Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
JACOBSEN MICHAEL A
   2. Issuer Name and Ticker or Trading Symbol
OMEROS CORP [OMER] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
VP Finance and CAO
(Last)
(First)
(Middle)
201 ELLIOTT AVENUE WEST		 3. Date of Earliest Transaction (Month/Day/Year)
05/14/2018
(Street)

SEATTLE, WA 98119		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 05/14/2018   M   10,980 A $ 9.37 19,480 D  
Common Stock 05/14/2018   S(1)   10,980 D $ 22.45 8,500 D  
Common Stock 05/15/2018   M   12,812 A $ 9.37 21,312 D  
Common Stock 05/15/2018   S(1)   12,812 D $ 24.95 8,500 D  
Common Stock 05/15/2018   M   5,000 A $ 9.37 13,500 D  

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (Right to Buy) $ 9.37 05/14/2018   M     10,980   (2) 09/24/2023 Common Stock 10,980 $ 0 47,000 D  
Stock Option (Right to Buy) $ 9.37 05/15/2018   M     12,812   (2) 09/24/2023 Common Stock 12,812 $ 0 34,188 D  
Stock Option (Right to Buy) $ 9.37 05/15/2018   M     5,000   (2)(3) 09/24/2023 Common Stock 5,000 $ 0 29,188 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
JACOBSEN MICHAEL A
201 ELLIOTT AVENUE WEST
SEATTLE, WA 98119		       VP Finance and CAO  

Signatures

 /s/ Marcia S. Kelbon, attorney-in-fact on behalf of Michael A. Jacobsen   05/16/2018
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Open market sale pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on November 15, 2017, at which time the trading schedule, including sale periods, price and the number of shares to be sold, was established in accordance with Rule 10b5-1 under the Securities Exchange Act of 1934, as amended.
(2) 25% of the total number of shares subject to this option vested on September 3, 2014, and the remaining shares subject to the option vested and became exercisable in equal monthly installments over the 36 months following the initial vesting date.
(3) On May 15, 2018, the reporting person paid the exercise price and exercised options to purchase 5,000 shares of the company's common stock. These shares have not been sold and are held for the account of the reporting person. The options exercised in this transaction have the same vesting terms described in footnote 2.

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