that may have
affected or may in the future affect the market price, such as:
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conditions and publicity regarding the genomics, biotechnology, pharmaceutical,
or life sciences industries generally; |
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price and volume fluctuations in the stock market at large which do not relate
to Applied Biosystems operating performance; and |
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comments by securities analysts or government officials, including with regard
to the viability or profitability of the biotechnology sector generally or with regard to
intellectual property rights of life science companies, or the Applied Biosystems groups
ability to meet market expectations. |
The stock market has from time to time experienced extreme price and volume fluctuations that are
unrelated to the operating performance of particular companies. In the past, companies that have
experienced volatility have sometimes been the subjects of securities class action litigation. If
litigation was instituted on this basis, it could result in substantial costs and a diversion of
managements attention and resources.
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Risks Relating to the Celera Group
The Celera group has incurred net losses to date and may not achieve profitability. The Celera
group has accumulated net losses of approximately $864 million as of December 31, 2006. These
cumulative losses are expected to increase as the Celera group continues to make investments in new
technology and diagnostic product discovery and development, and therapeutic target discovery. As
an early stage business, the Celera group faces significant challenges in expanding its business
operations. As a result, the Celera group may not be able to achieve profitable operations when
expected, if at all.
The Celera groups diagnostics business is substantially dependent on a strategic alliance
agreement with Abbott Laboratories. The Celera group entered into this agreement with Abbott for
the joint discovery, development, manufacturing, and commercialization of nucleic acid-based, or
molecular, diagnostic products. Although this is a long-term alliance, the alliance agreement
contains provisions that could result in early termination for reasons that include the following:
breach by either company; a change in control of either company; or either companys
dissatisfaction with the financial performance of the alliance according to specifically-agreed
parameters and a measurement period set forth in the alliance agreement. In addition, the amount
and timing of resources to be devoted to research, development, eventual clinical trials and
commercialization activities by Abbott are generally not within the Celera groups control. Future
strategic alliances, if any, with other companies are likely to be subject to similar terms and
conditions.
The Celera groups diagnostic product business is dependent on entering into other collaborations,
alliances, and similar arrangements with other companies. The Celera groups strategy for the
discovery, development, clinical testing, manufacturing and/or commercialization of most of its
diagnostic product candidates includes entering into these types of arrangements with other
companies, in addition to its strategic alliance with Abbott Laboratories. Although the Celera
group has expended, and continues to expend, time and money on internal research and development
programs, it may be unsuccessful in creating diagnostic product candidates that would enable it to
form additional collaborations and alliances and, if applicable, receive milestone and/or royalty
payments from collaborators. Other companies may not be interested in entering into these
relationships with Celera, or may not be interested in doing so on terms that we consider
acceptable.
The Celera group lacks the capability to develop or commercialize therapeutic products. Although
the Celera group continues to conduct therapeutic target discovery research, it lacks the personnel
or other resources necessary to develop any potential therapeutic products for those targets, to
conduct clinical trials, or to manufacture, market or sell therapeutic products. As a result, for
the foreseeable future the Celera group expects that it will be able to develop, or participate in
the development of, therapeutic products for targets that it discovers and validates only by
collaborating with other companies or by licensing validated targets to other companies. The
Celera group may be unsuccessful in discovering and validating therapeutic targets to enable it to
form these collaborations or enter into these licenses and, if applicable, receive license,
milestone and/or royalty payments from collaborators or licensees. Other companies may not be
interested in entering into these relationships with the Celera group, or may not be interested in
doing so on terms that we consider acceptable.
The Celera groups diagnostics business, and its commercialization of discovered therapeutic
targets, could be harmed if collaborators or licensees fail to perform under their agreements with
the Celera group or if they terminate those agreements. Each of the Celera groups existing
collaboration, license, and similar agreements with other companies for the development and
commercialization of products may be canceled under some circumstances. In addition, the amount
and timing of resources to be devoted to research, development, clinical trials, and
commercialization activities by the Celera groups collaborators and licensees are generally not
within the Celera groups control. The Celera group expects that collaboration, license, and
similar agreements entered into in the future, if any, will have similar terms and limitations.
Furthermore, even if these agreements contain commitments regarding these activities, the Celera
groups collaborators or licensees may not perform their obligations as expected. If collaborators
or licensees terminate their agreements or otherwise fail to conduct their collaborative or
licensed activities in a timely manner or at all, the development or commercialization of
diagnostic or therapeutic products may be delayed or prevented. If the Celera group assumes
responsibilities for continuing diagnostic programs on its own after termination of a
collaboration, license, or similar agreement, the Celera group may be required to devote additional
resources to product development and commercialization or the Celera group may need to cancel some
development programs. If a collaboration, license, or other agreement for a therapeutic program is
terminated, the Celera group would not be able to assume responsibility for
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the continued development of that program because it lacks the resources for therapeutic product
development, and the only way it could continue that program would be to find another collaborator
or licensee.
The Celera groups efforts to discover diagnostic markers and therapeutic targets depend, in part,
on the use of novel and unproven discovery methods. It is therefore possible that the Celera
groups discovery efforts will not result in any new diagnostic markers or therapeutic targets that
could be developed into commercial diagnostic or therapeutic products. The Celera group and its
collaborators are seeking to identify diagnostic markers that can be used to develop new diagnostic
products based on information derived from the study of the genetic material of organisms, or
genomics. This method carries inherent risks, as only a limited number of diagnostic products
based on genomic discoveries have been developed and commercialized to date. Also, the Celera
group is seeking to identify novel targets for the development of new treatments for disease
through the use of technology in the field of proteomics, the study of proteins, and using disease
association findings arising from its genomics research. To our knowledge, neither of these
approaches to target discovery has to date been effectively used to develop a therapeutic product
that has been commercialized, and therefore the potential benefit to the Celera group of its use of
proteomics technology and disease association study information to support therapeutic target
discovery is unknown.
For some of the Celera groups diagnostic research and product development programs and therapeutic
target discovery research programs, the Celera group needs access to human tissue and/or blood
samples from diseased and healthy individuals, other biological materials, and related clinical and
other information, which may be in limited supply. The Celera group may not be able to obtain or
maintain access to these materials and information on acceptable terms, or may not be able to
obtain needed consents from individuals providing tissue, blood, or other samples. In addition,
government regulation in the U.S. and foreign countries could result in restricted access to, or
use of, human tissue or blood samples or other biological materials. If the Celera group loses
access to sufficient numbers or sources of tissue or blood samples or other required biological
materials, or if tighter restrictions are imposed on the use of related clinical or other
information or information generated from tissue or blood samples or other biological materials,
these research and development programs and the Celera groups business could be harmed.
Our diagnostic product candidates may never result in a commercialized product. Most of the Celera
groups diagnostic product candidates are in various stages of research and development and the
ability to commercialize those product candidates, including through collaborators or licensees, is
highly uncertain. Development of existing product candidates will require significant additional
research and development efforts by the Celera group or its collaborators or licensees before they
can be marketed. For potential diagnostic products, these efforts include extensive clinical
testing to confirm the products are safe and effective and may require lengthy regulatory review
and clearance or approval by the U.S. Food and Drug Administration and comparable agencies in other
countries. Furthermore, even if these products are found to be safe and effective and receive
necessary regulatory clearances or approvals, they may never be developed into commercial products
due to considerations such as: inability to obtain needed licenses to intellectual property owned
by others; market and competitive conditions; and manufacturing difficulties or cost
considerations.
If the Celera group or its collaborators or licensees fail to satisfy regulatory requirements for
any diagnostic product candidate, the Celera group or its collaborators or licensees may be unable
to complete the development and commercialization of that product. The Celera group is currently
developing its internal capability to move potential diagnostic products through clinical testing,
manufacturing, and the approval processes of the U.S. Food and Drug Administration, and comparable
agencies in other countries. In the U.S., either the Celera group or its collaborators or
licensees must show through pre-clinical studies and clinical trials that each of the Celera
groups or its collaborators or licensees diagnostic product candidates is safe and effective for
each indication before obtaining regulatory clearance or approval from the FDA for the commercial
sale of that product as an in vitro diagnostic product with clinical claims. Outside of the U.S.,
the regulatory requirements for commercialization vary from country to country. If the Celera
group or its collaborators or licensees fail to adequately show the safety and effectiveness of a
diagnostic product candidate, regulatory clearance or approval could be delayed or denied. The
results from pre-clinical studies may be different from the results that are obtained in clinical
trials, and the Celera group or its collaborators or licensees may not be able to show sufficient
safety and effectiveness in their clinical trials to allow them to obtain the needed regulatory
clearance or approval. The regulatory review and approval process can take many years and require
substantial expense and may not be successful.
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The U.S. Food and Drug Administration has issued a draft interpretation of the regulations
governing the sale of Analyte Specific Reagent products which could prevent or delay our or our
collaborators or licensees sales of these products and harm our business. In September 2006, the
U.S. Food and Drug Administration, or FDA, published Draft Guidance for Industry and FDA Staff:
Commercially Distributed Analyte Specific Reagents (ASRs): Frequently Asked Questions clarifying
the FDAs interpretation of the regulations governing the sale of Analyte Specific Reagent, or ASR,
products. ASRs are a class of products that do not require regulatory clearance or approval. The
draft guidance document contains an interpretation of the ASR regulations that is a departure from
what we believe to be the existing FDA practice and policy regarding products that can be
characterized as ASRs. If this draft guidance document becomes the final guidance document, and if
the FDA begins enforcing this interpretation of the ASR regulations, the Celera groups current ASR
products may not meet the regulatory definition of an ASR. If this were to occur, the Celera group
or its alliance partner Abbott Laboratories might have to stop selling these ASR products until the
products receive, if possible, the applicable FDA approval or clearance. Furthermore, the
enforcement of this new interpretation might prevent the Celera group or its collaborators or
licensees from developing any new products that would qualify as ASRs.
Even if the Celera group or its collaborators or licensees obtain regulatory clearance or approval
for a particular diagnostic product, that product will remain subject to ongoing regulatory
requirements, and our inability to meet these requirements could prevent or require us to suspend
commercialization of a product. The manufacture of our and our collaborators and licensees
diagnostic products is subject to the U.S. Food and Drug Administrations Quality System
Regulation. The occurrence of manufacturing problems for any product, including the inability to
comply with this regulation, could result in withdrawal of regulatory clearance or approval for
that product, and could also force us or our collaborators or licensees to suspend manufacturing
of, reformulate, conduct additional testing for, and/or change the labeling for, that product.
This could delay or prevent the Celera group from generating revenues from the sale of any affected
diagnostic product.
Clinical trials of diagnostic product candidates may not be successful. Potential clinical trials
may not begin on time, may not be completed on schedule, or at all, or may not be sufficient for
registration of the products or result in products that can receive necessary clearances or
approvals. Numerous unforeseen events during, or as a result of, clinical testing could delay or
prevent commercialization of the Celera groups or its collaborators or licensees diagnostic
product candidates. Diagnostic product candidates that appear to be promising at early stages of
development or early clinical trials may later be found to be unsafe, ineffective, or to have
limited medical value.
Collaborators or licensees may never successfully develop and commercialize therapeutic product
candidates. The development and commercialization of therapeutic products by collaborators or
licensees is highly uncertain and subject to a number of significant risks. Therapeutic product
candidates that appear to be promising at early stages of development may later be found to be
unsafe, ineffective, or to have limited medical value. These product candidates must undergo
expensive and time consuming clinical trials to determine whether they are safe and effective, and
then they are subject to a lengthy regulatory review for approval by the U.S. Food and Drug
Administration and comparable agencies in other countries. Furthermore, even if these products are
found to be safe and effective and receive regulatory approvals, they may never be developed into
commercial products due to considerations such as: inability to obtain needed licenses to
intellectual property owned by others; market and competitive conditions; and manufacturing
difficulties or cost considerations. Accordingly, the Celera group may not receive any license,
milestone, royalty, or other payments or any other benefit from collaboration, license, or similar
agreements for the development of therapeutic products based on targets identified and validated by
the Celera group.
The Celera group lacks sales capability in the clinical diagnostics market. The Celera group
currently lacks a sales organization for its diagnostic products. Accordingly, its ability to
successfully sell these products depends on its ability to develop a sales organization, work with
Abbott Laboratories under the existing strategic alliance agreement that is described above, work
with another distributor, or pursue a combination of these alternatives. In jurisdictions where
the Celera group uses others as distributors for its diagnostic products, its success in marketing
these products depends to a great extent on the efforts of the distributors.
The Celera group has limited manufacturing experience and capability for its diagnostic products
and may encounter difficulties expanding the operations of its diagnostic products business. If
diagnostic product sales or clinical trial usage needs increase, the Celera group may have to
increase the capacity of its diagnostic product manufacturing processes and
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facilities or rely on
its collaborators, if any, in this field of business. The Celera group may encounter difficulties
in
scaling-up diagnostic product manufacturing processes and may be unsuccessful in overcoming these
difficulties. In these circumstances, the Celera groups ability to meet diagnostic product demand
or clinical trial usage needs may be impaired or delayed.
The Celera groups diagnostic product manufacturing facilities are subject, on an ongoing basis, to
the U.S. Food and Drug Administrations Quality System Regulation, international quality standards
and other regulatory requirements, including requirements for good manufacturing practices, and the
State of California Department of Health Services Food and Drug Branch requirements. The Celera
group may encounter difficulties expanding its diagnostic product manufacturing operations in
accordance with these regulations and standards, which could result in a delay or termination of
manufacturing or an inability to meet product demand or clinical trial usage needs.
The Celera groups diagnostic product manufacturing operations are located in a facility in
Alameda, California. The Celera group expects to operate its diagnostic product manufacturing out
of this facility for the foreseeable future, and it lacks alternative production plans in place or
alternative facilities available should its existing manufacturing facility cease to function.
Accordingly, the Celera groups diagnostic product business could be harmed by unexpected
interruptions in manufacturing caused by events such as labor problems, equipment failures, or
other factors, and the resulting inability to meet customer orders or clinical trial usage needs on
a timely basis.
Single suppliers or a limited number of suppliers provide key components of the Celera groups
diagnostic products. If these suppliers fail to supply these components, the Celera group may be
unable to satisfy product demand or clinical trial usage needs. Several key components of the
Celera groups products come from, or are manufactured for the Celera group by, a single supplier
or a limited number of suppliers. This applies in particular to components such as enzymes,
fluorescent dyes, phosphoramadites, and oligonucleotides. The Celera group acquires some of these
and other key components on a purchase-order basis, meaning that the supplier is not required to
supply the Celera group with specified quantities over any set period of time or set aside part of
its inventory for the Celera groups forecasted requirements. The Celera group has not arranged
for alternative supply sources for some of these components and it may be difficult to find
alternative suppliers, especially to replace enzymes and oligonucleotides. Furthermore, to
maintain compliance with the U.S. Food and Drug Administrations Quality System Regulation, the
Celera group must verify that its suppliers of key components are in compliance with all applicable
U.S. FDA regulations. The Celera group believes that compliance with these regulatory requirements
would increase the difficulty in arranging for needed alternative supply sources, particularly for
components that are from single source suppliers, which means that they are currently the only
supplier of custom-ordered components. If the Celera groups diagnostic product sales increase
beyond forecasted levels, or if its suppliers are unable or unwilling to supply items on
commercially acceptable terms or comply with regulations applicable to manufacturing of the Celera
groups diagnostic products, it may not have access to sufficient quantities of key components on a
timely basis and may be unable to satisfy product demand or clinical trial usage needs.
In addition, if any of the components of the Celera groups products are no longer available in the
marketplace, it may be forced to further develop its products or technology to incorporate
alternative components. The incorporation of new components into its diagnostic products may
require the Celera group to seek clearances or approvals from the FDA or foreign regulatory
agencies before commercialization.
The Celera groups collaborations with outside experts may be subject to restriction and change.
The Celera group collaborates with scientific and clinical experts at academic and other
institutions that provide assistance and guidance to the Celera groups research and development
efforts. These advisors and collaborators are not employees of the Celera group and may have other
commitments that limit their availability to the Celera group. Although they generally agree not
to do competing work, if a conflict of interest arises between their work for the Celera group and
their work for another company or institution, the Celera group may lose the services of these
experts. In addition, although the Celera groups advisors and collaborators sign agreements not
to disclose the Celera groups confidential information, it is possible that valuable proprietary
knowledge may become publicly known or otherwise available to other parties, including the Celera
groups competitors, through them.
The diagnostics industry is intensely competitive and evolving. There is intense competition among
healthcare, diagnostic, and biotechnology companies attempting to discover candidates for potential
new diagnostic products. The
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Celera group is aware of competitors who are engaged in research and
development projects that address the diseases that the Celera group is targeting. These companies
may:
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develop new diagnostic products in advance of the Celera group or its collaborators or
licensees; |
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develop products that are more effective diagnostic products, or more cost-effective,
than those developed by the Celera group or its collaborators or licensees; |
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obtain regulatory clearances or approvals of their diagnostic products more rapidly than
the Celera group or its collaborators or licensees; or |
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obtain patent protection or other intellectual property rights that would limit the
ability of the Celera group or its collaborators or licensees to develop and commercialize
diagnostic products, or that would limit the ability of customers to use those products. |
The Celera groups diagnostic products business competes with companies in the U.S. and abroad that
are engaged in the development and commercialization of products and services that provide genetic
information. These companies may develop products or services that are competitive with the
diagnostic products offered by the Celera group or its collaborators or licensees, such as analyte
specific reagents, diagnostic test kits, or diagnostic testing services that perform the same or
similar purposes as the Celera groups or its collaborators or licensees diagnostic products.
Also, clinical laboratories may offer testing services that are competitive with the diagnostic
products sold by the Celera group or its collaborators or licensees. For example, a clinical
laboratory can use either reagents purchased from manufacturers other than the Celera group, or use
their own internally developed reagents, to make diagnostic tests. If clinical laboratories make
tests in this manner for a particular disease, they could offer testing services for that disease
as an alternative to diagnostic products sold by the Celera group or its collaborators or licensees
for use in the testing of the same disease. The testing services offered by clinical laboratories
may be easier to develop and market than test kits developed by the Celera group or its
collaborators or licensees because the testing services are not subject to the same clinical
validation requirements that are applicable to U.S. Food and Drug Administration cleared or
approved diagnostic test kits. The diagnostic testing services market is dominated by a small
number of large clinical laboratories, including Laboratory Corporation of America Holdings, Quest
Diagnostics Inc., and Specialty Laboratories, Inc.
Also, a substantial portion of all sales of diagnostic products are made to a small number of
clinical reference laboratories, including those identified above, and therefore the Celera group
expects to rely on these laboratories for a substantial portion of its diagnostics business sales.
The Celera groups inability to establish or maintain one or more of these laboratories as a
customer could harm its business, financial condition, and operating results.
The Celera groups diagnostic products may not be fully accepted by physicians and laboratories.
The growth and success of the Celera groups diagnostics business depends on market acceptance by
physicians and laboratories of its products as clinically useful and cost-effective. The Celera
group expects that most of its diagnostic products will use genotyping and gene expression
information to predict predisposition to diseases, disease progression or severity, or
responsiveness to treatment. Market acceptance depends on the widespread acceptance and use by
doctors and clinicians of genetic testing for these purposes. The use of genotyping and gene
expression information by doctors and clinicians for these purposes is relatively new. Doctors and
clinicians may not want to use the Celera groups products designed for these purposes.
Even if genetic testing is accepted as a method to manage healthcare, the Celera groups diagnostic
products may not be accepted in the clinical diagnostics market. If genetic testing becomes widely
accepted in the clinical diagnostics market, the Celera group cannot predict the extent to which
doctors and clinicians may be willing to use the Celera groups diagnostic products in providing
patient care. Doctors and clinicians may prefer competing technologies and products that can be
used for the same purposes as the Celera groups products.
If insurance companies and other third-party payors do not reimburse doctors and patients for the
Celera groups diagnostic tests, its ability to sell its products to the clinical diagnostics
market will be impaired. Sales of the Celera groups diagnostic products will depend, in large
part, on the availability of adequate reimbursement to users of those products from government
insurance plans, including Medicare and Medicaid in the U.S., managed care organizations, and
private insurance plans. Physicians recommendations to use diagnostic tests, as well as decisions
by patients to pursue those tests, are likely to be influenced by the availability of reimbursement
by insurance companies and other
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third-party payors. Third-party payors are increasingly
attempting to contain healthcare costs by limiting both the extent of coverage and the
reimbursement rate for testing and treatment products and services. In particular, products and
services that are determined to be investigational in nature or that are not considered reasonably
necessary for diagnosis
or treatment may be denied reimbursement coverage. In addition, third-party payors are
increasingly limiting reimbursement coverage for medical diagnostic products and, in many
instances, are exerting pressure on medical suppliers to reduce their prices. Thus, third-party
reimbursement may not be consistently available or financially adequate to cover the cost of the
Celera groups diagnostic products. This could limit the ability of the Celera group to sell its
diagnostic products, cause the Celera group to reduce the prices of its products, or otherwise harm
the Celera groups operating results.
Because each third-party payor individually approves reimbursement, obtaining these approvals is a
time-consuming and costly process. The Celera group must provide scientific and clinical support
for the use of each of its diagnostic products to each payor separately with no assurance that they
will provide their approval for reimbursement. This process can delay the broad market
introduction of new products and could have a negative effect on the Celera groups revenues and
operating results.
Introduction of new diagnostic and therapeutic products may expose the Celera group to product
liability claims. New products developed by the Celera group or its collaborators or licensees
could expose the Celera group to potential product liability risks that are inherent in the
testing, manufacturing, marketing, and sale of human diagnostic and therapeutic products. In
addition, clinicians, patients, third-party payors, and others may at times seek damages based on
testing or analysis errors caused by a technicians misreading of results, mishandling of the
patient samples, or similar claims. Product liability claims or product recalls, regardless of the
ultimate outcome, could require the Celera group to spend significant time and money in litigation
and to pay significant damages. Although the Celera group expects to seek and maintain product
liability insurance to cover claims relating to the testing and use of diagnostic and therapeutic
products, it may not be able to obtain the insurance on commercially reasonable terms, if at all,
or it may not be able to obtain coverage in an amount that will be adequate to cover losses from
any particular claim. Also, although the Celera group expects that it will be involved in the
commercialization of therapeutic products only through other companies who develop and market those
products under collaboration, license, or similar agreements, the Celera group could be indirectly
exposed to product liability claims under applicable laws or regulations or due to the terms and
conditions of those agreements.
The Celera groups operations involve the use, manufacture, sale, and distribution of hazardous
materials, and the mishandling of these hazardous materials could result in substantial liabilities
and harm to the Celera group. The Celera groups diagnostic and therapeutic research and
development activities, and diagnostic manufacturing activities, involve the controlled use of
potentially hazardous materials, including biological materials, chemicals, and various radioactive
compounds. Also, some of the Celera groups diagnostic products, including products sold through
its strategic alliance with Abbott Laboratories, are hazardous materials or include hazardous
materials. The Celera group cannot completely eliminate the risk of accidental or other
contamination or injury from these materials, and the Celera group could be held liable for
resulting damages, which could be substantial. Under some laws and regulations, a party can be
subject to strict liability for damages caused by some hazardous materials, which means that a
party can be liable without regard to fault or negligence. Furthermore, the Celera group could be
held indirectly responsible for contamination or injury arising from the conduct of Abbott
Laboratories in manufacturing, selling, or distributing alliance diagnostic products. The Celera
group could be held similarly responsible for the actions of its other collaborators or licensees.
In addition, the Celera group is subject to federal, state, local, and foreign laws, regulations,
and permits governing the use, storage, handling, and disposal of hazardous materials and specified
waste products, as well as the shipment and labeling of materials and products containing hazardous
materials. If the Celera group fails to comply with any of these laws, regulations, or permits, or
if the Celera group is held indirectly responsible for conduct of Abbott Laboratories or other
collaborators or licensees found to be non-compliant, we could be subject to substantial fine or
penalty, payment of remediation costs, loss of permits, and/or other adverse governmental action.
Any of these events could harm the Celera groups business and financial condition.
The Celera groups business depends on the continuous, effective, reliable, and secure operation of
its computer hardware, software, and Internet applications and related tools and functions. The
Celera groups business requires manipulating and analyzing large amounts of data, and
communicating the results of the analysis to its internal research
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personnel and its collaborators
via the Internet. Also, the Celera group relies on a global enterprise software system to operate
and manage its business. The Celera groups business therefore depends on the continuous,
effective, reliable, and secure operation of its computer hardware, software, networks, Internet
servers, and related infrastructure. To the extent that the Celera groups hardware or software
malfunctions or access to the Celera groups data by the Celera
groups internal research personnel or collaborators through the Internet is interrupted, the
Celera groups business could suffer.
The Celera groups computer and communications hardware is protected through physical and software
safeguards. However, it is still vulnerable to fire, storm, flood, power loss, earthquakes,
telecommunications failures, physical or software break-ins, software viruses, and similar events.
If the Celera group fails to maintain and further develop the necessary computer capacity and data
to support its and its collaborators and licensees discovery, research, and development
activities, including its associated computational needs, it could experience a loss of or delay in
revenues. In addition, any sustained disruption in Internet access provided by other companies
could harm the Celera groups business.
The Celera groups competitive position depends on maintaining its intellectual property
protection. The Celera groups ability to compete and to achieve and maintain profitability
depends, in part, on its ability to protect its proprietary discoveries and technologies through
obtaining and enforcing patent rights, obtaining copyright protection, maintaining its trade
secrets, and operating without infringing the intellectual property rights of others. The Celera
groups ability to obtain patent protection for the inventions it makes, including those relating
to novel methods of diagnosing and/or treating diseases, is uncertain. The patentability of these
and other types of biotechnology inventions involves complex factual, scientific, and legal
questions. As a result, it is difficult to predict whether patents will issue or the breadth of
claims that will be allowed in biotechnology patents. This may be particularly true with regard to
the patenting of gene sequences, gene functions, and genetic variations. In this regard, the U.S.
Patent and Trademark Office has adopted guidelines for use in the review of the utility of
inventions, particularly biotechnology inventions. These guidelines increased the amount of
evidence required to demonstrate utility to obtain a patent in the biotechnology field, making
patent protection more difficult to obtain. Also, future changes in policies or laws, or
interpretations of these policies or laws, relevant to the patenting of biotechnology inventions
could harm our patent position in the U.S. or other countries. Opposition to the protection of
these inventions in the U.S. or other countries could result in stricter standards for obtaining or
enforcing biotechnology patent rights.
In some instances, patent applications in the U.S. are maintained in secrecy until a patent issues.
In most instances, the content of U.S. and international patent applications is made available to
the public approximately 18 months after the initial filing from which priority is claimed. As a
result, the Celera group may not be aware that others have filed patent applications for inventions
covered by the Celera groups patent applications and may incorrectly believe that the Celera group
inventors were the first to make the invention. Accordingly, the Celera groups patent
applications may be preempted or the Celera group may have to participate in interference
proceedings before the U.S. Patent and Trademark Office. These proceedings determine the priority
of invention and the right to a patent for the claimed invention in the U.S.
The Celera group also relies on trade secret protection for its confidential and proprietary
information and procedures, including procedures related to sequencing genes and to searching and
identifying important regions of genetic information. The Celera group protects its trade secrets
through recognized practices, including access control, confidentiality and non-use agreements with
employees, consultants, collaborators and customers, and other security measures. These
confidentiality and non-use agreements may be breached, however, and the Celera group may not have
adequate remedies for a breach. In addition, the Celera groups trade secrets may otherwise become
known or be independently developed by competitors. Accordingly, it is uncertain whether the
Celera groups reliance on trade secret protection will be adequate to safeguard its confidential
and proprietary information and procedures.
Disputes may arise in the future with regard to the ownership of rights to any invention developed
with collaborators. These and other possible disagreements with collaborators could lead to delays
in the achievement of milestones or receipt of royalty payments or in research, development and
commercialization of the Celera groups or its collaborators diagnostic products. In addition,
these disputes could require or result in lawsuits or arbitration. Lawsuits and arbitration are
time-consuming and expensive. Even if the Celera group wins, the cost of these proceedings could
harm its business, financial condition, and operating results.
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The Celera group may infringe the intellectual property rights of others, may become involved in
expensive intellectual property legal proceedings, and may need to obtain licenses to intellectual
property from others. There has been substantial litigation and other legal proceedings regarding
patents and other intellectual property rights in the biotechnology, pharmaceutical, and
diagnostics industries. The intellectual property rights of biotechnology companies,
including the Celera group, are generally uncertain and involve complex factual, scientific, and
legal questions. The Celera groups success in diagnostic product development and therapeutic
target discovery may depend, in part, on its ability to operate without infringing the intellectual
property rights of others and to prevent others from infringing its intellectual property rights.
Also, contractual disputes related to existing license rights to patents owned by others may affect
the Celera groups ability to develop, manufacture, and sell its products.
The Celera group may initiate proceedings at the U.S. Patent and Trademark Office to determine its
patent rights with respect to others, referred to as interference proceedings. Also, the Celera
group may initiate patent litigation to enforce its patent rights or invalidate patents held by
others. These legal actions may similarly be initiated against the Celera group by others alleging
that the Celera group is infringing their rights. The cost to the Celera group of any patent
litigation or proceedings, even if the Celera group is successful, could be substantial, and these
legal actions may absorb significant management time.
If infringement claims against the Celera group are resolved unfavorably to the Celera group, the
Celera group may be enjoined from manufacturing or selling its products or services without a
license from a third party, and the Celera group may not be able to obtain a license on
commercially acceptable terms, or at all. Also, the Celera group could become subject to
significant liabilities to others if these claims are resolved unfavorably to the Celera group.
Similarly, our business could be harmed and we could be subject to liabilities because of lawsuits
brought by others against Abbott Laboratories, with whom we have a strategic alliance. For
example, Abbott has been sued by Innogenetics N.V. for patent infringement due to Abbotts sale of
hepatitis C virus genotyping analyte specific reagents, or ASRs, manufactured by the Celera group
for Abbott. In September 2006, a jury rendered a verdict against Abbott and awarded $7 million in
monetary damages to Innogenetics. We have agreed to share the cost of this litigation, including
these damages, and we are also subject to a permanent injunction that was issued by the court after the jury
verdict, in January 2007, that prohibits us or Abbott from manufacturing or selling hepatitis C
virus genotyping ASRs. Abbott has notified us that it intends to appeal the verdict in this case,
and it has filed an emergency motion with a Federal Court of Appeals seeking a stay of the
permanent injunction during the appeal process, but Abbott may not be successful. Abbott has
obtained a temporary stay of the permanent injunction pending the Courts consideration of the
emergency motion for a stay of the permanent injunction.
Ethical, legal, and social issues related to the use of genetic information and genetic testing may
cause less demand for the Celera groups diagnostic products. Genetic testing has raised issues
regarding confidentiality and the appropriate uses of the resulting information. For example,
concerns have been expressed regarding the use of genetic test results by insurance carriers or
employers to discriminate on the basis of this information, resulting in barriers to the acceptance
of genetic tests by consumers. This could lead to governmental authorities calling for limits on
or regulation of the use of genetic testing or prohibiting testing for genetic predisposition to
some diseases, particularly those that have no known cure. Any of these scenarios could reduce the
potential markets for products of the Celera group.
The Celera group may pursue acquisitions, investments, or other strategic relationships or
alliances, which may consume significant resources, may be unsuccessful, and could dilute the
holders of Applera-Celera stock. Acquisitions, investments and other strategic relationships and
alliances, if pursued, may involve significant cash expenditures, debt incurrence, additional
operating losses, and expenses that could have a material effect on the Celera groups financial
condition and operating results. Acquisitions involve numerous other risks, including:
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entry into new markets in which the Celera group has little previous experience; |
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potential loss of key employees, key contractual relationships, or key customers of
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assumption of the liabilities and exposure to unforeseen liabilities of acquired
companies. |
If these types of transactions are pursued, it may be difficult for the Celera group to complete
these transactions quickly and to integrate these acquired operations efficiently into its current
business operations. Any acquisitions, investments or other strategic relationships and alliances
by the Celera group may ultimately harm its business and financial condition. In addition, future acquisitions may not be as successful as originally anticipated and may result
in impairment charges. We have incurred these charges in recent years in relation to acquisitions.
For example, we incurred charges for impairment of goodwill, intangibles and other assets and
other charges in the amounts of $25.9 million during our 2002 fiscal year and $4.5 million during
our 2005 fiscal year in relation to the Celera groups acquisition of Paracel, Inc. Similarly, we
incurred charges for the impairment of patents and acquired technology in the amount of $14.9
million during our 2004 fiscal year in relation to the Applied Biosystems groups acquisition of
Boston Probes, Inc. Additionally, during our 2006 fiscal year we incurred charges, including for
severance and benefit costs and asset impairments, relating to the Celera groups acquisition of
Axys Pharmaceuticals, Inc. These charges were included within a charge of $26.4 million related to
the Celera groups decision to partner or sell its small molecule drug discovery and development
programs and the integration of Celera Diagnostics into the Celera group.
In addition, acquisitions and other transactions may involve the issuance of a substantial amount
of Applera-Celera stock without the approval of the holders of Applera-Celera stock. Any issuances
of this nature could be dilutive to holders of Applera-Celera stock.
Earthquakes could disrupt operations in California. The Celera group has headquarters, research
and development, manufacturing, and administrative facilities in Alameda, California. Alameda is
located near major California earthquake faults. The ultimate impact of earthquakes on the Celera
group, its significant suppliers, and the general infrastructure is unknown, but operating results
could be harmed if a major earthquake occurs.
Applera-Celera stock price may be volatile. The market price of Applera-Celera stock has in the
past been and may in the future be volatile due to the risks and uncertainties described in this
section of this report, as well as other factors that may have affected or may in the future affect
the market price, such as:
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conditions and publicity regarding the genomics, biotechnology, pharmaceutical,
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price and volume fluctuations in the stock market at large which do not relate to the
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comments by securities analysts or government officials, including with regard to the
viability or profitability of the biotechnology sector generally or with regard to
intellectual property rights of life science companies, or the Celera groups ability to
meet market expectations. |
The stock market has from time to time experienced extreme price and volume fluctuations that are
unrelated to the operating performance of particular companies. In the past, companies that have
experienced volatility have sometimes been the subjects of securities class action litigation. If
litigation was instituted on this basis, it could result in substantial costs and a diversion of
managements attention and resources.
Our company is subject to a class action lawsuit relating to its 2000 offering of shares of
Applera-Celera stock that may be expensive and time consuming. Our company and some of our
officers are defendants in a lawsuit brought on behalf of purchasers of Applera-Celera stock in our
follow-on public offering of Applera-Celera stock completed on March 6, 2000. In the offering, we
sold an aggregate of approximately 4.4 million shares of Applera-Celera stock at a public offering
price of $225 per share. The lawsuit was commenced with the filing of several complaints in 2000,
which have been consolidated into a single case which has been certified by the court as a class
action. The consolidated complaint generally alleges that the prospectus used in connection with
the offering was inaccurate or misleading because it failed to adequately disclose the alleged
opposition of the Human Genome Project and two of its supporters, the governments of the U.S. and
the U.K., to providing patent protection to our genomic-based products. Although the Celera group
has never sought, or intended to seek, a patent on the basic human genome sequence data, the
complaint also alleges that we did not adequately disclose the risk that the Celera group would not
be able to patent this data. The consolidated complaint seeks unspecified monetary damages,
rescission, costs and expenses, and other relief as the court deems proper.
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Although we believe
the asserted claims are without merit and intend to defend the case vigorously, the outcome of this
or any other litigation is inherently uncertain. The defense of this case will require management
attention and resources.
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Item 3. Quantitative and Qualitative Disclosures About Market Risk.
We are exposed to potential loss from exposure to market risks represented principally by changes
in foreign exchange rates, interest rates, and equity prices. Please refer to the market risks
section of the managements discussion and analysis included on page 48 of this report. Additional
information can also be found in the market risk section of the managements discussion and
analysis included on page 36 of our 2006 Annual Report to Stockholders (which section is
incorporated in this report by reference).
Item 4. Controls and Procedures.
Disclosure Controls and Procedures
We are responsible for maintaining disclosure controls and procedures, as defined by the Securities
and Exchange Commission in its Rules 13a-15(e) and 15d-15(e) under the Securities Exchange Act of
1934. Disclosure controls and procedures are controls and other procedures designed to ensure that
the information required to be disclosed by us in the reports that we file or submit under the
Securities Exchange Act is recorded, processed, summarized, and reported within the time periods
specified in the Securities and Exchange Commissions rules and forms. Disclosure controls and
procedures include, without limitation, controls and procedures designed to ensure that information
required to be disclosed by us in the reports that we file or submit under the Securities Exchange
Act is accumulated and communicated to our management, including our Chief Executive Officer and
Chief Financial Officer, as appropriate to allow timely decisions regarding required disclosure.
Our management evaluated the effectiveness of our disclosure controls and procedures as of the end
of the second quarter of our 2007 fiscal year, the period covered by this report. Based on that
evaluation, our Chief Executive Officer and Chief Financial Officer have concluded that our
disclosure controls and procedures are effective to achieve their stated purpose. However, there
is no assurance that our disclosure controls and procedures will operate effectively under all
circumstances.
Internal Control Over Financial Reporting
We are responsible for maintaining internal control over financial reporting, as defined by the
Securities and Exchange Commission in its Rules 13a-15(f) and 15d-15(f) under the Securities
Exchange Act of 1934. Internal control over financial reporting is a process designed by, or under
the supervision of, our Chief Executive Officer and Chief Financial Officer, and effected by our
Board of Directors, management, and other personnel, to provide reasonable assurance regarding the
reliability of our financial reporting and the preparation of our financial statements for external
purposes in accordance with generally accepted accounting principles. Internal control over
financial reporting includes those policies and procedures that: (1) pertain to the maintenance of
records that in reasonable detail accurately and fairly reflect the transactions and dispositions
of our assets; (2) provide reasonable assurance that transactions are recorded as necessary to
permit preparation of financial statements in accordance with generally accepted accounting
principles, and that receipts and expenditures are being made only in accordance with
authorizations of our management and directors; and (3) provide reasonable assurance regarding
prevention or timely detection of unauthorized acquisition, use, or disposition of our assets that
could have a material effect on our financial statements. Based on an evaluation of internal
control over financial reporting by our management, we have not identified any change made to our
internal control over financial reporting during the second quarter of our 2007 fiscal year, which
is our last fiscal quarter and the period covered by this report, that have materially affected, or
are reasonably likely to materially affect, our internal control over financial reporting.
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PART II OTHER INFORMATION
Item 1. Legal Proceedings.
We are involved in various lawsuits, arbitrations, investigations, and other legal actions from
time to time with both private parties and governmental entities. These legal actions currently
involve, for example, commercial, intellectual property, antitrust, environmental, securities, and
employment matters. We disclosed information about some of our legal actions in Part I, Item 3, of
our 2006 Annual Report on Form 10-K. We made additional disclosures regarding our legal actions in
Item 1 of Part II of our previously filed Quarterly Report on Form 10-Q for the first quarter of
our current fiscal year, updating the information disclosed in our 2006 10-K. Set forth below is
an update to those disclosures, including specifically a description of the settlement of a
previously disclosed case involving On-Line Technologies. For additional information about our
legal proceedings, refer to Note 12 to our Unaudited Condensed Consolidated Financial Statements in
Part I of this report.
We believe that we have meritorious defenses against the claims currently asserted against us,
including the ongoing claims described in our 2006 10-K as updated by the disclosures in our
subsequent reports, and we intend to defend them vigorously. However, the outcome of legal actions
is inherently uncertain, and we cannot be sure that we will prevail in our defense of claims
currently asserted against us. An adverse determination in the cases we are currently defending,
particularly the claims against us described in Item 3 of our 2006 10-K under the heading
Commercial Litigation, as updated by the disclosures in our subsequent reports, could have a
material adverse effect on us, the Applied Biosystems group, or the Celera group.
On-Line Technologies, Inc. (since acquired by MKS Instruments, Inc.) filed claims for patent
infringement, trade secret misappropriation, fraud, breach of contract and unfair trade practices
against PerkinElmer, Inc., Sick UPA, GmbH, and us in the U.S. District Court for the District of
Connecticut on or about November 3, 1999. The complaint alleged that products called the Spectrum
One and the MCS100E manufactured by former divisions of the Applied Biosystems group, which
divisions were sold to the co-defendants in this case, were based on allegedly proprietary
information belonging to On-Line Technologies and that the MCS100E infringed U.S. Patent No.
5,440,143. On-Line Technologies was seeking monetary damages, costs, expenses, injunctive relief,
and other relief. On April 2, 2003, the U.S. District Court for the District of Connecticut
granted our summary judgment motion and dismissed all claims brought by On-Line Technologies.
On-Line Technologies filed an appeal with the U.S. Court of Appeals for the Federal Circuit seeking
reinstatement of its claims, and on October 13, 2004, the Court of Appeals upheld dismissal of all
claims except for the patent infringement claim, which was to be decided by the District Court in
subsequent proceedings. However, the parties settled all of these claims under an agreement that
was effective January 18, 2007, and the District Court formally dismissed the case on January 26,
2007.
Item 1A. Risk Factors.
Overview
Some statements contained in, or incorporated by reference in, this report, including the Outlook
section of Managements Discussion and Analysis of Financial Condition and Results of Operation
contained in Item 2 of Part I of this report, are forward-looking and are subject to a variety of
risks and uncertainties. Similarly, the press releases we issue and other public statements we
make from time to time may contain language that is forward-looking. These forward-looking
statements may be identified by the use of forward-looking words or phrases such as forecast,
believe, expect, intend, anticipate, should, plan, estimate, and potential, among
others. The forward-looking statements contained in this report are based on our current
expectations, and those made at other times will be based on our expectations when the statements
are made. We cannot guarantee that any forward-looking statements will be realized.
The Private Securities Litigation Reform Act of 1995 provides a safe harbor for forward-looking
statements. In order to comply with the terms of the safe harbor, we note that a variety of
factors could cause actual results and experience to differ materially from anticipated results or
other expectations expressed in forward-looking statements. We also note that achievement of
anticipated results or expectations in forward-looking statements is subject to the possibility
that assumptions underlying forward-looking statements will prove to be inaccurate. Investors
should bear this in mind as they consider forward-looking statements.
The risks and uncertainties that may affect the operations, performance, development, and
results of our Applied Biosystems group and Celera group businesses include, but are not limited
to, those described in Managements
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Discussion and Analysis of Financial Condition and Results of Operation under the heading
Forward-Looking Statements and Risk Factors in Item 2 of Part I of this report. That description
amends and restates the risk factors associated with our Applied Biosystems group and Celera group
businesses that were previously disclosed in Item 1A of Part I of our 2006 Annual Report on Form
10-K and subsequently restated in our Quarterly Report on Form 10-Q for the first quarter of our
current fiscal year. Set forth below is a description of changes we have made to those risk
factors since they were disclosed in our 2006 10-K that may be material. The risks and
uncertainties that arise from our capital structure, particularly our two separate classes of
common stock, include, but are not limited to, those described in Item 1A of Part I of our 2006
Annual Report on Form 10-K under the heading Risk Factors-Risks Relating to a Capital Structure
with Two Separate Classes of Common Stock. There have not been any material changes to these risk
factors since they were disclosed in our 2006 10-K. We note that there may be additional risks and
uncertainties that could affect us or our businesses that are not currently known to us or that we
currently think are immaterial.
Changes to Applied Biosystems group risk factors
Following is the restated text of individual Applied Biosystems group risk factors that may have
changed materially from their previous disclosure in our 2006 10-K.
The Applied Biosystems group relies on other companies for the manufacture of some of its products
and also for the supply of some components of the products it manufactures on its own. Although
the Applied Biosystems group has contracts with most of these manufacturers and suppliers, their
operations could be disrupted. These disruptions could be caused by conditions unrelated to the
business or operations of the Applied Biosystems group, including the bankruptcy of the
manufacturer or supplier. Although the Applied Biosystems group has its own manufacturing
facilities, and generally believes it might be able to manufacture some of the products and
components currently sourced from other companies, it also believes that it could take considerable
time and resources to establish the capability to do so. Accordingly, if these other manufacturers
or suppliers are unable or fail to fulfill their obligations to the Applied Biosystems group, the
Applied Biosystems group might not be able to satisfy customer demand in a timely manner, and its
business could be harmed. For example, Delphi Medical Systems Texas Corporation, a supplier of
some instruments, parts, and components to the Applied Biosystems group under a manufacturing and
supply contract, filed a petition in the United States Bankruptcy Court on October 8, 2005, seeking
relief under the provisions of Chapter 11 of the federal Bankruptcy Code. Since the filing of the
bankruptcy petition, Delphi has continued to supply instruments, parts, and components to the
Applied Biosystems group under the contract, but Delphi informed the Applied Biosystems group that
it does not intend to continue performing under the contract after approximately May 2007. The
Applied Biosystems group intends to use its own existing manufacturing facilities to replace the
supply of some critical items that it has been purchasing from Delphi, and it is evaluating the use
of new suppliers for other critical items and is seeking to mitigate potential supply issues by
increasing inventory of some critical items. However, it is uncertain whether the Applied
Biosystems group will be able to transition the manufacture of these items to its own facilities,
hire new suppliers on acceptable terms, or increase inventories sufficiently to meet anticipated
demand, and it is also uncertain whether the Applied Biosystems group will be able to do so as
quickly as needed. Also, the Applied Biosystems group does not expect to replace the supply of all
items purchased from Delphi and accordingly some of its older, low demand products will be
discontinued earlier than originally planned.
The Applied Biosystems group is currently, and could in the future be, subject to lawsuits,
arbitrations, investigations, and other legal actions with private parties and governmental
entities, particularly involving claims for infringement of patents and other intellectual property
rights, and it may need to obtain licenses to intellectual property from others. The Applied
Biosystems group believes that it has meritorious defenses against the claims currently asserted
against it and intends to defend them vigorously. However, the outcome of legal actions is
inherently uncertain, and the Applied Biosystems group cannot be sure that it will prevail in any
of these actions. An adverse determination in some of the Applied Biosystems groups current legal
actions, particularly the cases described below, could harm our business and financial condition.
The Applied Biosystems groups products are based on complex, rapidly developing technologies.
These products could be developed without knowledge of previously filed patent applications that
mature into patents that cover some aspect of these technologies. In addition, because patent
litigation is complex and the outcome inherently uncertain, the Applied Biosystems groups belief
that its products do not infringe valid and enforceable patents owned by others could be
successfully challenged. The Applied Biosystems group has from time to time been notified that it
may be infringing patents and other intellectual property rights of others. Also, in the course of
its business, the Applied Biosystems group may from time to time have access to confidential or
proprietary information of others, and they could bring a claim against the Applied Biosystems
group asserting that the Applied
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Biosystems group had misappropriated their technologies, which
though not patented are protected as trade secrets, and had improperly incorporated those
technologies into the Applied Biosystems groups products. Due to these factors, there remains a
constant risk of intellectual property litigation and other legal actions, which could include
antitrust claims, affecting the Applied Biosystems group. The Applied Biosystems group has been
made a party to litigation and has been subject to other legal actions regarding intellectual
property matters, which have included claims of violations of antitrust laws. These actions
currently include the legal proceedings described in the following paragraph, some of which, if
determined adversely, could harm our business and financial condition. To avoid or settle legal
claims, it may be necessary or desirable in the future to obtain licenses relating to one or more
products or relating to current or future technologies, and the Applied Biosystems group may not be
able to obtain these licenses or other rights on commercially reasonable terms, or at all. In some
situations settlement of claims may require an agreement to cease allegedly infringing activities.
Several legal actions have been filed against us that could affect the intellectual property rights
of the Applied Biosystems group and its products and services, including the following:
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Enzo Biochem, Inc., Enzo Life Sciences, Inc., and Yale University have filed a
lawsuit against us alleging that we are infringing six patents due to the sale of sequencing
reagent kits, TaqMan® genotyping and gene expression assays, and the gene
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Molecular Diagnostics Laboratories has filed a class action complaint against us
and Hoffmann-La Roche, Inc. alleging anticompetitive conduct in connection with the sale of
Taq DNA polymerase. The anticompetitive conduct is alleged to arise from the prosecution
and enforcement of U.S. Patent No 4,889,818. This patent is assigned to Hoffmann-La Roche,
with whom we have a commercial relationship covering, among other things, this patent and
the sale of Taq DNA polymerase. |
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In response to patent infringement claims made by us against Stratagene
Corporation, Stratagene has filed counterclaims seeking declaratory judgment that our U.S.
Patent No. 6,814,934 in the field of real-time PCR is invalid and not infringed. |
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In response to a claim that we, MDS, Inc., and our Applied Biosystems/MDS Sciex
Instruments joint venture with MDS filed against Thermo Electron Corporation, Thermo
Electron has filed a counterclaim seeking a declaratory judgment that our U.S. Patent No.
4,963,736 is invalid. After the filing of this action against Thermo Electron, its
subsidiary Thermo Finnigan LLC filed a lawsuit against us alleging that we are infringing
one of its patents as a result of, for example, the Applied Biosystems groups
commercialization of the ABI PRISM® 3700 Genetic Analyzer. Thermo Finnigan
subsequently filed a second lawsuit against us, MDS, and the Applied Biosystems/MDS Sciex
Instruments joint venture alleging that we and the other defendants have infringed one of
Thermo Finnigans patents as a result of, for example, our commercialization of the API
5000 LC/MS/MS system. |
These cases are described in further detail in Part I, Item 3, of our 2006 Annual Report on Form
10-K under the heading Legal Proceedings Commercial Litigation, as updated by the information
in Part II, Item 1 of our subsequent Quarterly Reports on Form 10-Q, including Part II, Item 1 of
this report. The cost of litigation and the amount of management time associated with these cases
is expected to be significant. These matters might not be resolved favorably. If they are not
resolved favorably, we could be enjoined from selling the products or services in question or other
products or services as a result and monetary or other damages could be assessed against us. These
outcomes could harm the business or financial condition of our company, the Applied Biosystems
group, or the Celera group.
Following is the text of a risk factor, which we have added since the filing of our 2006 10-K,
relating to the Applied Biosystems group business.
Some of the intellectual property that is important to our business is owned by other companies or
institutions and licensed to us, and legal actions against them could harm the Applied Biosystems
groups business. Even if the Applied Biosystems group is not a party to these legal actions, an
adverse outcome could harm our business because it might prevent these other companies or
institutions from continuing to license intellectual property that we may need for our business.
Furthermore, an adverse outcome could result in infringement or other legal actions being brought
directly against us. For example, on November 8, 2006, a patent interference proceeding was
declared by the United States Patent and Trademark Office between Enzo Diagnostics, Inc. and the
California Institute of Technology, or Caltech, concerning a patent application owned by Enzo and
U.S. Patent No. 5,821,058, owned by Caltech. The 058 patent is exclusively licensed to us and
claims methods for DNA sequencing. The Patent Office has declared the interference in order to
resolve competing claims to inventorship of the subject matter of the interference. Although we
are not a party to this proceeding, as exclusive licensee we are involved in the
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prosecution of the interference, in cooperation with Caltech, and we are funding a substantial
portion of the cost of the prosecution. If Enzo prevails in the interference, the Patent Office
could revoke the claims of the 058 patent from Caltech and award substantially similar claims to
Enzo, which Enzo might then assert against our DNA sequencing products and possibly other products.
Changes to Celera group risk factors
Following is the restated text of an individual Celera group risk factor that may have changed
materially from its previous disclosure in our 2006 10-K.
The Celera group may infringe the intellectual property rights of others, may become involved in
expensive intellectual property legal proceedings, and may need to obtain licenses to intellectual
property from others. There has been substantial litigation and other legal proceedings regarding
patents and other intellectual property rights in the biotechnology, pharmaceutical, and
diagnostics industries. The intellectual property rights of biotechnology companies, including the
Celera group, are generally uncertain and involve complex factual, scientific, and legal questions.
The Celera groups success in diagnostic product development and therapeutic target discovery may
depend, in part, on its ability to operate without infringing the intellectual property rights of
others and to prevent others from infringing its intellectual property rights. Also, contractual
disputes related to existing license rights to patents owned by others may affect the Celera
groups ability to develop, manufacture, and sell its products.
The Celera group may initiate proceedings at the U.S. Patent and Trademark Office to determine its
patent rights with respect to others, referred to as interference proceedings. Also, the Celera
group may initiate patent litigation to enforce its patent rights or invalidate patents held by
others. These legal actions may similarly be initiated against the Celera group by others alleging
that the Celera group is infringing their rights. The cost to the Celera group of any patent
litigation or proceedings, even if the Celera group is successful, could be substantial, and these
legal actions may absorb significant management time.
If infringement claims against the Celera group are resolved unfavorably to the Celera group, the
Celera group may be enjoined from manufacturing or selling its products or services without a
license from a third party, and the Celera group may not be able to obtain a license on
commercially acceptable terms, or at all. Also, the Celera group could become subject to
significant liabilities to others if these claims are resolved unfavorably to the Celera group.
Similarly, our business could be harmed and we could be subject to liabilities because of lawsuits
brought by others against Abbott Laboratories, with whom we have a strategic alliance. For
example, Abbott has been sued by Innogenetics N.V. for patent infringement due to Abbotts sale of
hepatitis C virus genotyping analyte specific reagents, or ASRs, manufactured by the Celera group
for Abbott. In September 2006, a jury rendered a verdict against Abbott and awarded $7 million in
monetary damages to Innogenetics. We have agreed to share the cost of this litigation, including
these damages, and we are also subject to a permanent injunction that was issued by the court after
the jury verdict, in January 2007, that prohibits us or Abbott from manufacturing or selling
hepatitis C virus genotyping ASRs. Abbott has notified us that it intends to appeal the verdict in
this case, and it has filed an emergency motion with a Federal Court of Appeals seeking a stay of
the permanent injunction during the appeal process, but Abbott may not be successful. Abbott has
obtained a temporary stay of the permanent injunction pending the Courts consideration of the
emergency motion for a stay of the permanent injunction.
Following is the text of a risk factor, which we have added since the filing of our 2006 10-K,
relating to the Celera group business.
The U.S. Food and Drug Administration has issued a draft interpretation of the regulations
governing the sale of Analyte Specific Reagent products which could prevent or delay our or our
collaborators or licensees sales of these products and harm our business. In September 2006, the
U.S. Food and Drug Administration, or FDA, published Draft Guidance for Industry and FDA Staff:
Commercially Distributed Analyte Specific Reagents (ASRs): Frequently Asked Questions clarifying
the FDAs interpretation of the regulations governing the sale of Analyte Specific Reagent, or ASR,
products. ASRs are a class of products that do not require regulatory clearance or approval. The
draft guidance document contains an interpretation of the ASR regulations that is a departure from
what we believe to be the existing FDA practice and policy regarding products that can be
characterized as ASRs. If this draft guidance document becomes the final guidance document, and if
the FDA begins enforcing this interpretation of the ASR regulations, the Celera groups current ASR
products may not meet the regulatory definition of an ASR. If this were to occur, the Celera group
or its alliance partner Abbott Laboratories might have to stop selling these ASR products until the
products receive, if possible, the applicable FDA approval or clearance. Furthermore, the
enforcement of this new interpretation might prevent the Celera group or its collaborators or
licensees from developing any new products that would qualify as ASRs.
70
Item 2. Unregistered Sales of Equity Securities and Use of Proceeds.
This table provides information regarding our purchases of shares of Applera-Applied Biosystems
stock during the second quarter of fiscal 2007.
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Total Number of |
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Maximum Number |
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Shares |
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(or Approximate |
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Purchased as |
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Dollar Value) of |
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|
|
|
|
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Part of Publicly |
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|
Shares that May Yet |
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Total Number of |
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Average Price |
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Announced |
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Be Purchased Under |
|
|
|
Shares Purchased |
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Paid per |
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Plans or |
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the Plans or |
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Period |
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(1) |
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Share |
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Programs (2) |
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Programs (3) |
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October 1-October 31, 2006 |
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|
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|
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|
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|
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November 1-November 30, 2006 |
|
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376,212 |
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|
$ |
36.9584 |
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340,000 |
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December 1- December 31, 2006 |
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1,272,900 |
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$ |
37.1204 |
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1,272,900 |
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Total |
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1,649,112 |
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$ |
37.0835 |
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1,612,900 |
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(1) |
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Share repurchases reported in this column consist of shares repurchased under the
authorization described in footnote (3) below as well as 36,212 shares tendered by employees
in November 2006 to cover taxes relating to the vesting of restricted stock units. |
(2) |
|
Share repurchases reported in this column consist of shares repurchased under the
authorization described in footnote (3) below. Market purchases are reported in this column
based on trade settlement date. |
(3) |
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We previously announced that our Board of Directors has authorized the repurchase of shares
of Applera-Applied Biosystems stock from time to time to replenish shares issued under our
various employee stock benefit plans. This authorization has no set dollar or time limits and
delegates to our management discretion to purchase shares at times and prices it deems
appropriate through open market or negotiated purchases. Accordingly, the amounts in this
column do not reflect this authorization. |
This table provides information regarding our purchases of shares of Applera-Celera stock
during the second quarter of fiscal 2007.
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Total Number of |
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Maximum Number |
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Shares |
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(or Approximate |
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Purchased as |
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Dollar Value) of |
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Part of Publicly |
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Shares that May Yet |
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Total Number of |
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Average Price |
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Announced |
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Be Purchased Under |
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Shares Purchased |
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Paid per |
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Plans or |
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the Plans or |
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Period |
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(1) |
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Share |
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Programs |
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Program (2) |
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October 1-October 31, 2006 |
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November 1-November 30, 2006 |
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1,730 |
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$ |
14.9200 |
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December 1- December 31, 2006 |
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Total |
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1,730 |
|
|
$ |
14.9200 |
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(1) |
|
Share repurchases reported in this column consist of 1,730 shares tendered by employees in
November 2006 to cover taxes relating to the vesting of restricted stock units. |
(2) |
|
We previously announced that our Board of Directors has authorized the repurchase of shares
of Applera-Celera stock from time to time to replenish shares issued under our various
employee stock benefit plans. This authorization has no set dollar or time limits and
delegates to Company management discretion to purchase shares at times and prices it deems
appropriate through open market or negotiated purchases. Accordingly, the amounts in this
column do not reflect this authorization. No shares were purchased under this authorization
during the second quarter of our 2007 fiscal year. |
71
Item 4. Submission of Matters to a Vote of Security Holders.
We held our 2006 Annual Meeting of Stockholders on October 19, 2006. At that meeting, our
stockholders approved all proposals submitted to them for approval at the meeting as described in
our Proxy Statement and Notice of 2006 Annual Meeting of Stockholders dated September 6, 2006.
These proposals included the election of directors, the ratification of the selection of our
independent registered public accounting firm, amendments to our Restated Certificate of
Incorporation, and amendments to our stock incentive plans. The results of the voting of the
stockholders with respect to these matters is set forth below.
I. Election of Directors.
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Total Vote Withheld |
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Total Vote For |
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From |
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Each Director |
|
Each Director |
Richard H. Ayers |
|
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185,416,885 |
|
|
|
6,986,158 |
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Jean-Luc Bélingard |
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146,480,850 |
|
|
|
45,922,193 |
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Robert H. Hayes |
|
|
185,390,779 |
|
|
|
7,012,264 |
|
Arnold J. Levine |
|
|
189,682,893 |
|
|
|
2,720,150 |
|
William H. Longfield |
|
|
188,858,475 |
|
|
|
3,544,568 |
|
Theodore E. Martin |
|
|
190,581,933 |
|
|
|
1,821,110 |
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Carolyn W. Slayman |
|
|
184,490,106 |
|
|
|
7,912,937 |
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Orin R. Smith |
|
|
184,428,066 |
|
|
|
7,974,977 |
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James R. Tobin |
|
|
118,723,717 |
|
|
|
73,679,326 |
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Tony L. White |
|
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184,740,526 |
|
|
|
7,662,517 |
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II. Ratification of the selection of PricewaterhouseCoopers LLP as our independent
registered public accounting firm for the fiscal year ending June 30, 2007.
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FOR |
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AGAINST |
|
ABSTAIN |
|
|
|
|
|
184,083,046 |
|
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7,157,665 |
|
|
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1,162,332 |
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III. Approval of amendments to our Restated Certificate of Incorporation.
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|
|
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|
|
|
|
|
|
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FOR |
|
AGAINST |
|
ABSTAIN |
|
|
|
|
|
190,902,959 |
|
|
314,762 |
|
|
|
1,185,322 |
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IV. Approval of amendments to the Applera Corporation/Applied Biosystems Group
Amended and Restated 1999 Stock Incentive Plan.
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|
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FOR |
|
AGAINST |
|
ABSTAIN |
|
BROKER
NON-
VOTES |
|
135,570,399 |
|
|
28,333,021 |
|
|
|
2,179,866 |
|
|
|
26,319,757 |
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V. Approval of amendments to the Applera Corporation/Celera Genomics Group Amended
and Restated 1999 Stock Incentive Plan.
|
|
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|
|
|
|
|
|
|
|
|
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FOR |
|
AGAINST |
|
ABSTAIN |
|
BROKER
NON-
VOTES |
|
135,754,193 |
|
|
28,151,776 |
|
|
|
2,177,318 |
|
|
|
26,319,756 |
|
72
Item 6. Exhibits.
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3.1
|
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Restated Certificate of Incorporation of Applera Corporation
(incorporated by reference to Exhibit 3.1 to our Current Report on Form 8-K dated
November 30, 2006, and filed December 1, 2006 (Commission file number 001-04389)). |
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13.1
|
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Annual Report to Stockholders for the fiscal year ended June 30, 2006,
to the extent incorporated herein by reference (incorporated by reference to
Exhibit 13 to Annual Report on Form 10-K of the Company for the fiscal year ended
June 30, 2006 (Commission file number 001-04389)). |
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|
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31.1
|
|
Certification of Principal Executive Officer pursuant to Exchange Act
Rule 13a-14(a)/15d-14(a), as adopted pursuant to Section 302 of the Sarbanes-Oxley
Act of 2002. |
|
|
|
|
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31.2
|
|
Certification of Principal Financial Officer pursuant to Exchange Act
Rule 13a-14(a)/15d-14(a), as adopted pursuant to Section 302 of the Sarbanes-Oxley
Act of 2002. |
|
|
|
|
|
32.1
|
|
Certification of Chief Executive Officer pursuant to 18 U.S.C. Section
1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002. |
|
|
|
|
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32.2
|
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Certification of Chief Financial Officer pursuant to 18 U.S.C. Section
1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002. |
73
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has
duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.
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APPLERA CORPORATION
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By: |
/s/ Dennis L. Winger
|
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|
|
Dennis L. Winger |
|
|
|
Senior Vice President and
Chief Financial Officer |
|
|
|
|
|
|
By: |
/s/ Ugo D. DeBlasi
|
|
|
|
Ugo D. DeBlasi |
|
|
|
Vice President and
Controller
(Chief Accounting Officer) |
|
|
Dated:
February 7, 2007
74
EXHIBIT INDEX
Exhibit Number
|
|
|
31.1
|
|
Certification of Principal Executive Officer pursuant to Exchange Act Rule
13a-14(a)/15d-14(a), as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002. |
|
|
|
31.2
|
|
Certification of Principal Financial Officer pursuant to Exchange Act Rule
13a-14(a)/15d-14(a), as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002. |
|
|
|
32.1
|
|
Certification of Chief Executive Officer pursuant to 18 U.S.C. Section 1350, as adopted
pursuant to Section 906 of the Sarbanes-Oxley Act of 2002. |
|
|
|
32.2
|
|
Certification of Chief Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted
pursuant to Section 906 of the Sarbanes-Oxley Act of 2002. |